Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mosAT/AbiEii-AbiEi |
Location | 4216554..4218252 | Replicon | chromosome |
Accession | NZ_CP090591 | ||
Organism | Pectobacterium aroidearum strain QJ313 |
Toxin (Protein)
Gene name | mosT | Uniprot ID | - |
Locus tag | L0Y30_RS18910 | Protein ID | WP_256542451.1 |
Coordinates | 4217323..4218252 (+) | Length | 310 a.a. |
Antitoxin (Protein)
Gene name | mosA | Uniprot ID | - |
Locus tag | L0Y30_RS18905 | Protein ID | WP_256542450.1 |
Coordinates | 4216554..4217336 (+) | Length | 261 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
L0Y30_RS18865 (L0Y30_18840) | 4211564..4211824 | + | 261 | WP_256542445.1 | helix-turn-helix transcriptional regulator | - |
L0Y30_RS18870 (L0Y30_18845) | 4212290..4214140 | + | 1851 | WP_256542446.1 | endonuclease NucS | - |
L0Y30_RS18875 (L0Y30_18850) | 4214382..4214579 | + | 198 | WP_256542447.1 | hypothetical protein | - |
L0Y30_RS18880 (L0Y30_18855) | 4214708..4214950 | - | 243 | WP_256542448.1 | helix-turn-helix transcriptional regulator | - |
L0Y30_RS18885 (L0Y30_18860) | 4215054..4215308 | + | 255 | WP_225181522.1 | helix-turn-helix transcriptional regulator | - |
L0Y30_RS18890 (L0Y30_18865) | 4215394..4215642 | + | 249 | WP_225181523.1 | helix-turn-helix transcriptional regulator | - |
L0Y30_RS18895 (L0Y30_18870) | 4215657..4215859 | + | 203 | Protein_3693 | type II toxin-antitoxin system antitoxin CcdA | - |
L0Y30_RS18900 (L0Y30_18875) | 4216019..4216336 | + | 318 | WP_256542449.1 | hypothetical protein | - |
L0Y30_RS18905 (L0Y30_18880) | 4216554..4217336 | + | 783 | WP_256542450.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
L0Y30_RS18910 (L0Y30_18885) | 4217323..4218252 | + | 930 | WP_256542451.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
L0Y30_RS18915 (L0Y30_18890) | 4218636..4219538 | - | 903 | WP_181847077.1 | LysR family transcriptional regulator | - |
L0Y30_RS18920 (L0Y30_18895) | 4219667..4219930 | + | 264 | WP_012773200.1 | DUF2798 domain-containing protein | - |
L0Y30_RS18925 (L0Y30_18900) | 4220096..4220479 | - | 384 | Protein_3699 | MBL fold metallo-hydrolase | - |
L0Y30_RS18930 (L0Y30_18905) | 4220452..4221162 | - | 711 | WP_256543452.1 | thiamine pyrophosphate-binding protein | - |
L0Y30_RS18935 (L0Y30_18910) | 4221441..4222373 | - | 933 | WP_256542452.1 | phosphoenolpyruvate mutase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 310 a.a. Molecular weight: 35068.40 Da Isoelectric Point: 5.9092
>T231326 WP_256542451.1 NZ_CP090591:4217323-4218252 [Pectobacterium aroidearum]
MDHRDIYARQVKLLMTALPYVAKEPCFALKGGTAINLFVQDFPRLSVDIDLVYQTFIDRDTDLIAIDDALMRITESLNGR
QGLTAIQQENKADEKRIIVNTADAQIKIEVSPVWRGLLLPPAEMPVCEQVEMEYGFTTMSVVSLADLYGGKICAALDRQH
