Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mosAT/AbiEii-AbiEi |
| Location | 4192714..4194412 | Replicon | chromosome |
| Accession | NZ_CP090590 | ||
| Organism | Pectobacterium aroidearum strain QJ315 | ||
Toxin (Protein)
| Gene name | mosT | Uniprot ID | - |
| Locus tag | L0Y23_RS18785 | Protein ID | WP_256542451.1 |
| Coordinates | 4193483..4194412 (+) | Length | 310 a.a. |
Antitoxin (Protein)
| Gene name | mosA | Uniprot ID | - |
| Locus tag | L0Y23_RS18780 | Protein ID | WP_256542450.1 |
| Coordinates | 4192714..4193496 (+) | Length | 261 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| L0Y23_RS18740 (L0Y23_18720) | 4187724..4187984 | + | 261 | WP_256542445.1 | helix-turn-helix transcriptional regulator | - |
| L0Y23_RS18745 (L0Y23_18725) | 4188450..4190300 | + | 1851 | WP_256542446.1 | endonuclease NucS | - |
| L0Y23_RS18750 (L0Y23_18730) | 4190542..4190739 | + | 198 | WP_256542447.1 | hypothetical protein | - |
| L0Y23_RS18755 (L0Y23_18735) | 4190868..4191110 | - | 243 | WP_256542448.1 | helix-turn-helix transcriptional regulator | - |
| L0Y23_RS18760 (L0Y23_18740) | 4191214..4191468 | + | 255 | WP_225181522.1 | helix-turn-helix transcriptional regulator | - |
| L0Y23_RS18765 (L0Y23_18745) | 4191554..4191802 | + | 249 | WP_225181523.1 | helix-turn-helix transcriptional regulator | - |
| L0Y23_RS18770 (L0Y23_18750) | 4191817..4192019 | + | 203 | Protein_3670 | type II toxin-antitoxin system antitoxin CcdA | - |
| L0Y23_RS18775 (L0Y23_18755) | 4192179..4192496 | + | 318 | WP_256542449.1 | hypothetical protein | - |
| L0Y23_RS18780 (L0Y23_18760) | 4192714..4193496 | + | 783 | WP_256542450.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
| L0Y23_RS18785 (L0Y23_18765) | 4193483..4194412 | + | 930 | WP_256542451.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| L0Y23_RS18790 (L0Y23_18770) | 4194796..4195698 | - | 903 | WP_181847077.1 | LysR family transcriptional regulator | - |
| L0Y23_RS18795 (L0Y23_18775) | 4195827..4196090 | + | 264 | WP_012773200.1 | DUF2798 domain-containing protein | - |
| L0Y23_RS18800 (L0Y23_18780) | 4196256..4196639 | - | 384 | Protein_3676 | MBL fold metallo-hydrolase | - |
| L0Y23_RS18805 (L0Y23_18785) | 4196612..4197322 | - | 711 | WP_256543452.1 | thiamine pyrophosphate-binding protein | - |
| L0Y23_RS18810 (L0Y23_18790) | 4197601..4198533 | - | 933 | WP_256542452.1 | phosphoenolpyruvate mutase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 310 a.a. Molecular weight: 35068.40 Da Isoelectric Point: 5.9092
>T231313 WP_256542451.1 NZ_CP090590:4193483-4194412 [Pectobacterium aroidearum]
MDHRDIYARQVKLLMTALPYVAKEPCFALKGGTAINLFVQDFPRLSVDIDLVYQTFIDRDTDLIAIDDALMRITESLNGR
QGLTAIQQENKADEKRIIVNTADAQIKIEVSPVWRGLLLPPAEMPVCEQVEMEYGFTTMSVVSLADLYGGKICAALDRQH
PRDLFDVLNMLEKPCLTREIFDGFLCYLAGHPRPIAELLAPNWDTSRIATLYAQEFSGMTQQETSLESLLSVATLLPQAL
KSHFTAQDRQFLLSYKQNNPDWSLYRYPDIQHLPAIRWKQRNLSALHAKNPAKFSAAVGKLEKVLEQHF
MDHRDIYARQVKLLMTALPYVAKEPCFALKGGTAINLFVQDFPRLSVDIDLVYQTFIDRDTDLIAIDDALMRITESLNGR
QGLTAIQQENKADEKRIIVNTADAQIKIEVSPVWRGLLLPPAEMPVCEQVEMEYGFTTMSVVSLADLYGGKICAALDRQH
PRDLFDVLNMLEKPCLTREIFDGFLCYLAGHPRPIAELLAPNWDTSRIATLYAQEFSGMTQQETSLESLLSVATLLPQAL
KSHFTAQDRQFLLSYKQNNPDWSLYRYPDIQHLPAIRWKQRNLSALHAKNPAKFSAAVGKLEKVLEQHF
Download Length: 930 bp
>T231313 NZ_CP126326:70079-70357 [Salmonella enterica subsp. enterica]
ATGGAGATTTTCTGGACCATGCTGGCCAGTCAGGACAGAAAGCGTATTCGCGAGTACATTGCAGAACAAAATCTGATGGC
TGCTGTTGCACTTGACGAACAGATTAGCGATTCAGCCGGCAGCTTGGCTGAACAACCGTATAAAGGACGTTACGGTCGGG
CTGAAGATACCCGGGAACTGGTCATCCACCCACATTTTGTTCTCGTTTATGAAGTGGATAAACAATGGGGGAAAGTGTAT
ATCCTGCGTGTATTACATACTGCGCAGAAGTGGCCATGA
ATGGAGATTTTCTGGACCATGCTGGCCAGTCAGGACAGAAAGCGTATTCGCGAGTACATTGCAGAACAAAATCTGATGGC
TGCTGTTGCACTTGACGAACAGATTAGCGATTCAGCCGGCAGCTTGGCTGAACAACCGTATAAAGGACGTTACGGTCGGG
CTGAAGATACCCGGGAACTGGTCATCCACCCACATTTTGTTCTCGTTTATGAAGTGGATAAACAATGGGGGAAAGTGTAT
ATCCTGCGTGTATTACATACTGCGCAGAAGTGGCCATGA
Antitoxin
Download Length: 261 a.a. Molecular weight: 29347.66 Da Isoelectric Point: 9.0688
>AT231313 WP_256542450.1 NZ_CP090590:4192714-4193496 [Pectobacterium aroidearum]
MTNYLNWLMQNTLPGQVLLQSWLTRNGIDRKLSYVYVQNGWLRRIAHGVYCRTGREPDWVDAVYCLQTQWEKPVRVAGLT
SLALQGYSHYTELGKPQIWLTLPAYIKLPGWFTAFKPSATFVVLYTSGLSVDVMPLTTELRIGDRRLTGSMPELAAYEIA
SGVPAQISFEHADALFQGLNLLSPRKLQALLYASHSVKTNRVMLYLAQRNGHPYFQYLDKSGIETGAGKRQIVPGGWLEP
DYQITVPREFKSEGVEDGSS
MTNYLNWLMQNTLPGQVLLQSWLTRNGIDRKLSYVYVQNGWLRRIAHGVYCRTGREPDWVDAVYCLQTQWEKPVRVAGLT
SLALQGYSHYTELGKPQIWLTLPAYIKLPGWFTAFKPSATFVVLYTSGLSVDVMPLTTELRIGDRRLTGSMPELAAYEIA
SGVPAQISFEHADALFQGLNLLSPRKLQALLYASHSVKTNRVMLYLAQRNGHPYFQYLDKSGIETGAGKRQIVPGGWLEP
DYQITVPREFKSEGVEDGSS
Download Length: 783 bp
>AT231313 NZ_CP126326:69810-70079 [Salmonella enterica subsp. enterica]
ATGTCACAGGTTAACATGAGTTTAAGAATTGATGCCGAACTGAAAGACGCCTTTATGGCTGCAGCAAAAAGTATGGACCG
TAATGGGTCCCAGTTAATCCGGGATTTCATGCGGCAGACTGTTGAACGCCAGCATAATGCCTGGTTCCGTGAACAAATTA
ATGCCGGGCGCCAGCAACTGAAGCGGGGTGAGGTGCTTCCACACGATATGGTGGAAGCATCCGCTGCCGCATGGCGGGAT
AAGATGATGAAAAAGGCTGCCGGTAAATGA
ATGTCACAGGTTAACATGAGTTTAAGAATTGATGCCGAACTGAAAGACGCCTTTATGGCTGCAGCAAAAAGTATGGACCG
TAATGGGTCCCAGTTAATCCGGGATTTCATGCGGCAGACTGTTGAACGCCAGCATAATGCCTGGTTCCGTGAACAAATTA
ATGCCGGGCGCCAGCAACTGAAGCGGGGTGAGGTGCTTCCACACGATATGGTGGAAGCATCCGCTGCCGCATGGCGGGAT
AAGATGATGAAAAAGGCTGCCGGTAAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|