Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 4192714..4194412 Replicon chromosome
Accession NZ_CP090590
Organism Pectobacterium aroidearum strain QJ315

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag L0Y23_RS18785 Protein ID WP_256542451.1
Coordinates 4193483..4194412 (+) Length 310 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag L0Y23_RS18780 Protein ID WP_256542450.1
Coordinates 4192714..4193496 (+) Length 261 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y23_RS18740 (L0Y23_18720) 4187724..4187984 + 261 WP_256542445.1 helix-turn-helix transcriptional regulator -
L0Y23_RS18745 (L0Y23_18725) 4188450..4190300 + 1851 WP_256542446.1 endonuclease NucS -
L0Y23_RS18750 (L0Y23_18730) 4190542..4190739 + 198 WP_256542447.1 hypothetical protein -
L0Y23_RS18755 (L0Y23_18735) 4190868..4191110 - 243 WP_256542448.1 helix-turn-helix transcriptional regulator -
L0Y23_RS18760 (L0Y23_18740) 4191214..4191468 + 255 WP_225181522.1 helix-turn-helix transcriptional regulator -
L0Y23_RS18765 (L0Y23_18745) 4191554..4191802 + 249 WP_225181523.1 helix-turn-helix transcriptional regulator -
L0Y23_RS18770 (L0Y23_18750) 4191817..4192019 + 203 Protein_3670 type II toxin-antitoxin system antitoxin CcdA -
L0Y23_RS18775 (L0Y23_18755) 4192179..4192496 + 318 WP_256542449.1 hypothetical protein -
L0Y23_RS18780 (L0Y23_18760) 4192714..4193496 + 783 WP_256542450.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
L0Y23_RS18785 (L0Y23_18765) 4193483..4194412 + 930 WP_256542451.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
L0Y23_RS18790 (L0Y23_18770) 4194796..4195698 - 903 WP_181847077.1 LysR family transcriptional regulator -
L0Y23_RS18795 (L0Y23_18775) 4195827..4196090 + 264 WP_012773200.1 DUF2798 domain-containing protein -
L0Y23_RS18800 (L0Y23_18780) 4196256..4196639 - 384 Protein_3676 MBL fold metallo-hydrolase -
L0Y23_RS18805 (L0Y23_18785) 4196612..4197322 - 711 WP_256543452.1 thiamine pyrophosphate-binding protein -
L0Y23_RS18810 (L0Y23_18790) 4197601..4198533 - 933 WP_256542452.1 phosphoenolpyruvate mutase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(14-261)

Antitoxin

Transcriptional regulator, AbiEi 3 antitoxin, Type IV TA system

(95-247)


Sequences

Toxin        


Download         Length: 310 a.a.        Molecular weight: 35068.40 Da        Isoelectric Point: 5.9092

>T231313 WP_256542451.1 NZ_CP090590:4193483-4194412 [Pectobacterium aroidearum]
MDHRDIYARQVKLLMTALPYVAKEPCFALKGGTAINLFVQDFPRLSVDIDLVYQTFIDRDTDLIAIDDALMRITESLNGR
QGLTAIQQENKADEKRIIVNTADAQIKIEVSPVWRGLLLPPAEMPVCEQVEMEYGFTTMSVVSLADLYGGKICAALDRQH
PRDLFDVLNMLEKPCLTREIFDGFLCYLAGHPRPIAELLAPNWDTSRIATLYAQEFSGMTQQETSLESLLSVATLLPQAL
KSHFTAQDRQFLLSYKQNNPDWSLYRYPDIQHLPAIRWKQRNLSALHAKNPAKFSAAVGKLEKVLEQHF

Download         Length: 930 bp

>T231313 NZ_CP126326:70079-70357 [Salmonella enterica subsp. enterica]
ATGGAGATTTTCTGGACCATGCTGGCCAGTCAGGACAGAAAGCGTATTCGCGAGTACATTGCAGAACAAAATCTGATGGC
TGCTGTTGCACTTGACGAACAGATTAGCGATTCAGCCGGCAGCTTGGCTGAACAACCGTATAAAGGACGTTACGGTCGGG
CTGAAGATACCCGGGAACTGGTCATCCACCCACATTTTGTTCTCGTTTATGAAGTGGATAAACAATGGGGGAAAGTGTAT
ATCCTGCGTGTATTACATACTGCGCAGAAGTGGCCATGA

Antitoxin


Download         Length: 261 a.a.        Molecular weight: 29347.66 Da        Isoelectric Point: 9.0688

>AT231313 WP_256542450.1 NZ_CP090590:4192714-4193496 [Pectobacterium aroidearum]
MTNYLNWLMQNTLPGQVLLQSWLTRNGIDRKLSYVYVQNGWLRRIAHGVYCRTGREPDWVDAVYCLQTQWEKPVRVAGLT
SLALQGYSHYTELGKPQIWLTLPAYIKLPGWFTAFKPSATFVVLYTSGLSVDVMPLTTELRIGDRRLTGSMPELAAYEIA
SGVPAQISFEHADALFQGLNLLSPRKLQALLYASHSVKTNRVMLYLAQRNGHPYFQYLDKSGIETGAGKRQIVPGGWLEP
DYQITVPREFKSEGVEDGSS

Download         Length: 783 bp

>AT231313 NZ_CP126326:69810-70079 [Salmonella enterica subsp. enterica]
ATGTCACAGGTTAACATGAGTTTAAGAATTGATGCCGAACTGAAAGACGCCTTTATGGCTGCAGCAAAAAGTATGGACCG
TAATGGGTCCCAGTTAATCCGGGATTTCATGCGGCAGACTGTTGAACGCCAGCATAATGCCTGGTTCCGTGAACAAATTA
ATGCCGGGCGCCAGCAACTGAAGCGGGGTGAGGTGCTTCCACACGATATGGTGGAAGCATCCGCTGCCGCATGGCGGGAT
AAGATGATGAAAAAGGCTGCCGGTAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References