Detailed information of TA system TA231320

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ykfI-yfjZ/CbtA-CbeA
• Location: 1799503..1800228
• Replicon: chromosome
• Accession: NZ_CP090591
• Organism: Pectobacterium aroidearum strain QJ313

Toxin (Protein)

• Gene name: ykfI
• Uniprot ID: -
• Locus tag: L0Y30_RS08105
• Protein ID: WP_256543168.1
• Coordinates: 1799908..1800228 (+)
• Length: 107 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: L0Y30_RS08100
• Protein ID: WP_193399492.1
• Coordinates: 1799503..1799838 (+)
• Length: 112 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L0Y30_RS08070 (L0Y30_08060)	1795123..1796154	+	1032	WP_011094394.1	hypothetical protein	-
L0Y30_RS08075 (L0Y30_08065)	1796250..1797137	+	888	WP_256543166.1	50S ribosome-binding GTPase	-
L0Y30_RS08080 (L0Y30_08070)	1797321..1797479	+	159	WP_155242703.1	hypothetical protein	-
L0Y30_RS08085 (L0Y30_08075)	1797626..1798459	+	834	WP_256543167.1	hypothetical protein	-
L0Y30_RS08090 (L0Y30_08080)	1798517..1798867	+	351	WP_005974477.1	hypothetical protein	-
L0Y30_RS08095 (L0Y30_08085)	1798990..1799463	+	474	WP_193399491.1	DNA repair protein RadC	-
L0Y30_RS08100 (L0Y30_08090)	1799503..1799838	+	336	WP_193399492.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
L0Y30_RS08105 (L0Y30_08095)	1799908..1800228	+	321	WP_256543168.1	TA system toxin CbtA family protein	Toxin
L0Y30_RS08110 (L0Y30_08100)	1800346..1801179	+	834	WP_256543169.1	DUF4942 domain-containing protein	-
L0Y30_RS08115 (L0Y30_08105)	1801302..1801499	+	198	WP_147387149.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	-
L0Y30_RS08120 (L0Y30_08110)	1802132..1802488	-	357	WP_181844695.1	hypothetical protein	-
L0Y30_RS08125 (L0Y30_08115)	1802716..1802934	-	219	WP_180777774.1	KTSC domain-containing protein	-
L0Y30_RS08130 (L0Y30_08120)	1803207..1804622	-	1416	WP_181848683.1	diguanylate cyclase	-
L0Y30_RS08135 (L0Y30_08125)	1804833..1805036	+	204	WP_015840819.1	protein DsrB	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	flhD / flhC / motA / motB / cheA / cheW / cheD / cheR / cheB / cheY / cheZ / flhB	1785450..1821191	35741

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-105)

Antitoxin

• Antitoxin CbeA (7-106)

Sequences

Toxin

Protein

• Length: 107 a.a.
• Molecular weight: 11922.66 Da
• Isoelectric Point: 5.0492

>T231320 WP_256543168.1 NZ_CP090591:1799908-1800228 [Pectobacterium aroidearum]
MQTSPAIPPREDNPCASPVAVWQQLLTYLLEKHYGLTLNDTPFCEENVIQAHIDAGVTLVNAVNFLVEKYELVRIARDGF
NWQEQSPFLTAVDILRARRATGLLKA

Nucleotide

• Length: 321 bp

>T231320 NZ_CP126329:c4516766-4516392 [Citrobacter braakii]
ATGGTCACAGGATCTGCGCTTTTTGATACCAACATCCTCATCGACCTGTTTAGCGGGCGAAGTGAAGCAAAACTAGCGAT
AGAAACATGGCCGCCGCAGAACGCAATCAGCCTCATTACATGGATGGAGTTGATGGTGGGCGCAAAAAAATATCATCAGG
AATCTCGCACACGCGTTGCGCTAGGCGCTTTTAATGTGATCGGTGTTTCACAGGATATTGCTGAACGAAGCGTGAGTATC
AGGCAGGAATATGGGATGAAATTGCCGGATGCCATCATTTTGGCCACTGCGCAGATTCATCGTCTTACACTGGTTACGCG
TAATACCAGGGATTTTGCAGGCATATCCGGCGTGGTCACACCGTATACGTTATAA

Antitoxin

Protein

• Length: 112 a.a.
• Molecular weight: 12433.12 Da
• Isoelectric Point: 5.1308

>AT231320 WP_193399492.1 NZ_CP090591:1799503-1799838 [Pectobacterium aroidearum]
MPSSDTPEWGLKCAITRRFGARLVQEGNRLHYLADRASIVGTFSKTEAQSLERCFPELIELLEQKLRMGELNPRQQGGVT
LYCNEWTCEADTLGSVGYVYIVIYPSSAATQ

Nucleotide

• Length: 336 bp

>AT231320 NZ_CP126329:c4517008-4516766 [Citrobacter braakii]
ATGATGGCTGGGATGGATATGGGCAGAATTTTACTCGATTTATCAGACGAAGTGATCAAACGTCTTGATGATCTCAAGGT
GCAGCGTAATCTGCCGCGGGCCGAGCTTTTGCGGGAGGCTGTTGAACAGTATCTTGAGAGGCAGGATCAAGCTGAAACGA
CAATTTCACGTGCTCTTGGGCTATGGCAAGGTTGTGAGGAAGATGGCGTTGATTATCAGCGTAAACTCCGCGAGGAATGG
TAA