Detailed information of TA system TA231393

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ccdAB/CcdA(antitoxin)
• Location: 1042775..1043114
• Replicon: chromosome
• Accession: NZ_CP090597
• Organism: Pectobacterium aroidearum strain QJ002

Toxin (Protein)

• Gene name: ccdB
• Uniprot ID: -
• Locus tag: L0Y24_RS04585
• Protein ID: WP_256599535.1
• Coordinates: 1042775..1042915 (-)
• Length: 47 a.a.

Antitoxin (Protein)

• Gene name: ccdA
• Uniprot ID: -
• Locus tag: L0Y24_RS04590
• Protein ID: WP_256599536.1
• Coordinates: 1042905..1043114 (-)
• Length: 70 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L0Y24_RS04565 (L0Y24_04565)	1038733..1039155	+	423	WP_039283843.1	MarR family transcriptional regulator	-
L0Y24_RS04570 (L0Y24_04570)	1039284..1040471	-	1188	WP_012773534.1	MFS transporter	-
L0Y24_RS04575 (L0Y24_04575)	1040587..1041543	+	957	WP_012773535.1	cupin domain-containing protein	-
L0Y24_RS04580 (L0Y24_04580)	1041815..1042552	-	738	WP_256599534.1	toll/interleukin-1 receptor domain-containing protein	-
L0Y24_RS04585 (L0Y24_04585)	1042775..1042915	-	141	WP_256599535.1	hypothetical protein	Toxin
L0Y24_RS04590 (L0Y24_04590)	1042905..1043114	-	210	WP_256599536.1	type II toxin-antitoxin system antitoxin CcdA	Antitoxin
L0Y24_RS04595 (L0Y24_04595)	1043129..1043377	-	249	WP_039312496.1	helix-turn-helix transcriptional regulator	-
L0Y24_RS04600 (L0Y24_04600)	1043384..1043527	+	144	Protein_894	helix-turn-helix domain-containing protein	-
L0Y24_RS04610	1044133..1044264	+	132	WP_256553759.1	hypothetical protein	-
L0Y24_RS04615 (L0Y24_04610)	1044496..1046649	+	2154	WP_256599537.1	ornithine decarboxylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Post-segregation antitoxin CcdA (2-68)

Sequences

Toxin

Protein

• Length: 47 a.a.
• Molecular weight: 4962.68 Da
• Isoelectric Point: 3.7896

>T231393 WP_256599535.1 NZ_CP090597:c1042915-1042775 [Pectobacterium aroidearum]
MTTELSSILIEVIGETIADLGEYADEIKDAINLIFGDLKGHSLLLS

Nucleotide

• Length: 141 bp

>T231393 NZ_CP126345:2062143-2062246 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin

Protein

• Length: 70 a.a.
• Molecular weight: 7656.59 Da
• Isoelectric Point: 4.9816

>AT231393 WP_256599536.1 NZ_CP090597:c1043114-1042905 [Pectobacterium aroidearum]
MKRRISIAVDKNDNQIPNATGIPISGLVNDVIGTEAYRIKTEAWKKENREGMGEVAQFIAQYGSFADDN

Nucleotide

• Length: 210 bp

>AT231393 NZ_CP126345:c2062284-2062013 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT