Detailed information of TA system TA231351

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): stbDE/ParE-DnaT
• Location: 4435492..4436023
• Replicon: chromosome
• Accession: NZ_CP090593
• Organism: Pectobacterium aroidearum strain QJ036

Toxin (Protein)

• Gene name: stbE
• Uniprot ID: -
• Locus tag: L0Y29_RS19855
• Protein ID: WP_256542520.1
• Coordinates: 4435492..4435779 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: stbD
• Uniprot ID: -
• Locus tag: L0Y29_RS19860
• Protein ID: WP_180778477.1
• Coordinates: 4435769..4436023 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L0Y29_RS19835 (L0Y29_19810)	4430806..4432197	+	1392	WP_181829970.1	outer membrane channel protein TolC	-
L0Y29_RS19840 (L0Y29_19815)	4432612..4433286	+	675	WP_012773030.1	DUF1190 family protein	-
L0Y29_RS19845 (L0Y29_19820)	4433298..4434458	+	1161	WP_180778474.1	glutathionylspermidine synthase family protein	-
L0Y29_RS19850 (L0Y29_19825)	4434528..4435313	-	786	WP_039524247.1	4,5-DOPA dioxygenase extradiol	-
L0Y29_RS19855 (L0Y29_19830)	4435492..4435779	-	288	WP_256542520.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
L0Y29_RS19860 (L0Y29_19835)	4435769..4436023	-	255	WP_180778477.1	plasmid stabilization protein	Antitoxin
L0Y29_RS19870 (L0Y29_19845)	4436911..4437798	-	888	WP_182100461.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
L0Y29_RS19875 (L0Y29_19850)	4437860..4439878	+	2019	WP_256542521.1	penicillin-binding protein activator	-
L0Y29_RS19880 (L0Y29_19855)	4439836..4440231	+	396	WP_180778506.1	YraN family protein	-
L0Y29_RS19885 (L0Y29_19860)	4440295..4440885	+	591	WP_012773024.1	DnaA initiator-associating protein DiaA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-78)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10967.91 Da
• Isoelectric Point: 10.7694

>T231351 WP_256542520.1 NZ_CP090593:c4435779-4435492 [Pectobacterium aroidearum]
MIYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGGGK
REGSQVYSDTKGRSA

Nucleotide

• Length: 288 bp

>T231351 NZ_CP126341:181762-181947 [Enterobacter cloacae]
GTGAAAAGTGCGGATGTCATTACTGTTCTGGTCAGGCATGGCTGGAAATGTGTAAGAACGAAAGTAAGCCATCATCAGTT
TCGCCACCCAGTACATGCGGGGTTGGTGACCGTTCCACATCCCAAAAAGGACATAAAACCCGGCACCCTCGCGCAAATCT
GGCGGCAGGCGGGAATCAAACACTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9240.44 Da
• Isoelectric Point: 3.7947

>AT231351 WP_180778477.1 NZ_CP090593:c4436023-4435769 [Pectobacterium aroidearum]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAMFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Nucleotide

• Length: 255 bp

>AT231351 NZ_CP126341:181962-182366 [Enterobacter cloacae]
ATGTTTTATCCGGCTTACATTCATTCTGATCCCGACGGTAGCGCCAGCGGTTTTTTTCCTGACGTTCCTGGTTGTTTTTT
TGCCGGCAATTCTCTGGATGATGCTTTTCAGGATGCACGTGATGCACTGACAGCTCACTTCGAAGCGCTATTTGAAATGG
ATGAAGAGTTACCTCTCCCTGGCAATGTTGAAGCACATCTTGAAGCCACACCGGGTGATTTTATCGGCGGACAATGGTTG
CTTGTAGATATCAATATGAAGCAATTCGACGGTAAGGCCGAGCGTATCAATATCACCCTGCCTCGTCGATTGCTGGTGAA
AATTGATTCTTTTGTGAGTGAGCATCCGCAGTTTAGTAACCGAAGCGCTTTTCTGGCTGAGGCAGCGCGTCGCGTGCTGC
CTTAA