Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | Hha-TomB/- |
Location | 3533897..3534522 | Replicon | chromosome |
Accession | NZ_CP090591 | ||
Organism | Pectobacterium aroidearum strain QJ313 |
Toxin (Protein)
Gene name | Hha | Uniprot ID | C6DB72 |
Locus tag | L0Y30_RS15830 | Protein ID | WP_005976087.1 |
Coordinates | 3534319..3534522 (+) | Length | 68 a.a. |
Antitoxin (Protein)
Gene name | TomB | Uniprot ID | C6DB73 |
Locus tag | L0Y30_RS15825 | Protein ID | WP_005976089.1 |
Coordinates | 3533897..3534265 (+) | Length | 123 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
L0Y30_RS15810 (L0Y30_15790) | 3529528..3532656 | + | 3129 | WP_015839362.1 | efflux RND transporter permease subunit | - |
L0Y30_RS15815 (L0Y30_15795) | 3532891..3533139 | + | 249 | WP_015839361.1 | type B 50S ribosomal protein L31 | - |
L0Y30_RS15820 (L0Y30_15800) | 3533157..3533300 | + | 144 | WP_005976091.1 | type B 50S ribosomal protein L36 | - |
L0Y30_RS15825 (L0Y30_15805) | 3533897..3534265 | + | 369 | WP_005976089.1 | Hha toxicity modulator TomB | Antitoxin |
L0Y30_RS15830 (L0Y30_15810) | 3534319..3534522 | + | 204 | WP_005976087.1 | HHA domain-containing protein | Toxin |
L0Y30_RS15840 (L0Y30_15820) | 3535269..3535589 | + | 321 | WP_015839360.1 | MGMT family protein | - |
L0Y30_RS15845 (L0Y30_15825) | 3535609..3536190 | - | 582 | WP_256542207.1 | YbaY family lipoprotein | - |
L0Y30_RS15850 (L0Y30_15830) | 3536403..3537266 | + | 864 | WP_015839358.1 | acyl-CoA thioesterase II | - |
L0Y30_RS15855 (L0Y30_15835) | 3537396..3538706 | + | 1311 | WP_225182003.1 | IS4 family transposase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | flank | IS/Tn | - | - | 3537396..3538706 | 1310 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 68 a.a. Molecular weight: 8145.52 Da Isoelectric Point: 8.9008
>T231322 WP_005976087.1 NZ_CP090591:3534319-3534522 [Pectobacterium aroidearum]
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFFSAADHRLAELTMNKLYDKVPTAVWRYVR
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFFSAADHRLAELTMNKLYDKVPTAVWRYVR
Download Length: 204 bp
>T231322 NZ_CP126330:36454-36741 [Citrobacter braakii]
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA
ATGGCGTATTTTCTGGATTTTGACGAGCGGGCACTAAAGGAATGGCGAAAGCTGGGCTCGACGGTACGTGAACAGTTGAA
AAAGAAGCTGGTTGAAGTACTTGAGTCACCCCGGATTGAAGCAAACAAGCTCCGTGGTATGCCTGATTGTTACAAGATTA
AGCTCCGGTCTTCAGGCTATCGCCTTGTATACCAGGTTATAGACGAGAAAGTTGTCGTTTTCGTGATTTCTGTTGGGAAA
AGAGAACGCTCGGAAGTATATAGCGAGGCGGTCAAACGCATTCTCTGA
Antitoxin
Download Length: 123 a.a. Molecular weight: 14032.77 Da Isoelectric Point: 4.4787
>AT231322 WP_005976089.1 NZ_CP090591:3533897-3534265 [Pectobacterium aroidearum]
MDEYTPKHYDIAQLRFLCENLCDESIATLGDSSHGWVNDPTSAINLQLNELIEHIATFILTFKIKYPNESELSEQVEKYL
DDTYVLFSNYGINDAELRRWQKSKAKLFGMFSGENVCTPAKT
MDEYTPKHYDIAQLRFLCENLCDESIATLGDSSHGWVNDPTSAINLQLNELIEHIATFILTFKIKYPNESELSEQVEKYL
DDTYVLFSNYGINDAELRRWQKSKAKLFGMFSGENVCTPAKT
Download Length: 369 bp
>AT231322 NZ_CP126330:36215-36454 [Citrobacter braakii]
ATGGGTAGCATTAACCTGCGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGCGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGGCTTCGTAAGCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA
ATGGGTAGCATTAACCTGCGTATTGACGATGAACTTAAAGCGCGTTCTTACGCCGCGCTTGAAAAAATGGGCGTAACTCC
TTCTGAAGCGCTTCGTCTCATGCTCGAGTATATCGCTGACAATGAACGCTTGCCGTTCAAACAGACACTCCTGAGTGATG
AAGATGCTGAACTTGTGGAGATAGTGAAAGAACGGCTTCGTAAGCCTAAGCCAGTACGTGTGACGCTGGATGAACTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1D7Z3F0 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1D7Z3G5 |