Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 3183672..3184397 Replicon chromosome
Accession NZ_CP090596
Organism Pectobacterium aroidearum strain QJ003

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag L0Y20_RS14355 Protein ID WP_256598650.1
Coordinates 3183672..3183992 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag L0Y20_RS14360 Protein ID WP_256598651.1
Coordinates 3184062..3184397 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y20_RS14325 (L0Y20_14300) 3178970..3180385 + 1416 WP_181844696.1 diguanylate cyclase -
L0Y20_RS14330 (L0Y20_14305) 3180661..3180879 + 219 WP_015840821.1 KTSC domain-containing protein -
L0Y20_RS14335 (L0Y20_14310) 3181099..3181455 + 357 WP_256598647.1 hypothetical protein -
L0Y20_RS14340 (L0Y20_14315) 3181993..3182397 - 405 WP_256598648.1 tRNA(fMet)-specific endonuclease VapC -
L0Y20_RS14345 (L0Y20_14320) 3182397..3182627 - 231 WP_012765080.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
L0Y20_RS14350 (L0Y20_14325) 3182721..3183554 - 834 WP_256598649.1 DUF4942 domain-containing protein -
L0Y20_RS14355 (L0Y20_14330) 3183672..3183992 - 321 WP_256598650.1 TA system toxin CbtA family protein Toxin
L0Y20_RS14360 (L0Y20_14335) 3184062..3184397 - 336 WP_256598651.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
L0Y20_RS14365 (L0Y20_14340) 3184437..3184910 - 474 WP_256598652.1 DNA repair protein RadC -
L0Y20_RS14370 (L0Y20_14345) 3185033..3185383 - 351 WP_194430415.1 hypothetical protein -
L0Y20_RS14375 (L0Y20_14350) 3185441..3186274 - 834 WP_256598653.1 hypothetical protein -
L0Y20_RS14380 (L0Y20_14355) 3186421..3186579 - 159 WP_189654467.1 hypothetical protein -
L0Y20_RS14385 (L0Y20_14360) 3186763..3187650 - 888 WP_116238252.1 50S ribosome-binding GTPase -
L0Y20_RS14390 (L0Y20_14365) 3187746..3188777 - 1032 WP_011094394.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-106)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 11958.62 Da        Isoelectric Point: 4.5658

>T231385 WP_256598650.1 NZ_CP090596:c3183992-3183672 [Pectobacterium aroidearum]
MQATPAIPSGEDNPCPSPIAAWQQLLTYLMEKHYGLTLNDTPFCEENVIQEHIDAGITLVNAVNFLVEKYELVRIDRNGF
NWQEQSPFLTAVDVLRARRATGLLKT

Download         Length: 321 bp

>T231385 NZ_CP126345:c595227-594763 [Escherichia coli]
ATGGATTTTCCACAAAGGGTTAATGGTTGGGCGCTATATGCTCATCCCTGTTTTCAGGAAACCTACGACGCTTTAGTTGC
CGAAGTCGAGACATTAAAGGGAAAAGATCCTGAAAATTATCAGAGAAAAGCCGCCACAAAGTTATTGGCGGTAGTCCATA
AAGTGATTGAGGAGCATATCACGGTCAATCCATCATCACCGGCATTCCGTCATGGCAAGTCGTTAGGCTCTGGGAAAAAT
AAAGACTGGTCACGGGTAAAATTTGGTGCTGGTCGTTATCGTTTCTTCTTTCGTTATAGTGAAAAAGAGAAAGTCATCAT
TCTGGGATGGATGAACGATGAAAACACTCTGCGCACCTACGGTAAAAAAACAGATGCCTATACCGTATTCAGCAAAATGT
TAAAAAGAGGACATCCTCCTGCCGACTGGGAAAGCCTCACCCAAGAGACAGAAGAAAACCATTGA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12465.19 Da        Isoelectric Point: 6.2099

>AT231385 WP_256598651.1 NZ_CP090596:c3184397-3184062 [Pectobacterium aroidearum]
MSSVEAPEWGLKCAVTPRFGARLVQEGHRLHYLEDRASIVGTFSKTEARNLERCFPELIKQLEQKLRTGELNPCQQGCIV
LHCNEWTCEADTLGSFGYVYIAIYPSSAATQ

Download         Length: 336 bp

>AT231385 NZ_CP126345:c595562-595227 [Escherichia coli]
ATGCCCGCTAATGCTCGCTCTCACGCTGTACTGACCACTGAATCAAAGGTCACGATACGCGGACAAACAACTATCCCCGC
GCCAGTGCGTGAGGCCTTAAAACTGAAGCCAGGCCAGGACAGCATTCATTACGAAATTCTGCCTGGTGGGCAAGTCTTTA
TGTGCCGACTGGGAGATGAACAGGAGGATCATACTATGAATGCATTTTTGCGTTTTCTGGATGCAGATATCCAGAACAAC
CCGCAAAAAACTCGTCCATTCAACATTCAACAAGGAAAGAAACTTGTCGCTGGCATGGACGTCAACATTGATGATGAGAT
TGGCGACGACGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References