Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 2875593..2876163 Replicon chromosome
Accession NZ_CP090590
Organism Pectobacterium aroidearum strain QJ315

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag L0Y23_RS12830 Protein ID WP_137740513.1
Coordinates 2875593..2875877 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag L0Y23_RS12835 Protein ID WP_256543426.1
Coordinates 2875924..2876163 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y23_RS12820 (L0Y23_12815) 2873691..2875091 - 1401 WP_256541972.1 HEPN domain-containing protein -
L0Y23_RS12825 (L0Y23_12820) 2875358..2875603 + 246 WP_014914993.1 CopG family ribbon-helix-helix protein -
L0Y23_RS12830 (L0Y23_12825) 2875593..2875877 + 285 WP_137740513.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L0Y23_RS12835 (L0Y23_12830) 2875924..2876163 + 240 WP_256543426.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
L0Y23_RS12840 (L0Y23_12835) 2876221..2876574 + 354 WP_256541973.1 hypothetical protein -
L0Y23_RS12845 2876835..2876960 + 126 WP_256541974.1 hypothetical protein -
L0Y23_RS12850 (L0Y23_12840) 2877578..2878456 + 879 WP_015839856.1 hypothetical protein -
L0Y23_RS12855 (L0Y23_12845) 2878617..2879081 - 465 WP_256541975.1 GyrI-like domain-containing protein -
L0Y23_RS12860 (L0Y23_12850) 2879316..2879645 - 330 WP_181847683.1 DHCW motif cupin fold protein -
L0Y23_RS12865 (L0Y23_12855) 2879711..2880247 - 537 WP_182099558.1 rhodanese family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-79)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11098.90 Da        Isoelectric Point: 9.7867

>T231308 WP_137740513.1 NZ_CP090590:2875593-2875877 [Pectobacterium aroidearum]
MEIKWLRKAAANLEAEYLYIAQDDPQAASQFVDEVQRLTELLPQQPAMGRPGRVPGTRELVLTHYPYIIPYRVKDNMLQI
LRIFHTHRRLPSKW

Download         Length: 285 bp

>T231308 NZ_CP126325:c4635821-4635447 [Salmonella enterica subsp. enterica]
ATGGTCAAAGGGTCTGCGCTTTTTGATACCAATATCCTCATCGACCTGTTTAGCGGTCGAATTGAAGCGAAACATGCGCT
GGAAGCGTATCCGCCACGGAATGCGATTAGCCTTATCACATGGATGGAAGTGATGGTGGGTGCTAAGAAATATCATCAGG
AAAACCGCACGCGCATTGCATTAAGTGCGTTCAATATTATTGGCGTAACACAGGAAATCGCGGAGCGAAGCGTCATTGTC
AGGCAGGAGTATGGCATGAAACTCCCGGATGCGATCATTCTGGCCACTGCACAAGTCCATCGTTGTGAGCTTGTGACGCG
TAATACAAAAGACTTTGCCGATATTCCGGGAGTGATCACGCCGTATCACTTGTAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9185.64 Da        Isoelectric Point: 8.5173

>AT231308 WP_256543426.1 NZ_CP090590:2875924-2876163 [Pectobacterium aroidearum]
MGNVTFRIGDDLKKRSYAALKKLGITPSEAFRLTLEYIAENERLPFKQKLLNDEDVELVEVVRERLRNPKPVRVTLDDL

Download         Length: 240 bp

>AT231308 NZ_CP126325:c4636063-4635821 [Salmonella enterica subsp. enterica]
ATGATGGCTGGGATGGATATGGGCAGAATTTTACTCGATTTATCAGATGATGTGATTAAACGGCTTGACGATCTCAAGGT
GCAACGCAACCTACCTCGTGCAGAACTCTTGCGGGAGGCCGTTGAGCAGTATCTGGAAAGACAGGATCGGGCTGAGACCA
CAATTTCGAAAGCATTGGGGCTCTGGCAAGGCTGTGAGGAAGATGGCGTTGAATACCAACGTAAACTTCGTGAGGAATGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References