Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 293515..293783 | Replicon | plasmid pDCE7-1 |
| Accession | NZ_CP090612 | ||
| Organism | Escherichia coli isolate DCE7 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 293553..293655 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 293515..293783 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LZG50_RS23230 (290672) | 290672..292111 | + | 1440 | WP_024242515.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| LZG50_RS23235 (292229) | 292229..292465 | + | 237 | WP_096890918.1 | DUF1480 family protein | - |
| LZG50_RS23240 (292570) | 292570..292761 | + | 192 | WP_001357784.1 | YebW family protein | - |
| LZG50_RS23245 (292762) | 292762..293418 | - | 657 | WP_000812743.1 | protein-serine/threonine phosphatase | - |
| - (293553) | 293553..293655 | - | 103 | NuclT_0 | - | Toxin |
| - (293515) | 293515..293783 | + | 269 | NuclAT_0 | - | Antitoxin |
| LZG50_RS23250 (293812) | 293812..294153 | - | 342 | WP_024248237.1 | YebY family protein | - |
| LZG50_RS23255 (294166) | 294166..295038 | - | 873 | WP_000879327.1 | copper homeostasis membrane protein CopD | - |
| LZG50_RS23260 (295042) | 295042..295416 | - | 375 | WP_000204700.1 | CopC domain-containing protein YobA | - |
| LZG50_RS23265 (295555) | 295555..295785 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| LZG50_RS23270 (295887) | 295887..296543 | + | 657 | WP_000011663.1 | carbon-nitrogen hydrolase family protein YobB | - |
| LZG50_RS23275 (296567) | 296567..297229 | + | 663 | WP_096841126.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | sodB / espL1 / flhA / flhB / cheZ / cheY / cheB / cheR / cheW / cheA / motB / motA / flhC / flhD / fliA / fliG / fliI / fliM / fliN / fliP / fliQ / fliR / rcsA / nleF / nleH2 / nleC / nleB2 | 1..420355 | 420355 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T231429 NZ_CP090612:c293655-293553 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT
Antitoxin
Download Length: 269 bp
>AT231429 NZ_CP090612:293515-293783 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT
