Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3972160..3972820 Replicon chromosome
Accession NZ_CP090594
Organism Pectobacterium aroidearum strain QJ034

Toxin (Protein)


Gene name cptA Uniprot ID A0A7W2E4X8
Locus tag L0Y22_RS17705 Protein ID WP_012773341.1
Coordinates 3972160..3972573 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID C6D8Y5
Locus tag L0Y22_RS17710 Protein ID WP_012773340.1
Coordinates 3972554..3972820 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y22_RS17680 (L0Y22_17655) 3967537..3968436 - 900 WP_012773347.1 site-specific tyrosine recombinase XerD -
L0Y22_RS17685 (L0Y22_17660) 3968748..3970076 + 1329 WP_181845156.1 MFS transporter -
L0Y22_RS17690 (L0Y22_17665) 3970239..3970757 + 519 WP_012773344.1 flavodoxin FldB -
L0Y22_RS17695 (L0Y22_17670) 3970786..3971109 + 324 WP_180777498.1 hypothetical protein -
L0Y22_RS17700 (L0Y22_17675) 3971155..3972090 - 936 WP_256542328.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
L0Y22_RS17705 (L0Y22_17680) 3972160..3972573 - 414 WP_012773341.1 protein YgfX Toxin
L0Y22_RS17710 (L0Y22_17685) 3972554..3972820 - 267 WP_012773340.1 FAD assembly factor SdhE Antitoxin
L0Y22_RS17715 (L0Y22_17690) 3973056..3974057 + 1002 WP_256542329.1 tRNA-modifying protein YgfZ -
L0Y22_RS17720 (L0Y22_17695) 3974237..3974884 - 648 WP_012773338.1 hemolysin III family protein -
L0Y22_RS17725 (L0Y22_17700) 3975297..3975905 + 609 WP_181829659.1 HD domain-containing protein -
L0Y22_RS17730 (L0Y22_17705) 3975949..3976953 + 1005 WP_256542330.1 LacI family DNA-binding transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16302.21 Da        Isoelectric Point: 10.6525

>T231361 WP_012773341.1 NZ_CP090594:c3972573-3972160 [Pectobacterium aroidearum]
VAQWQCDLRVSWRMQLLSLIVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLQAVNGKDRQQLWLASDSMGDDEWRHLRQLLLQQKNWAR

Download         Length: 414 bp

>T231361 NZ_CP126342:c2467645-2467460 [Pseudomonas otitidis]
ATGAAGTACAGCGAGTTCCGGCGATGGCTGGAGTCCCAAGGGGTCACGTTCTCGAAGTCAGCCAAAGGCAGCCACTTCAA
GATCAGATACCGGGGCCGACAGACGATCTTCCCGAATCACGGCGCTAAGGAAATCAGCGAAGGACTCAGGAAGGACATCA
TCAAACAGCTAGGCCTCAAGGACTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10465.94 Da        Isoelectric Point: 6.2223

>AT231361 WP_012773340.1 NZ_CP090594:c3972820-3972554 [Pectobacterium aroidearum]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLSDSDKRTFVRLLQSDDPDLFNWLMNHGEPKDGELKRMISLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT231361 NZ_CP126342:c2467403-2466981 [Pseudomonas otitidis]
ATGGTCAACTACCCCATCTCGGTCCACCGAGAAAACGACCACTACTGGTCGTCGTGCCCGGACTTGCCGGAGGCGCATAG
CGCCGGCGATACCCTGGAAGAACTGCTGGCGAATGCTGTGGAAGGCATTCAGCTGGCCATGTCCATTTACGTCGACCAGG
GCCGGGAGATTCCGGCCGCAAGCGAACCGGAGCCGGGTCAGCATGTGATCTATCAGCCCATTCAGTTCGCTGCGAAGGCT
GCCCTGTGGAACGCCATGCGCGAGCAAGGCCTGCGCGTAGCCGACCTGGCCCGGTTGCTGGAGGTTTCGCACCCAGTAGC
TGCCCGACTGGTGGACTTTGAGCACACGTCGAAGATTGAACAGCTTGAGCGCGCCCTTGCCTCTCTGGGCAAGCGCATCA
CCCTGAGCCTGGAGGCTGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7W2E4X8

Antitoxin

Source ID Structure
AlphaFold DB A0A7W2E501

References