PRDLFDVLNMLEKPCLTREIFDGFLCYLAGHPRPIAELLAPNWDTSRIATLYAQEFSGMTQQETSLESLLSVATLLPQAL
KSHFTAQDRQFLLSYKQNNPDWSLYRYPDIQHLPAIRWKQRNLSALHAKNPAKFSAAVGKLEKVLEQHF
MDHRDIYARQVKLLMTALPYVAKEPCFALKGGTAINLFVQDFPRLSVDIDLVYQTFIDRDTDLIAIDDALMRITESLNGR
QGLTAIQQENKADEKRIIVNTADAQIKIEVSPVWRGLLLPPAEMPVCEQVEMEYGFTTMSVVSLADLYGGKICAALDRQH
PRDLFDVLNMLEKPCLTREIFDGFLCYLAGHPRPIAELLAPNWDTSRIATLYAQEFSGMTQQETSLESLLSVATLLPQAL
KSHFTAQDRQFLLSYKQNNPDWSLYRYPDIQHLPAIRWKQRNLSALHAKNPAKFSAAVGKLEKVLEQHF
Download Length: 930 bp
>T231326 NZ_CP126335:c12649-12269 [Proteus vulgaris]
ATGAATTGGGTAAGTGCGAAAGAAGTTATTGCTTTTCATGATAAGATCTTAAAGCAACTTCCTGGTGTTGCAGGAATGTC
TGAACCAGGAAGAGCCGAAGCACTTATTTACAGAGTACAAAATCGTACTCATTATGAAGGCATAACAGATATTTATGAGT
TAGCTGCAACCTATTGGATCGCCATTTCTCGAGGTCATATTTTTAATGATGGTAATAAGCGAACTGCCTTTTTTGTCACT
ATGACTTTTCTTTATCGCAATGGTATAAAAATAATAGATATTGATGATACGCTGGAAAATTTAACCGTTGATGCAGCCAC
TGGAGCTAAAAATAGCCAACAGTTAGCACAATACCTAAGAAAATTAAGTGATAAAGACTAA
ATGAATTGGGTAAGTGCGAAAGAAGTTATTGCTTTTCATGATAAGATCTTAAAGCAACTTCCTGGTGTTGCAGGAATGTC
TGAACCAGGAAGAGCCGAAGCACTTATTTACAGAGTACAAAATCGTACTCATTATGAAGGCATAACAGATATTTATGAGT
TAGCTGCAACCTATTGGATCGCCATTTCTCGAGGTCATATTTTTAATGATGGTAATAAGCGAACTGCCTTTTTTGTCACT
ATGACTTTTCTTTATCGCAATGGTATAAAAATAATAGATATTGATGATACGCTGGAAAATTTAACCGTTGATGCAGCCAC
TGGAGCTAAAAATAGCCAACAGTTAGCACAATACCTAAGAAAATTAAGTGATAAAGACTAA
Antitoxin
Download Length: 261 a.a. Molecular weight: 29347.66 Da Isoelectric Point: 9.0688
>AT231326 WP_256542450.1 NZ_CP090591:4216554-4217336 [Pectobacterium aroidearum]
MTNYLNWLMQNTLPGQVLLQSWLTRNGIDRKLSYVYVQNGWLRRIAHGVYCRTGREPDWVDAVYCLQTQWEKPVRVAGLT
SLALQGYSHYTELGKPQIWLTLPAYIKLPGWFTAFKPSATFVVLYTSGLSVDVMPLTTELRIGDRRLTGSMPELAAYEIA
SGVPAQISFEHADALFQGLNLLSPRKLQALLYASHSVKTNRVMLYLAQRNGHPYFQYLDKSGIETGAGKRQIVPGGWLEP
DYQITVPREFKSEGVEDGSS
MTNYLNWLMQNTLPGQVLLQSWLTRNGIDRKLSYVYVQNGWLRRIAHGVYCRTGREPDWVDAVYCLQTQWEKPVRVAGLT
SLALQGYSHYTELGKPQIWLTLPAYIKLPGWFTAFKPSATFVVLYTSGLSVDVMPLTTELRIGDRRLTGSMPELAAYEIA
SGVPAQISFEHADALFQGLNLLSPRKLQALLYASHSVKTNRVMLYLAQRNGHPYFQYLDKSGIETGAGKRQIVPGGWLEP
DYQITVPREFKSEGVEDGSS
Download Length: 783 bp
>AT231326 NZ_CP126335:c12867-12646 [Proteus vulgaris]
ATGCATACTTATACCTCGACTCAAGCTAGGGCTCATATTTCTGAAGTTTTAGACACCGCTATTCATGGTGAGCCTGTAGA
AATAACCCGCAGAGATGGTACATCAGCCGTAGTTATTAGTAAGGTTGAATTTGAAGCCTACCAAAACGCAAAACTAGATG
CTGAATTCGATATCATTATGCAACGTCATGGGCATACAATAAAGGCATTAACAAACCGATGA
ATGCATACTTATACCTCGACTCAAGCTAGGGCTCATATTTCTGAAGTTTTAGACACCGCTATTCATGGTGAGCCTGTAGA
AATAACCCGCAGAGATGGTACATCAGCCGTAGTTATTAGTAAGGTTGAATTTGAAGCCTACCAAAACGCAAAACTAGATG
CTGAATTCGATATCATTATGCAACGTCATGGGCATACAATAAAGGCATTAACAAACCGATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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