Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4725009..4725544 Replicon chromosome
Accession NZ_CP090590
Organism Pectobacterium aroidearum strain QJ315

Toxin (Protein)


Gene name relE Uniprot ID C6DJA0
Locus tag L0Y23_RS21240 Protein ID WP_015842269.1
Coordinates 4725257..4725544 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q6DB37
Locus tag L0Y23_RS21235 Protein ID WP_010281712.1
Coordinates 4725009..4725260 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y23_RS21205 (L0Y23_21185) 4720402..4720839 + 438 WP_256542605.1 RICIN domain-containing protein -
L0Y23_RS21210 (L0Y23_21190) 4721127..4721438 + 312 WP_256542606.1 LysR substrate-binding domain-containing protein -
L0Y23_RS21215 (L0Y23_21195) 4721480..4722103 - 624 WP_256542607.1 LysE family translocator -
L0Y23_RS21220 (L0Y23_21200) 4722285..4722989 + 705 WP_256542608.1 SMI1/KNR4 family protein -
L0Y23_RS21225 (L0Y23_21205) 4723059..4723814 + 756 WP_181845543.1 thiol:disulfide interchange protein DsbG -
L0Y23_RS21230 (L0Y23_21210) 4723849..4724754 - 906 WP_256542609.1 siderophore-interacting protein -
L0Y23_RS21235 (L0Y23_21215) 4725009..4725260 + 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
L0Y23_RS21240 (L0Y23_21220) 4725257..4725544 + 288 WP_015842269.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L0Y23_RS21245 (L0Y23_21225) 4725653..4727005 - 1353 WP_256542610.1 glutathione-disulfide reductase -
L0Y23_RS21250 (L0Y23_21230) 4727133..4727975 - 843 WP_015842271.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
L0Y23_RS21255 (L0Y23_21235) 4728194..4728922 + 729 WP_043881851.1 DUF1266 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11074.15 Da        Isoelectric Point: 10.3527

>T231316 WP_015842269.1 NZ_CP090590:4725257-4725544 [Pectobacterium aroidearum]
MSYSVKFREDALKEWLKLDKTIQQQFAKKLKKCCENPHIPSAKLRGMKDCYKIKLRASGFRLVYEVIDDVLIIAVVAVGK
RERSGVYHLASERMR

Download         Length: 288 bp

>T231316 NZ_CP126329:c2662140-2662037 [Citrobacter braakii]
GGCAGGGTAACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9117.47 Da        Isoelectric Point: 4.0637

>AT231316 WP_010281712.1 NZ_CP090590:4725009-4725260 [Pectobacterium aroidearum]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Download         Length: 252 bp

>AT231316 NZ_CP126329:2662037-2662175 [Citrobacter braakii]
AAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TAATGCAGGCTAAGTTACCCTGCCATTTAAGAATAGATGACAGCGCCAGGTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3S0XQ75

Antitoxin

Source ID Structure
AlphaFold DB A0A0M2EZP0

References