Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3972176..3972836 Replicon chromosome
Accession NZ_CP090591
Organism Pectobacterium aroidearum strain QJ313

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag L0Y30_RS17705 Protein ID WP_043881709.1
Coordinates 3972176..3972550 (-) Length 125 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID C6D8Y5
Locus tag L0Y30_RS17710 Protein ID WP_012773340.1
Coordinates 3972570..3972836 (-) Length 89 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y30_RS17680 (L0Y30_17655) 3967553..3968452 - 900 WP_012773347.1 site-specific tyrosine recombinase XerD -
L0Y30_RS17685 (L0Y30_17660) 3968764..3970092 + 1329 WP_181845156.1 MFS transporter -
L0Y30_RS17690 (L0Y30_17665) 3970255..3970773 + 519 WP_012773344.1 flavodoxin FldB -
L0Y30_RS17695 (L0Y30_17670) 3970802..3971125 + 324 WP_180777498.1 hypothetical protein -
L0Y30_RS17700 (L0Y30_17675) 3971171..3972106 - 936 WP_256542328.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
L0Y30_RS17705 (L0Y30_17680) 3972176..3972550 - 375 WP_043881709.1 protein YgfX Toxin
L0Y30_RS17710 (L0Y30_17685) 3972570..3972836 - 267 WP_012773340.1 FAD assembly factor SdhE Antitoxin
L0Y30_RS17715 (L0Y30_17690) 3973072..3974073 + 1002 WP_256542329.1 tRNA-modifying protein YgfZ -
L0Y30_RS17720 (L0Y30_17695) 3974253..3974900 - 648 WP_012773338.1 hemolysin III family protein -
L0Y30_RS17725 (L0Y30_17700) 3975313..3975921 + 609 WP_181829659.1 HD domain-containing protein -
L0Y30_RS17730 (L0Y30_17705) 3975965..3976969 + 1005 WP_256542330.1 LacI family DNA-binding transcriptional regulator -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(2-119)

Antitoxin

(8-79)


Sequences


Toxin        


Download         Length: 125 a.a.        Molecular weight: 14673.34 Da        Isoelectric Point: 10.6585

>T231325 WP_043881709.1 NZ_CP090591:c3972550-3972176 [Pectobacterium aroidearum]
MQLLSLIVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQEWQIVKRPWLLKN
GVLLSLQAVNGKDRQQLWLASDSMGDDEWRHLRQLLLQQKNWAR

Download         Length: 375 bp

>T231325 NZ_CP126333:39623-40039 [Citrobacter braakii]
ATGAAGAAAACCTGGATGCTCGACACCAACATCTGCTCGTTCATCATGCGCGAGCAGCCGGCAGCGGTGCTGAAGCGCCT
GGAGCAGGCGGTGCTGCGCGGTGATCGCATTGTGGTCTCGGCCGTGACGTATGCCGAGATGCGCTTCGGCGCCACCGGCC
CGAAGGCCTCGCCGCGCCATATTCAGCTGGTCGACGCGTTCTGCGCGCGCCTCGATGCCGTCCTGCCCTGGGACCGCGCC
GCGGTGGACGCCACGACGGACATCCGGGTGGCGCTGCGCCTAGCCGGGACGCCGATCGGCCCGAATGACACGGCCATTGC
CGGGCACGCCATCGCGGCGGGCGCCATCCTGGTGACGAACAATGTGAGAGAGTTTGCGCGGGTCCCGGGCCTGGTGCTGG
AAGACTGGGTGAAATAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10465.94 Da        Isoelectric Point: 6.2223

>AT231325 WP_012773340.1 NZ_CP090591:c3972836-3972570 [Pectobacterium aroidearum]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLSDSDKRTFVRLLQSDDPDLFNWLMNHGEPKDGELKRMISLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT231325 NZ_CP126333:39396-39626 [Citrobacter braakii]
ATGCGCACAGTTTCGATATTTAAAAACGGCAATAACCGCGCCATCCGTCTGCCCCGGGACCTGGATTTTGATGGCGTCAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATCATTCTGCGTCCCGTCCGGCCGACCTGGGGCTCGTTCGCGCAGCTGG
ACAGGGCCGATCCGGACTTTATGGCGGAGCGTGAGGATGTGGTCAGCGATGAAGGACGCTTTGAGCCATGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A7W2E501

References