Detailed information of TA system TA231364

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): stbDE/ParE-DnaT
• Location: 4435476..4436007
• Replicon: chromosome
• Accession: NZ_CP090594
• Organism: Pectobacterium aroidearum strain QJ034

Toxin (Protein)

• Gene name: stbE
• Uniprot ID: -
• Locus tag: L0Y22_RS19850
• Protein ID: WP_256542520.1
• Coordinates: 4435476..4435763 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: stbD
• Uniprot ID: -
• Locus tag: L0Y22_RS19855
• Protein ID: WP_180778477.1
• Coordinates: 4435753..4436007 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L0Y22_RS19830 (L0Y22_19805)	4430790..4432181	+	1392	WP_181829970.1	outer membrane channel protein TolC	-
L0Y22_RS19835 (L0Y22_19810)	4432596..4433270	+	675	WP_012773030.1	DUF1190 family protein	-
L0Y22_RS19840 (L0Y22_19815)	4433282..4434442	+	1161	WP_180778474.1	glutathionylspermidine synthase family protein	-
L0Y22_RS19845 (L0Y22_19820)	4434512..4435297	-	786	WP_039524247.1	4,5-DOPA dioxygenase extradiol	-
L0Y22_RS19850 (L0Y22_19825)	4435476..4435763	-	288	WP_256542520.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
L0Y22_RS19855 (L0Y22_19830)	4435753..4436007	-	255	WP_180778477.1	plasmid stabilization protein	Antitoxin
L0Y22_RS19865 (L0Y22_19840)	4436895..4437782	-	888	WP_182100461.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
L0Y22_RS19870 (L0Y22_19845)	4437844..4439862	+	2019	WP_256542521.1	penicillin-binding protein activator	-
L0Y22_RS19875 (L0Y22_19850)	4439820..4440215	+	396	WP_180778506.1	YraN family protein	-
L0Y22_RS19880 (L0Y22_19855)	4440279..4440869	+	591	WP_012773024.1	DnaA initiator-associating protein DiaA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-78)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10967.91 Da
• Isoelectric Point: 10.7694

>T231364 WP_256542520.1 NZ_CP090594:c4435763-4435476 [Pectobacterium aroidearum]
MIYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGGGK
REGSQVYSDTKGRSA

Nucleotide

• Length: 288 bp

>T231364 NZ_CP126343:666374-666688 [Escherichia coli]
ATGCACCTGATAACTCAAAAAGCATTGAAAGATGCTGCGGAAAAATACCCGCAACATAAAACGGAGTTGGTGGCTCTGGG
GAACACGATTGCTAAGGGATATTTCAAAAAACCTGAGTCATTAAAAGCAGTATTCCCATCTCTGGATAACTTCAAATATC
TGGATAAGCATTATGTTTTCAATGTTGGGGGCAATGAATTACGTGTTGTAGCAATGGTCTTTTTTGAATCGCAAAAGTGC
TACATACGTGAAGTTATGACGCATAAAGAATACGATTTCTTTACCGCTGTTCATCGTACTAAGGGGAAAAAATGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9240.44 Da
• Isoelectric Point: 3.7947

>AT231364 WP_180778477.1 NZ_CP090594:c4436007-4435753 [Pectobacterium aroidearum]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAMFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Nucleotide

• Length: 255 bp

>AT231364 NZ_CP126343:666685-667101 [Escherichia coli]
ATGATTGCGATTGCCGACATCTTGCAAGCAGGAGAAAAGCTAACTGCTGTGGCACCTTTTCTGGCGGGTATTCAGAACGA
GGAACAATACACCCAGGCGCTGGAACTGGTAGATCATCTGCTGCTCAACGATCCTGAAAACCCCTTGCTGGATCTGGTGT
GTGCCAAAATAACCGCGTGGGAAGAATCAGCGCCCGAATTTGCGGAATTTAATGCCATGGCTCAAGCCATGCCTGGCGGT
ATAGCCGTGATTCGTACCCTTATGGATCAATATGGTTTAACCCTTTCCGATCTGCCGGAAATTGGCAGTAAATCTATGGT
GTCACGCGTTTTGAGCGGGAAGAGGAAATTAACGCTGGAACACGCTAAAAAATTGGCAACGCGATTCGGCATTTCTCCCG
CCTTGTTTATTGATTAA