Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3777728..3778506 Replicon chromosome
Accession NZ_CP090594
Organism Pectobacterium aroidearum strain QJ034

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag L0Y22_RS16880 Protein ID WP_256542279.1
Coordinates 3777728..3778216 (-) Length 163 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag L0Y22_RS16885 Protein ID WP_205947014.1
Coordinates 3778213..3778506 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y22_RS16845 (L0Y22_16820) 3772988..3773200 - 213 WP_256542275.1 hypothetical protein -
L0Y22_RS16850 (L0Y22_16825) 3773526..3773768 - 243 WP_205947008.1 helix-turn-helix transcriptional regulator -
L0Y22_RS16855 (L0Y22_16830) 3773872..3774126 + 255 WP_039285388.1 helix-turn-helix transcriptional regulator -
L0Y22_RS16860 (L0Y22_16835) 3774212..3774460 + 249 WP_256542276.1 helix-turn-helix transcriptional regulator -
L0Y22_RS16865 (L0Y22_16840) 3774475..3774693 + 219 WP_256542277.1 type II toxin-antitoxin system antitoxin CcdA -
L0Y22_RS16870 (L0Y22_16845) 3774741..3775000 + 260 Protein_3297 type II toxin-antitoxin system toxin CcdB -
L0Y22_RS16875 (L0Y22_16850) 3775381..3777570 - 2190 WP_256542278.1 AAA family ATPase -
L0Y22_RS16880 (L0Y22_16855) 3777728..3778216 - 489 WP_256542279.1 GNAT family N-acetyltransferase Toxin
L0Y22_RS16885 (L0Y22_16860) 3778213..3778506 - 294 WP_205947014.1 DUF1778 domain-containing protein Antitoxin
L0Y22_RS16890 (L0Y22_16865) 3778715..3779671 - 957 WP_256542280.1 AraC family transcriptional regulator -
L0Y22_RS16895 (L0Y22_16870) 3779787..3780974 + 1188 WP_256542281.1 MFS transporter -
L0Y22_RS16900 (L0Y22_16875) 3781101..3781523 - 423 WP_012773533.1 MarR family transcriptional regulator -
L0Y22_RS16905 (L0Y22_16880) 3781684..3782703 + 1020 WP_256542282.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(76-143)

Antitoxin

Vibrio phage ICP1, Orf50

(14-88)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 17421.24 Da        Isoelectric Point: 7.8046

>T231360 WP_256542279.1 NZ_CP090594:c3778216-3777728 [Pectobacterium aroidearum]
MISAPEPLHAEHVLSSFCCGVESMDNWLKQRAMKNQVTGASRTFVSCDGSKVLAYYSLASSAVATNAAPGRFRRNMPDPI
PVVVLGRLAVDKSLHGQGVGRALVRDVGLRVIQVADTIGIRGMLVHALSDEAREFYLRVGFEPSPIDPMLLMVTLGDLVG
SV

Download         Length: 489 bp

>T231360 NZ_CP126342:1730356-1730925 [Pseudomonas otitidis]
ATGTTCAATCCGCAACCGGTCACCCTGCAGCGTGGCGCATTGCGCCTGGAGCCACTGGGGGAGGCCGATGTCAGCGAGCT
GGCGGCCCTGGCCGAAGCCAATCGCAACGAACTGGTCTACATGAGCGGCCCGCTGCGGCCGGACTGGTACCGCCAGGGCA
TCGCCCAGCAGCGCGAAGGCCAGGCCGTGGTGTTCGCCATCCGCCTGGGTGACCGCCTGGTGGGCACCAGCCGATTCGCC
GAATTCATGCCGGCCCTGCCCGCCGTGGAGATCGGCTGGACCTGGCTGGCCGGCAGCGAGCACGGCACCGGCCTCAACGC
CTCGATCAAGTACCTGATGCTGCGCCACGCCTTCGAGGAGTGGCAGGTGGTGCGGGTGCAGCTGAAGACCGCCGGCAGCA
ACCTGCGCTCGCAACGGGCCATCGAGAAGCTCGGCGCGGTGCGTGAGGGGGTGCTGCGCAACCACCGCCGCCTGGCCGAC
GGGCGCCTGGACGACAGCGTCATGTTCAGCATCACCGACCACGAGTGGCCGGCGGTGAAGCAGGCCCTGGAAGCCGCATT
CGTCCAATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10892.43 Da        Isoelectric Point: 10.1968

>AT231360 WP_205947014.1 NZ_CP090594:c3778506-3778213 [Pectobacterium aroidearum]
MPATNSVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIDQRIIMADPDAYQEFLTRLDQAPSPN
AALRKTMQTSAPWEQKK

Download         Length: 294 bp

>AT231360 NZ_CP126342:1730922-1731764 [Pseudomonas otitidis]
ATGAGCACGGGCGGTGAGCGCACGCGCTTCTGGCAGGCCAGTGCGCTGAGCGGGGTCGAGCTCCTGCATGCGCGCTACAT
CCAGCATCGCTTCTCGCCCCACGTGCACGAAGGCTACGTCTTCACCATCCTCGAGTCCGGCGCCCAGCGCTTCCGCCACC
GCGGCAGCGACCACCTGGCCGCCGTCGGCAGCATGGTGCTGATCAACCCGGACGAGCTGCACACCGGCTCCAAGGCCCAC
GAGGAAGGCTGGCGCTACCGGGGGTTCTACCCCGACCTGCACCGGGTGACCGATGTGCTGGACGAGCTGGAGATCGCCAC
CGGCGGCCTGCCCACCTTCGCCGACAGCGTGCTGCATGACCCCGAGGTGACCCGCCGCTTCCTCGACCTGCACTGCCTGC
TGGAGCGCAATGCCTCCGCCCTGGAGCAGCAGGTGGCCTGGCGCGAGGCGATCCTGCTGCTGTTCAGCCGCCACGCGCGC
ATCGGTGCGCCACGGCCGGCGGGGCAGGAGCCCCAGGCCGTGGCGCTGGCCCGCGAGGTGCTGGCGGCGCGCCTGGCCTC
GCCGCCATCCCTGGAGGAACTGGCGGCCCTGGTGGGGCTTTCGCCGTTCCACTTCGCCCGGGTCTTCCAGCGCGCCACCG
GGATGCCGCCCCACGCGTGGCTCAAGCAGCGTCGCCTGGAGCAGGCGCGGGCCATGCTGCGCAGCGGTTGCGCGCCGTTG
TCGGTGGCGATGCAGCTGGGCTTTGCCGACCAGAGCCACCTGACCCGTCAGTTCAAGCAGACCTATGGTGTAGGTCCCGG
CGAATACCGGACCGCCAGCGCAAGATCGTTCAAGACCGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References