Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 1799503..1800228 Replicon chromosome
Accession NZ_CP090594
Organism Pectobacterium aroidearum strain QJ034

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag L0Y22_RS08095 Protein ID WP_256543168.1
Coordinates 1799908..1800228 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag L0Y22_RS08090 Protein ID WP_193399492.1
Coordinates 1799503..1799838 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y22_RS08060 (L0Y22_08050) 1795123..1796154 + 1032 WP_011094394.1 hypothetical protein -
L0Y22_RS08065 (L0Y22_08055) 1796250..1797137 + 888 WP_256543166.1 50S ribosome-binding GTPase -
L0Y22_RS08070 (L0Y22_08060) 1797321..1797479 + 159 WP_155242703.1 hypothetical protein -
L0Y22_RS08075 (L0Y22_08065) 1797626..1798459 + 834 WP_256543167.1 hypothetical protein -
L0Y22_RS08080 (L0Y22_08070) 1798517..1798867 + 351 WP_005974477.1 hypothetical protein -
L0Y22_RS08085 (L0Y22_08075) 1798990..1799463 + 474 WP_193399491.1 DNA repair protein RadC -
L0Y22_RS08090 (L0Y22_08080) 1799503..1799838 + 336 WP_193399492.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
L0Y22_RS08095 (L0Y22_08085) 1799908..1800228 + 321 WP_256543168.1 TA system toxin CbtA family protein Toxin
L0Y22_RS08100 (L0Y22_08090) 1800346..1801179 + 834 WP_256543169.1 DUF4942 domain-containing protein -
L0Y22_RS08105 (L0Y22_08095) 1801302..1801499 + 198 WP_147387149.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
L0Y22_RS08110 (L0Y22_08100) 1802132..1802488 - 357 WP_181844695.1 hypothetical protein -
L0Y22_RS08115 (L0Y22_08105) 1802716..1802934 - 219 WP_180777774.1 KTSC domain-containing protein -
L0Y22_RS08120 (L0Y22_08110) 1803207..1804622 - 1416 WP_181848683.1 diguanylate cyclase -
L0Y22_RS08125 (L0Y22_08115) 1804833..1805036 + 204 WP_015840819.1 protein DsrB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - flhD / flhC / motA / motB / cheA / cheW / cheD / cheR / cheB / cheY / cheZ / flhB 1785450..1821191 35741


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 11922.66 Da        Isoelectric Point: 5.0492

>T231356 WP_256543168.1 NZ_CP090594:1799908-1800228 [Pectobacterium aroidearum]
MQTSPAIPPREDNPCASPVAVWQQLLTYLLEKHYGLTLNDTPFCEENVIQAHIDAGVTLVNAVNFLVEKYELVRIARDGF
NWQEQSPFLTAVDILRARRATGLLKA

Download         Length: 321 bp

>T231356 NZ_CP126341:c3015514-3015411 [Enterobacter cloacae]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12433.12 Da        Isoelectric Point: 5.1308

>AT231356 WP_193399492.1 NZ_CP090594:1799503-1799838 [Pectobacterium aroidearum]
MPSSDTPEWGLKCAITRRFGARLVQEGNRLHYLADRASIVGTFSKTEAQSLERCFPELIELLEQKLRMGELNPRQQGGVT
LYCNEWTCEADTLGSVGYVYIVIYPSSAATQ

Download         Length: 336 bp

>AT231356 NZ_CP126341:3015398-3015549 [Enterobacter cloacae]
CTTTCAATCAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGC
TAAAAGTTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTTTAAGAATAGATGACGACGCCAAGTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References