Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 4216538..4218236 Replicon chromosome
Accession NZ_CP090594
Organism Pectobacterium aroidearum strain QJ034

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag L0Y22_RS18910 Protein ID WP_256542451.1
Coordinates 4217307..4218236 (+) Length 310 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag L0Y22_RS18905 Protein ID WP_256542450.1
Coordinates 4216538..4217320 (+) Length 261 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y22_RS18865 (L0Y22_18840) 4211548..4211808 + 261 WP_256542445.1 helix-turn-helix transcriptional regulator -
L0Y22_RS18870 (L0Y22_18845) 4212274..4214124 + 1851 WP_256542446.1 endonuclease NucS -
L0Y22_RS18875 (L0Y22_18850) 4214366..4214563 + 198 WP_256542447.1 hypothetical protein -
L0Y22_RS18880 (L0Y22_18855) 4214692..4214934 - 243 WP_256542448.1 helix-turn-helix transcriptional regulator -
L0Y22_RS18885 (L0Y22_18860) 4215038..4215292 + 255 WP_225181522.1 helix-turn-helix transcriptional regulator -
L0Y22_RS18890 (L0Y22_18865) 4215378..4215626 + 249 WP_225181523.1 helix-turn-helix transcriptional regulator -
L0Y22_RS18895 (L0Y22_18870) 4215641..4215843 + 203 Protein_3693 type II toxin-antitoxin system antitoxin CcdA -
L0Y22_RS18900 (L0Y22_18875) 4216003..4216320 + 318 WP_256542449.1 hypothetical protein -
L0Y22_RS18905 (L0Y22_18880) 4216538..4217320 + 783 WP_256542450.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
L0Y22_RS18910 (L0Y22_18885) 4217307..4218236 + 930 WP_256542451.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
L0Y22_RS18915 (L0Y22_18890) 4218620..4219522 - 903 WP_181847077.1 LysR family transcriptional regulator -
L0Y22_RS18920 (L0Y22_18895) 4219651..4219914 + 264 WP_012773200.1 DUF2798 domain-containing protein -
L0Y22_RS18925 (L0Y22_18900) 4220080..4220463 - 384 Protein_3699 MBL fold metallo-hydrolase -
L0Y22_RS18930 (L0Y22_18905) 4220436..4221146 - 711 WP_256543452.1 thiamine pyrophosphate-binding protein -
L0Y22_RS18935 (L0Y22_18910) 4221425..4222357 - 933 WP_256542452.1 phosphoenolpyruvate mutase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(14-261)

Antitoxin

Transcriptional regulator, AbiEi 3 antitoxin, Type IV TA system

(95-247)


Sequences

Toxin        


Download         Length: 310 a.a.        Molecular weight: 35068.40 Da        Isoelectric Point: 5.9092

>T231362 WP_256542451.1 NZ_CP090594:4217307-4218236 [Pectobacterium aroidearum]
MDHRDIYARQVKLLMTALPYVAKEPCFALKGGTAINLFVQDFPRLSVDIDLVYQTFIDRDTDLIAIDDALMRITESLNGR
QGLTAIQQENKADEKRIIVNTADAQIKIEVSPVWRGLLLPPAEMPVCEQVEMEYGFTTMSVVSLADLYGGKICAALDRQH
PRDLFDVLNMLEKPCLTREIFDGFLCYLAGHPRPIAELLAPNWDTSRIATLYAQEFSGMTQQETSLESLLSVATLLPQAL
KSHFTAQDRQFLLSYKQNNPDWSLYRYPDIQHLPAIRWKQRNLSALHAKNPAKFSAAVGKLEKVLEQHF

Download         Length: 930 bp

>T231362 NZ_CP126342:c4594129-4593380 [Pseudomonas otitidis]
ATGGACATCTGGAGCGCATGCGACGGCGAACGCCACATCGCCCCCCTGCGCGGGCGCGTGGTGCGCCTGGTGGAGAGCCA
GGAACAGGTGGCGACCCTGCAACTGGTGGACAACCTCGCCGAACAGGCCCTGCTGGAAGAACTCATCGAGACCAGCAAAC
CGCCCCTGCCGCGCAGCGCCGAGCCGCTGCATTACCTGCTCAAGACCCCGTTCCGCTACCCGCCGCTGCGCTGGGGCTCG
CGCTTCGGCACGGTGCACGAGCCCAGCCTGTTCTACGCCGCTGCGCGCCTGGAGACGGCCATGGCCGAAGGCGCCTTCTA
CCGCTTCGTGCTGTGGAGCGGCATGGCCACCCCACCGCCCAGCGGACGCATCCTCTCGGAGCACGCCTCCTTCGAGGCGC
GCTTCCAGGTGGAGCGCGGCGTGAGCCTGCAGAACCCGCCGTTCGATGCCTACCCGGCGTTGCTCGATCGCCGCGACTAC
CGCGCCACCCAGGCCCTGGGGGCGGCCATGCGTGCCGCCGGGGTCGAAGCCTTCGAATACCGCTCCGCCCGCTGCCCGCA
GCAGGGGCTGAACATCGCCCTGTTCACCCCCGACGCCTTCACCGAACGGCGCCCGCGCAACCTCACCCCCTGGTTCTGCG
AAACCACGGCCGACTACGTCGCCTACAAGCACGCCCAGGCGCCGGACCAGCCCCGTCTGTTCCGCCGCGAAGCCTTCCTG
GTGGACGGCGTCATCCCCCAGCCGGCGTGA

Antitoxin


Download         Length: 261 a.a.        Molecular weight: 29347.66 Da        Isoelectric Point: 9.0688

>AT231362 WP_256542450.1 NZ_CP090594:4216538-4217320 [Pectobacterium aroidearum]
MTNYLNWLMQNTLPGQVLLQSWLTRNGIDRKLSYVYVQNGWLRRIAHGVYCRTGREPDWVDAVYCLQTQWEKPVRVAGLT
SLALQGYSHYTELGKPQIWLTLPAYIKLPGWFTAFKPSATFVVLYTSGLSVDVMPLTTELRIGDRRLTGSMPELAAYEIA
SGVPAQISFEHADALFQGLNLLSPRKLQALLYASHSVKTNRVMLYLAQRNGHPYFQYLDKSGIETGAGKRQIVPGGWLEP
DYQITVPREFKSEGVEDGSS

Download         Length: 783 bp

>AT231362 NZ_CP126342:c4594519-4594148 [Pseudomonas otitidis]
ATGAGCGCGCTGACCCGCCCCCACCTCGATCCCGACGCCGTCCTGGCCAAGGCCCTGCTCAACACCCGCGAGCAACTGGG
GCTGACCCGCCAGCAACTTGCCGACATCGTCGGCGTCCACCGCACCGTCGTCACCCGCTGGGCCGACGCCGGTAGCATCC
GCCCGCAGAGCAAGACCGGTGAACTGGCGCTGCTGGTGATCCGCATCTACCGCGCCCTGTTCGCGCTGTTCGGCGGCAAC
CTCGAGGACATGCGCCACTTCCTGCGCACCGAGAACCGTCACCTCGGCGGCGTGCCCCTGGAGCTGATGGGGCAGGTGCA
GGGGCTGGTGCGGGTGGTGGAGTACCTCGACGCCATTCGCGGCAAGGTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References