Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 2899433..2900003 Replicon chromosome
Accession NZ_CP090594
Organism Pectobacterium aroidearum strain QJ034

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag L0Y22_RS12945 Protein ID WP_137740513.1
Coordinates 2899433..2899717 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag L0Y22_RS12950 Protein ID WP_256543426.1
Coordinates 2899764..2900003 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y22_RS12935 (L0Y22_12925) 2897531..2898931 - 1401 WP_256541972.1 HEPN domain-containing protein -
L0Y22_RS12940 (L0Y22_12930) 2899198..2899443 + 246 WP_014914993.1 CopG family ribbon-helix-helix protein -
L0Y22_RS12945 (L0Y22_12935) 2899433..2899717 + 285 WP_137740513.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L0Y22_RS12950 (L0Y22_12940) 2899764..2900003 + 240 WP_256543426.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
L0Y22_RS12955 (L0Y22_12945) 2900061..2900414 + 354 WP_256541973.1 hypothetical protein -
L0Y22_RS12960 2900675..2900800 + 126 WP_256541974.1 hypothetical protein -
L0Y22_RS12965 (L0Y22_12950) 2901418..2902296 + 879 WP_015839856.1 hypothetical protein -
L0Y22_RS12970 (L0Y22_12955) 2902457..2902921 - 465 WP_256541975.1 GyrI-like domain-containing protein -
L0Y22_RS12975 (L0Y22_12960) 2903156..2903485 - 330 WP_181847683.1 DHCW motif cupin fold protein -
L0Y22_RS12980 (L0Y22_12965) 2903551..2904087 - 537 WP_182099558.1 rhodanese family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-79)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11098.90 Da        Isoelectric Point: 9.7867

>T231357 WP_137740513.1 NZ_CP090594:2899433-2899717 [Pectobacterium aroidearum]
MEIKWLRKAAANLEAEYLYIAQDDPQAASQFVDEVQRLTELLPQQPAMGRPGRVPGTRELVLTHYPYIIPYRVKDNMLQI
LRIFHTHRRLPSKW

Download         Length: 285 bp

>T231357 NZ_CP126341:c4114360-4113947 [Enterobacter cloacae]
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCGTGGCGCTCGCAGTGGATGTCGTTATTGCTCCACGGCCTGGTCGCGGC
ATTTGTTTTACTGATGCCGTGGCCGCTTAGCTATACGCCGCTGTGGCTGTTGTTGCTGTCGTTCGTCGTTTTTGACAGCG
TGCGCAGCCAGCGCCGGATCAATGCCCGCCAGGGTGAGATCAAATTACTGATGGACTCCCGCCTGCGCTGGCAGGATAAA
GAGTGGGATATCCTCGGTATGCCCTGGATGCTCAGTTCCGGTATGATGCTACGGTTACGCCAGGTGGGCGGCGGTAAGTG
CCAGCATCTGTGGCTGGCCGCCGACAGTATGGATATTGCGGAGTGGCGGGAACTGCGCCGGATGCTACTGCAGCAGCAAC
CGACGCAGGAATAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9185.64 Da        Isoelectric Point: 8.5173

>AT231357 WP_256543426.1 NZ_CP090594:2899764-2900003 [Pectobacterium aroidearum]
MGNVTFRIGDDLKKRSYAALKKLGITPSEAFRLTLEYIAENERLPFKQKLLNDEDVELVEVVRERLRNPKPVRVTLDDL

Download         Length: 240 bp

>AT231357 NZ_CP126341:c4114607-4114341 [Enterobacter cloacae]
ATGGATATTAACAACAAGGCCCGTATTCACTGGGCATGCCGACGCGGCATGCGTGAACTTGATATCTCCATCATGCCTTT
CTTCGAATATGAGTATGACAGCTTAAGCGATGAGGATAAGCGTCTGTTTGTTCGCCTGCTTGAGTCTGACGATCCCGATT
TATTCAACTGGCTGATGAACCACGGCAAGCCCGCCGACACCGAGTTGCAACGGATGGTGCAATTAATTCAAACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References