Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 1013517..1013856 Replicon chromosome
Accession NZ_CP090596
Organism Pectobacterium aroidearum strain QJ003

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag L0Y20_RS04560 Protein ID WP_256599535.1
Coordinates 1013517..1013657 (-) Length 47 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag L0Y20_RS04565 Protein ID WP_256599536.1
Coordinates 1013647..1013856 (-) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y20_RS04540 (L0Y20_04530) 1009475..1009897 + 423 WP_039283843.1 MarR family transcriptional regulator -
L0Y20_RS04545 (L0Y20_04535) 1010026..1011213 - 1188 WP_012773534.1 MFS transporter -
L0Y20_RS04550 (L0Y20_04540) 1011329..1012285 + 957 WP_012773535.1 cupin domain-containing protein -
L0Y20_RS04555 (L0Y20_04545) 1012557..1013294 - 738 WP_256599534.1 toll/interleukin-1 receptor domain-containing protein -
L0Y20_RS04560 (L0Y20_04550) 1013517..1013657 - 141 WP_256599535.1 hypothetical protein Toxin
L0Y20_RS04565 (L0Y20_04555) 1013647..1013856 - 210 WP_256599536.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
L0Y20_RS04570 (L0Y20_04560) 1013871..1014119 - 249 WP_039312496.1 helix-turn-helix transcriptional regulator -
L0Y20_RS04575 (L0Y20_04565) 1014126..1014269 + 144 Protein_889 helix-turn-helix domain-containing protein -
L0Y20_RS04585 1014875..1015006 + 132 WP_256553759.1 hypothetical protein -
L0Y20_RS04590 (L0Y20_04575) 1015238..1017391 + 2154 WP_256599537.1 ornithine decarboxylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 998115..1014119 16004


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Post-segregation antitoxin CcdA

(2-68)


Sequences

Toxin        


Download         Length: 47 a.a.        Molecular weight: 4962.68 Da        Isoelectric Point: 3.7896

>T231382 WP_256599535.1 NZ_CP090596:c1013657-1013517 [Pectobacterium aroidearum]
MTTELSSILIEVIGETIADLGEYADEIKDAINLIFGDLKGHSLLLS

Download         Length: 141 bp

>T231382 NZ_CP126344:c53726-53445 [Escherichia coli]
ATGACCTATGAACTGGCTTTTGACCGTAGAGCACTGAAGGAATGGCAGAAACTCGGCCACACCATCCGTGAACAATTCAA
AAAGAAACTGGCAGAACGGCTGGAAAATCCACGCGTACCCGCAGCCCGGTTACATGGTCATGCTGATCGCTATAAAATCA
AACTTCGTGCATCTGGCTACAGACTTGTATACCAAGTCATTGATGAGAAAGTCGTTTTACTCGTTATTGCCGTTGGAAGA
AGGGAAAGCAGCGAAGTCTATCAGATCGCAGATTTGCGCTAA

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7656.59 Da        Isoelectric Point: 4.9816

>AT231382 WP_256599536.1 NZ_CP090596:c1013856-1013647 [Pectobacterium aroidearum]
MKRRISIAVDKNDNQIPNATGIPISGLVNDVIGTEAYRIKTEAWKKENREGMGEVAQFIAQYGSFADDN

Download         Length: 210 bp

>AT231382 NZ_CP126344:c53967-53716 [Escherichia coli]
ATGAGCTATCAAATTCTGACAACTACAGCGGCCAGTATTACTGACCTGAAAAAAAATCCTATGGGAACCGTAGCTGAAGG
TGAAGGGGACGCTGTTGCGATCCTGAACCGAAACGAACCGGCGTTCTATTGCGTTCCACCAAAACTTTACGCCTACTATC
GGGAACTCGCTGAAGATGCTGAGTTAAACGCTGTTGCTGATGAGCGCATGAAAAACCCGGAAATTGTGAAGGTTAACCTG
GATGACCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References