Detailed information of TA system TA231315

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): stbDE/ParE-DnaT
• Location: 4411652..4412183
• Replicon: chromosome
• Accession: NZ_CP090590
• Organism: Pectobacterium aroidearum strain QJ315

Toxin (Protein)

• Gene name: stbE
• Uniprot ID: -
• Locus tag: L0Y23_RS19730
• Protein ID: WP_256542520.1
• Coordinates: 4411652..4411939 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: stbD
• Uniprot ID: -
• Locus tag: L0Y23_RS19735
• Protein ID: WP_180778477.1
• Coordinates: 4411929..4412183 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L0Y23_RS19710 (L0Y23_19690)	4406966..4408357	+	1392	WP_181829970.1	outer membrane channel protein TolC	-
L0Y23_RS19715 (L0Y23_19695)	4408772..4409446	+	675	WP_012773030.1	DUF1190 family protein	-
L0Y23_RS19720 (L0Y23_19700)	4409458..4410618	+	1161	WP_180778474.1	glutathionylspermidine synthase family protein	-
L0Y23_RS19725 (L0Y23_19705)	4410688..4411473	-	786	WP_039524247.1	4,5-DOPA dioxygenase extradiol	-
L0Y23_RS19730 (L0Y23_19710)	4411652..4411939	-	288	WP_256542520.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
L0Y23_RS19735 (L0Y23_19715)	4411929..4412183	-	255	WP_180778477.1	plasmid stabilization protein	Antitoxin
L0Y23_RS19745 (L0Y23_19725)	4413071..4413958	-	888	WP_182100461.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
L0Y23_RS19750 (L0Y23_19730)	4414020..4416038	+	2019	WP_256542521.1	penicillin-binding protein activator	-
L0Y23_RS19755 (L0Y23_19735)	4415996..4416391	+	396	WP_180778506.1	YraN family protein	-
L0Y23_RS19760 (L0Y23_19740)	4416455..4417045	+	591	WP_012773024.1	DnaA initiator-associating protein DiaA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-78)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10967.91 Da
• Isoelectric Point: 10.7694

>T231315 WP_256542520.1 NZ_CP090590:c4411939-4411652 [Pectobacterium aroidearum]
MIYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMVMGGGK
REGSQVYSDTKGRSA

Nucleotide

• Length: 288 bp

>T231315 NZ_CP126329:2251268-2251456 [Citrobacter braakii]
GTGAAGCAAAGTGAGTTCAGACGCTGGCTTGAATCTCAGGGAGTGGCTGTTACAAACGGCTCAAATCATCTGAAGTTGAG
GTATCAGGGAAGGCGTAGCGTTATGCCCAGGCATCCTGGTGATGAAATAAAAGAAGCCTTGCGAAAATCGATCCTGAAGC
AGCTTGGTTTACAGTCATCATCAATATGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9240.44 Da
• Isoelectric Point: 3.7947

>AT231315 WP_180778477.1 NZ_CP090590:c4412183-4411929 [Pectobacterium aroidearum]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAMFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Nucleotide

• Length: 255 bp

>AT231315 NZ_CP126329:2251488-2251904 [Citrobacter braakii]
ATGCGTTATCCCGTTAATCTAATCCCCGCCGTGGAAGGTGGATTCGTGGTTTCTTTCCCGGATATTCCTGAAGCATTAAC
CCAGGGCGAAACCCGTCATGGGGCTTTGCAGGCTGCGCAGTCTGCATTGGTGACCGCTTTTGAATTCTATTTCGACGATA
ACGAACCGATTCCTTTACCTTCGGCGGTTGGCACTGAAGGTGACTATGTGGAAATCCCCCTGAGCATTGCGTCGAAGGTT
CTTTTGTTAAATGCCTTTCTTGAATCAAAAATCACCCAGCAGGAGCTGGCAAACAGGATTGGCAGGCCTAAGCAGGAAAT
TACCCGTTTGTTCGATTTAAAGCACGCGACAAAAATTGATGCTGTGCAAATAGCTGCACGCGCCTTAGGCAAGGAGCTGT
CAGTAACGATGTTGTAA