Detailed information of TA system TA231379

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): stbDE/ParE-DnaT
• Location: 368695..369226
• Replicon: chromosome
• Accession: NZ_CP090596
• Organism: Pectobacterium aroidearum strain QJ003

Toxin (Protein)

• Gene name: stbE
• Uniprot ID: A0A1V2R9S3
• Locus tag: L0Y20_RS01630
• Protein ID: WP_012822123.1
• Coordinates: 368939..369226 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: stbD
• Uniprot ID: -
• Locus tag: L0Y20_RS01625
• Protein ID: WP_180778477.1
• Coordinates: 368695..368949 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L0Y20_RS01600 (L0Y20_01600)	363854..364444	-	591	WP_012773024.1	DnaA initiator-associating protein DiaA	-
L0Y20_RS01605 (L0Y20_01605)	364486..364881	-	396	WP_256599989.1	YraN family protein	-
L0Y20_RS01610 (L0Y20_01610)	364839..366857	-	2019	WP_256599289.1	penicillin-binding protein activator	-
L0Y20_RS01615 (L0Y20_01615)	366919..367806	+	888	WP_256599290.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
L0Y20_RS01625 (L0Y20_01625)	368695..368949	+	255	WP_180778477.1	plasmid stabilization protein	Antitoxin
L0Y20_RS01630 (L0Y20_01630)	368939..369226	+	288	WP_012822123.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
L0Y20_RS01635 (L0Y20_01635)	369405..370190	+	786	WP_256599291.1	4,5-DOPA dioxygenase extradiol	-
L0Y20_RS01640 (L0Y20_01640)	370260..371420	-	1161	WP_180778474.1	glutathionylspermidine synthase family protein	-
L0Y20_RS01645 (L0Y20_01645)	371432..372106	-	675	WP_012773030.1	DUF1190 family protein	-
L0Y20_RS01650 (L0Y20_01650)	372374..373765	-	1392	WP_182100458.1	outer membrane channel protein TolC	-
L0Y20_RS01655 (L0Y20_01655)	373900..374055	-	156	WP_012773032.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-82)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10997.94 Da
• Isoelectric Point: 10.7694

>T231379 WP_012822123.1 NZ_CP090596:368939-369226 [Pectobacterium aroidearum]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGVGK
REGSQVYSDTKGRSA

Nucleotide

• Length: 288 bp

>T231379 NZ_CP126343:c3718203-3717805 [Escherichia coli]
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAACTTGATGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGCGATGCACTCTACGACGACTCGTTTACCTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGTGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGAAGCGCATTTGGTATATTGTCAGGGTGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAACCTGA
ACCTCATAAACAGGCTCGAGATAACAACCAAATGCATAAAATTGGGAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9240.44 Da
• Isoelectric Point: 3.7947

>AT231379 WP_180778477.1 NZ_CP090596:368695-368949 [Pectobacterium aroidearum]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAMFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Nucleotide

• Length: 255 bp

>AT231379 NZ_CP126343:c3718499-3718206 [Escherichia coli]
ATGCATCGAATTCTCGCTGAAAAATCGGTCAATATTACTGAGTTACGTAAAAACCCAGCTAAATACTTTATTGATCAACC
GGTTGCGGTTCTTTCTAATAATCGCCCCGCAGGATATCTCTTAAGTGCCAGCGCATTCGAAGCGTTAATGGACATGCTTG
CTGAACAAGAGGAGAAAAAGCCCATAAAGGCGCGCTTCCGTCCAAGTGCTGCAAGATTAGAGGAAATTACACGCCGAGCT
GAAAAATATCTTAATGATATGACGGATGATGATTTCAATGACTTTAAGGAATAA

Structures

Toxin

• AlphaFold DB: A0A1V2R9S3