Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4834615..4835150 Replicon chromosome
Accession NZ_CP090597
Organism Pectobacterium aroidearum strain QJ002

Toxin (Protein)


Gene name relE Uniprot ID C6DJA0
Locus tag L0Y24_RS21645 Protein ID WP_015842269.1
Coordinates 4834863..4835150 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q6DB37
Locus tag L0Y24_RS21640 Protein ID WP_010281712.1
Coordinates 4834615..4834866 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y24_RS21615 (L0Y24_21595) 4829910..4831043 + 1134 WP_256599162.1 alkylhydroperoxidase domain protein -
L0Y24_RS21620 (L0Y24_21600) 4831086..4831709 - 624 WP_256599163.1 LysE family translocator -
L0Y24_RS21625 (L0Y24_21605) 4831891..4832595 + 705 WP_256599164.1 SMI1/KNR4 family protein -
L0Y24_RS21630 (L0Y24_21610) 4832665..4833420 + 756 WP_181845543.1 thiol:disulfide interchange protein DsbG -
L0Y24_RS21635 (L0Y24_21615) 4833455..4834360 - 906 WP_256599165.1 siderophore-interacting protein -
L0Y24_RS21640 (L0Y24_21620) 4834615..4834866 + 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
L0Y24_RS21645 (L0Y24_21625) 4834863..4835150 + 288 WP_015842269.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L0Y24_RS21650 (L0Y24_21630) 4835259..4836611 - 1353 WP_039474428.1 glutathione-disulfide reductase -
L0Y24_RS21655 (L0Y24_21635) 4836739..4837581 - 843 WP_015842271.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
L0Y24_RS21660 (L0Y24_21640) 4837800..4838528 + 729 WP_043881851.1 DUF1266 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11074.15 Da        Isoelectric Point: 10.3527

>T231397 WP_015842269.1 NZ_CP090597:4834863-4835150 [Pectobacterium aroidearum]
MSYSVKFREDALKEWLKLDKTIQQQFAKKLKKCCENPHIPSAKLRGMKDCYKIKLRASGFRLVYEVIDDVLIIAVVAVGK
RERSGVYHLASERMR

Download         Length: 288 bp

>T231397 NZ_CP126345:2714580-2714687 [Escherichia coli]
ATGACGCTCGCGAAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9117.47 Da        Isoelectric Point: 4.0637

>AT231397 WP_010281712.1 NZ_CP090597:4834615-4834866 [Pectobacterium aroidearum]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Download         Length: 252 bp

>AT231397 NZ_CP126345:c2714527-2714466 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3S0XQ75

Antitoxin

Source ID Structure
AlphaFold DB A0A0M2EZP0

References