Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 3170771..3171496 Replicon chromosome
Accession NZ_CP090595
Organism Pectobacterium aroidearum strain QJ011

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag L0Y21_RS14240 Protein ID WP_256598650.1
Coordinates 3170771..3171091 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag L0Y21_RS14245 Protein ID WP_256598651.1
Coordinates 3171161..3171496 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y21_RS14210 (L0Y21_14190) 3166069..3167484 + 1416 WP_181844696.1 diguanylate cyclase -
L0Y21_RS14215 (L0Y21_14195) 3167760..3167978 + 219 WP_015840821.1 KTSC domain-containing protein -
L0Y21_RS14220 (L0Y21_14200) 3168198..3168554 + 357 WP_256598647.1 hypothetical protein -
L0Y21_RS14225 (L0Y21_14205) 3169092..3169496 - 405 WP_256598648.1 tRNA(fMet)-specific endonuclease VapC -
L0Y21_RS14230 (L0Y21_14210) 3169496..3169726 - 231 WP_012765080.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
L0Y21_RS14235 (L0Y21_14215) 3169820..3170653 - 834 WP_256598649.1 DUF4942 domain-containing protein -
L0Y21_RS14240 (L0Y21_14220) 3170771..3171091 - 321 WP_256598650.1 TA system toxin CbtA family protein Toxin
L0Y21_RS14245 (L0Y21_14225) 3171161..3171496 - 336 WP_256598651.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
L0Y21_RS14250 (L0Y21_14230) 3171536..3172009 - 474 WP_256598652.1 DNA repair protein RadC -
L0Y21_RS14255 (L0Y21_14235) 3172132..3172482 - 351 WP_194430415.1 hypothetical protein -
L0Y21_RS14260 (L0Y21_14240) 3172540..3173373 - 834 WP_256598653.1 hypothetical protein -
L0Y21_RS14265 (L0Y21_14245) 3173520..3173678 - 159 WP_189654467.1 hypothetical protein -
L0Y21_RS14270 (L0Y21_14250) 3173862..3174749 - 888 WP_116238252.1 50S ribosome-binding GTPase -
L0Y21_RS14275 (L0Y21_14255) 3174845..3175876 - 1032 WP_011094394.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-106)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 11958.62 Da        Isoelectric Point: 4.5658

>T231374 WP_256598650.1 NZ_CP090595:c3171091-3170771 [Pectobacterium aroidearum]
MQATPAIPSGEDNPCPSPIAAWQQLLTYLMEKHYGLTLNDTPFCEENVIQEHIDAGITLVNAVNFLVEKYELVRIDRNGF
NWQEQSPFLTAVDVLRARRATGLLKT

Download         Length: 321 bp

>T231374 NZ_CP126343:2653518-2653625 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12465.19 Da        Isoelectric Point: 6.2099

>AT231374 WP_256598651.1 NZ_CP090595:c3171496-3171161 [Pectobacterium aroidearum]
MSSVEAPEWGLKCAVTPRFGARLVQEGHRLHYLEDRASIVGTFSKTEARNLERCFPELIKQLEQKLRTGELNPCQQGCIV
LHCNEWTCEADTLGSFGYVYIAIYPSSAATQ

Download         Length: 336 bp

>AT231374 NZ_CP126343:c2653471-2653405 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References