Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hicAB/- |
Location | 168691..169325 | Replicon | chromosome |
Accession | NZ_CP090597 | ||
Organism | Pectobacterium aroidearum strain QJ002 |
Toxin (Protein)
Gene name | hicA | Uniprot ID | - |
Locus tag | L0Y24_RS00710 | Protein ID | WP_181845733.1 |
Coordinates | 168691..168966 (+) | Length | 92 a.a. |
Antitoxin (Protein)
Gene name | hicB | Uniprot ID | - |
Locus tag | L0Y24_RS00715 | Protein ID | WP_181830203.1 |
Coordinates | 168963..169325 (+) | Length | 121 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
L0Y24_RS00695 (L0Y24_00695) | 165712..167082 | - | 1371 | WP_010281575.1 | envelope stress sensor histidine kinase CpxA | - |
L0Y24_RS00700 (L0Y24_00700) | 167079..167777 | - | 699 | WP_012772878.1 | envelope stress response regulator transcription factor CpxR | - |
L0Y24_RS00705 (L0Y24_00705) | 167931..168455 | + | 525 | WP_225181785.1 | cell-envelope stress modulator CpxP | - |
L0Y24_RS00710 (L0Y24_00710) | 168691..168966 | + | 276 | WP_181845733.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
L0Y24_RS00715 (L0Y24_00715) | 168963..169325 | + | 363 | WP_181830203.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
L0Y24_RS00720 (L0Y24_00720) | 169700..170887 | + | 1188 | WP_180779137.1 | sugar transporter | - |
L0Y24_RS00725 (L0Y24_00725) | 170931..171833 | + | 903 | WP_181845732.1 | CDF family cation-efflux transporter FieF | - |
L0Y24_RS00730 (L0Y24_00730) | 172041..173003 | + | 963 | WP_012772882.1 | 6-phosphofructokinase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 92 a.a. Molecular weight: 10051.64 Da Isoelectric Point: 11.1875
>T231388 WP_181845733.1 NZ_CP090597:168691-168966 [Pectobacterium aroidearum]
MQGKIASLRKKQRETLSQIFKTPVLSGVKWSNVESLITALGGEIKEGSGSRVRFLLNGSIARFHRPHPSPDTDKGALVNL
REWLESIGVKP
MQGKIASLRKKQRETLSQIFKTPVLSGVKWSNVESLITALGGEIKEGSGSRVRFLLNGSIARFHRPHPSPDTDKGALVNL
REWLESIGVKP
Download Length: 276 bp
>T231388 NZ_CP126345:1041573-1041908 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTATACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTATACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG
Antitoxin
Download Length: 121 a.a. Molecular weight: 13577.41 Da Isoelectric Point: 4.4981
>AT231388 WP_181830203.1 NZ_CP090597:168963-169325 [Pectobacterium aroidearum]
MTKALNTPNTMVVSGQPAIISYVPEIGMFRGKFIGLSGYCDFVADSINGLRNEGEISLREYLEDCQENGIEPYEREEKVK
TFTLRYPESFGERLTIAAAERQISVNTFIVETLNERMKQA
MTKALNTPNTMVVSGQPAIISYVPEIGMFRGKFIGLSGYCDFVADSINGLRNEGEISLREYLEDCQENGIEPYEREEKVK
TFTLRYPESFGERLTIAAAERQISVNTFIVETLNERMKQA
Download Length: 363 bp
>AT231388 NZ_CP126345:1041325-1041573 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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