Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 3067332..3068057 Replicon chromosome
Accession NZ_CP090592
Organism Pectobacterium aroidearum strain QJ311

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag L0Y27_RS13570 Protein ID WP_256598650.1
Coordinates 3067332..3067652 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag L0Y27_RS13575 Protein ID WP_256598651.1
Coordinates 3067722..3068057 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y27_RS13540 (L0Y27_13520) 3062630..3064045 + 1416 WP_181844696.1 diguanylate cyclase -
L0Y27_RS13545 (L0Y27_13525) 3064321..3064539 + 219 WP_015840821.1 KTSC domain-containing protein -
L0Y27_RS13550 (L0Y27_13530) 3064759..3065115 + 357 WP_256598647.1 hypothetical protein -
L0Y27_RS13555 (L0Y27_13535) 3065653..3066057 - 405 WP_256598648.1 tRNA(fMet)-specific endonuclease VapC -
L0Y27_RS13560 (L0Y27_13540) 3066057..3066287 - 231 WP_012765080.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
L0Y27_RS13565 (L0Y27_13545) 3066381..3067214 - 834 WP_256598649.1 DUF4942 domain-containing protein -
L0Y27_RS13570 (L0Y27_13550) 3067332..3067652 - 321 WP_256598650.1 TA system toxin CbtA family protein Toxin
L0Y27_RS13575 (L0Y27_13555) 3067722..3068057 - 336 WP_256598651.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
L0Y27_RS13580 (L0Y27_13560) 3068097..3068570 - 474 WP_256598652.1 DNA repair protein RadC -
L0Y27_RS13585 (L0Y27_13565) 3068693..3069043 - 351 WP_194430415.1 hypothetical protein -
L0Y27_RS13590 (L0Y27_13570) 3069101..3069934 - 834 WP_256598653.1 hypothetical protein -
L0Y27_RS13595 (L0Y27_13575) 3070081..3070239 - 159 WP_189654467.1 hypothetical protein -
L0Y27_RS13600 (L0Y27_13580) 3070423..3071310 - 888 WP_116238252.1 50S ribosome-binding GTPase -
L0Y27_RS13605 (L0Y27_13585) 3071406..3072437 - 1032 WP_011094394.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-106)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 11958.62 Da        Isoelectric Point: 4.5658

>T231338 WP_256598650.1 NZ_CP090592:c3067652-3067332 [Pectobacterium aroidearum]
MQATPAIPSGEDNPCPSPIAAWQQLLTYLMEKHYGLTLNDTPFCEENVIQEHIDAGITLVNAVNFLVEKYELVRIDRNGF
NWQEQSPFLTAVDVLRARRATGLLKT

Download         Length: 321 bp

>T231338 NZ_CP126338:3139719-3140288 [Proteus mirabilis]
ATGACAAACTATACTGTTTTGCTTGATGCCTGTGTCATGTATCCAGCCCCTCTTAGAAGTTATTTAATGTATCTTGCTAA
TACTGGTTTATTTAGAGCACGTTGGAGTAATCAGATCCATGATGAATGGATCACTAATTTATTAGTCAACAATCCAACAT
TAACAGCTGAGCGACTAATACGAACCAGAGATTTAATGAATGCACATGTTCCTGATTGTTTAGTAGAAGGCTACGAACCG
CTTATTTGTGGTTTAAAGCTACCTGATCCTAATGATCGTCATGTGCTAGCAGCAGCAATAAAAGGACAGGCTCAAGCTAT
AATTACATTTAACTTAAAAGATTTTCCGCAAAAATACCTTAATTCTTTTGATATTTCAGCTATCCATCCTGATGAATTTT
TGAGTGACATGTTTGAATTAAATCCTAGTAGCTGTATTAAAGCGGCGCAACAACATAGACAAAGCCTAAAGAATCCACCA
ATGACCGTAGAGACCTTTTTAGGCTGTTTACAAAAGCAGAAATTACCCCAGTTTATTTCCCATTTACGGGCATTCCAGAT
ATTATTATAA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12465.19 Da        Isoelectric Point: 6.2099

>AT231338 WP_256598651.1 NZ_CP090592:c3068057-3067722 [Pectobacterium aroidearum]
MSSVEAPEWGLKCAVTPRFGARLVQEGHRLHYLEDRASIVGTFSKTEARNLERCFPELIKQLEQKLRTGELNPCQQGCIV
LHCNEWTCEADTLGSFGYVYIAIYPSSAATQ

Download         Length: 336 bp

>AT231338 NZ_CP126338:3139267-3139719 [Proteus mirabilis]
ATGAATACGATAAGTGAGAGACTTAGTGCTGAAGATATTGCATTAGCAAAATTAAGTAGCCAAGAGCTATCCGCTGTTAT
GGATATTAATGGCAAAACGCAGAAGCTATCCATTATAGATAAGACGGGTAATAATCATATTGTACAAATACCAAATAGTG
CATTACGCCTAATGATTGAAATTCTTACTCAACTAGGGCAAGGGAATACTGTTAGTATCACACCAATCCATGCTGAGCTA
ACGACACAGGAAGCGGCTGATATACTCAATATGTCCCGTCCTACATTTGTAAAATTATTAGATACACGAGCGATACCCTA
CTCTAGAAAAGGAAATCGTAGGAAAGTTGCTTATGCTGATATTGTTGCTTATAAAAATGAATTGGAGCAAAAACGACTTG
ATGCCCTTGCTGAATTATCGCAATTAGATCAAGAAATGGATATGGGGTATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References