231328

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-DnaT
Location 4435492..4436023 Replicon chromosome
Accession NZ_CP090591
Organism Pectobacterium aroidearum strain QJ313

Toxin (Protein)


Gene name stbE Uniprot ID -
Locus tag L0Y30_RS19855 Protein ID WP_256542520.1
Coordinates 4435492..4435779 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID -
Locus tag L0Y30_RS19860 Protein ID WP_180778477.1
Coordinates 4435769..4436023 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y30_RS19835 (L0Y30_19810) 4430806..4432197 + 1392 WP_181829970.1 outer membrane channel protein TolC -
L0Y30_RS19840 (L0Y30_19815) 4432612..4433286 + 675 WP_012773030.1 DUF1190 family protein -
L0Y30_RS19845 (L0Y30_19820) 4433298..4434458 + 1161 WP_180778474.1 glutathionylspermidine synthase family protein -
L0Y30_RS19850 (L0Y30_19825) 4434528..4435313 - 786 WP_039524247.1 4,5-DOPA dioxygenase extradiol -
L0Y30_RS19855 (L0Y30_19830) 4435492..4435779 - 288 WP_256542520.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L0Y30_RS19860 (L0Y30_19835) 4435769..4436023 - 255 WP_180778477.1 plasmid stabilization protein Antitoxin
L0Y30_RS19870 (L0Y30_19845) 4436911..4437798 - 888 WP_182100461.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
L0Y30_RS19875 (L0Y30_19850) 4437860..4439878 + 2019 WP_256542521.1 penicillin-binding protein activator -
L0Y30_RS19880 (L0Y30_19855) 4439836..4440231 + 396 WP_180778506.1 YraN family protein -
L0Y30_RS19885 (L0Y30_19860) 4440295..4440885 + 591 WP_012773024.1 DnaA initiator-associating protein DiaA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-78)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10967.91 Da        Isoelectric Point: 10.7694

>T231328 WP_256542520.1 NZ_CP090591:c4435779-4435492 [Pectobacterium aroidearum]
MIYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGGGK
REGSQVYSDTKGRSA

Download         Length: 288 bp

>T231328 NZ_CP126335:2555578-2556063 [Proteus vulgaris]
ATGGGAAAAATAACAGCACCTGAGCCGTTATCAAATTCACATGAAGTGGCTGATTTTTATAGTAGTGAAAATGTATTAGA
TAACTGGATCAAACAAAGAGGTTTAAAAAACCAATTTTTAGGTGCATCCCGTACATTTATGGTCTGTGAAAAAAATAAAA
AACGTGTTGTTGGGTACTATTCTTTAGCAACAGGCAGTGTTAACCATACTGAAGCAATTAGTCATATTCGTCACAATATG
CCAGACCCAATACCCGTGATCATTTTAGCTAGACTTGCTGTTGATAAAACTTTTCATGGAAAAGGTCTTGGTGCCGATTT
GTTAAGAGATGCTGTTTTGCGTTGTCATCATGTAGCTGAAAACATTGGTGTTAGAGCGATTATGGTTCATGCACTCACAG
AAAATGCAAAACAGTTCTATCTTCACAATGGTTTTAAAGCTTCATCAACTCAAGAAAACACCTTATTTCTAGCATTAAAA
AAATAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9240.44 Da        Isoelectric Point: 3.7947

>AT231328 WP_180778477.1 NZ_CP090591:c4436023-4435769 [Pectobacterium aroidearum]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAMFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Download         Length: 255 bp

>AT231328 NZ_CP126335:2555324-2555590 [Proteus vulgaris]
ATGAAAGCTGATGTACAACTCAATATTCGCGCTAAAGGATCACAACGCGCACTTATTGATACTGCTGCTGAAATTCTCCA
TAAATCTCGTACTGACTTTATTCTTGAGACAGCATGCCAAGCTGCTGAAGACGTCATTTTAGACCGTAGAACCTTTAATT
TAAATGATGCTCAATATGCGGAATTTATAGAAATTATTGATGCGCCGGTTGATATTGACCCTGCTCTTGAAAAGTTATTA
ATGAGAAAACCATTATGGGAAAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References