Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | ccdAB/CcdA(antitoxin) |
Location | 3768926..3769452 | Replicon | chromosome |
Accession | NZ_CP090591 | ||
Organism | Pectobacterium aroidearum strain QJ313 |
Toxin (Protein)
Gene name | ccdB | Uniprot ID | - |
Locus tag | L0Y30_RS16830 | Protein ID | WP_256542272.1 |
Coordinates | 3769147..3769452 (+) | Length | 102 a.a. |
Antitoxin (Protein)
Gene name | ccdA | Uniprot ID | - |
Locus tag | L0Y30_RS16825 | Protein ID | WP_198482245.1 |
Coordinates | 3768926..3769144 (+) | Length | 73 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
L0Y30_RS16795 | 3764300..3764431 | - | 132 | WP_256542269.1 | hypothetical protein | - |
L0Y30_RS16805 (L0Y30_16780) | 3765178..3766437 | + | 1260 | WP_256542270.1 | integrase arm-type DNA-binding domain-containing protein | - |
L0Y30_RS16810 (L0Y30_16785) | 3766582..3766752 | - | 171 | WP_164669135.1 | hypothetical protein | - |
L0Y30_RS16815 (L0Y30_16790) | 3766893..3767234 | + | 342 | WP_256542271.1 | hypothetical protein | - |
L0Y30_RS16820 (L0Y30_16795) | 3768124..3768867 | + | 744 | WP_198482246.1 | MobC family replication-relaxation protein | - |
L0Y30_RS16825 (L0Y30_16800) | 3768926..3769144 | + | 219 | WP_198482245.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin |
L0Y30_RS16830 (L0Y30_16805) | 3769147..3769452 | + | 306 | WP_256542272.1 | type II toxin-antitoxin system toxin CcdB | Toxin |
L0Y30_RS16835 (L0Y30_16810) | 3769837..3770880 | - | 1044 | WP_256542273.1 | DUF4435 domain-containing protein | - |
L0Y30_RS16840 (L0Y30_16815) | 3771081..3772532 | - | 1452 | WP_256542274.1 | hypothetical protein | - |
L0Y30_RS16845 (L0Y30_16820) | 3773004..3773216 | - | 213 | WP_256542275.1 | hypothetical protein | - |
L0Y30_RS16850 (L0Y30_16825) | 3773542..3773784 | - | 243 | WP_205947008.1 | helix-turn-helix transcriptional regulator | - |
L0Y30_RS16855 (L0Y30_16830) | 3773888..3774142 | + | 255 | WP_039285388.1 | helix-turn-helix transcriptional regulator | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Integrative and Conjugative Element | - | - | 3765001..3773453 | 8452 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 102 a.a. Molecular weight: 11690.53 Da Isoelectric Point: 4.6761
>T231323 WP_256542272.1 NZ_CP090591:3769147-3769452 [Pectobacterium aroidearum]
MQFIVYEYKRASHYKMFVDVQSDIVDTPKRRMVIPLIEAHHLSEKVNKTLFPLIRIDGEDYRLMTTELSSVPVEVIGEAI
ADLGDYADEVKDAINLMFWGI
MQFIVYEYKRASHYKMFVDVQSDIVDTPKRRMVIPLIEAHHLSEKVNKTLFPLIRIDGEDYRLMTTELSSVPVEVIGEAI
ADLGDYADEVKDAINLMFWGI
Download Length: 306 bp
>T231323 NZ_CP126331:c19299-19015 [Citrobacter braakii]
GTGTATAAACTCACCGAACGGGCGGCAGAAGACTTCGCCGGGATTTATGATTATACGCTCTTGAAATTTGGTGAAGCTCA
GGCAGACCATTATACCGACGCACTTGAGGCATTTTTCGAGACACTGGCCGGAATGCCAGATATGGGACGTGACTACCATG
CCGTTCCTGGTGTAATGCGCATTGAATTTCAGCGACATGCCATTTTTTATACGGTTCGTGATACGGATATTCTGATTGCG
CGTATTTTGCACCAACAGATGAACCATAAACGCCATTTACTGTAA
GTGTATAAACTCACCGAACGGGCGGCAGAAGACTTCGCCGGGATTTATGATTATACGCTCTTGAAATTTGGTGAAGCTCA
GGCAGACCATTATACCGACGCACTTGAGGCATTTTTCGAGACACTGGCCGGAATGCCAGATATGGGACGTGACTACCATG
CCGTTCCTGGTGTAATGCGCATTGAATTTCAGCGACATGCCATTTTTTATACGGTTCGTGATACGGATATTCTGATTGCG
CGTATTTTGCACCAACAGATGAACCATAAACGCCATTTACTGTAA
Antitoxin
Download Length: 73 a.a. Molecular weight: 8174.14 Da Isoelectric Point: 7.2038
>AT231323 WP_198482245.1 NZ_CP090591:3768926-3769144 [Pectobacterium aroidearum]
MKHRVSVTVDKDSYQVLSAAGVNISGLVNDAIGKEARRIKAEEWKKENREGMEEVARFIAQHGSFADENRNW
MKHRVSVTVDKDSYQVLSAAGVNISGLVNDAIGKEARRIKAEEWKKENREGMEEVARFIAQHGSFADENRNW
Download Length: 219 bp
>AT231323 NZ_CP126331:c19534-19292 [Citrobacter braakii]
ATGGCCAGAACAACAAGCGTTACGATTGGCGAACAACTCGATTCGTTTATCAGTCGATTAATAGACAGTGGCCGTTACGG
CTCTGCAAGTGAAGTTATGCGCTCTGCGCTGCGATTGCTGGAGCAACAGGAAACAAACGATGAAGTTATTCGCCAGGCTG
TTATTACCGGGCTGGAAAGCGGTGAAAGCTCGCTATCACTGCGGGATATTGCAGCAGAAAGAAAACTGAGACATCGTGTA
TAA
ATGGCCAGAACAACAAGCGTTACGATTGGCGAACAACTCGATTCGTTTATCAGTCGATTAATAGACAGTGGCCGTTACGG
CTCTGCAAGTGAAGTTATGCGCTCTGCGCTGCGATTGCTGGAGCAACAGGAAACAAACGATGAAGTTATTCGCCAGGCTG
TTATTACCGGGCTGGAAAGCGGTGAAAGCTCGCTATCACTGCGGGATATTGCAGCAGAAAGAAAACTGAGACATCGTGTA
TAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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