Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3777744..3778522 Replicon chromosome
Accession NZ_CP090589
Organism Pectobacterium aroidearum strain QJ316

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag L0Y28_RS16875 Protein ID WP_256542279.1
Coordinates 3777744..3778232 (-) Length 163 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag L0Y28_RS16880 Protein ID WP_205947014.1
Coordinates 3778229..3778522 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y28_RS16840 (L0Y28_16815) 3773004..3773216 - 213 WP_256542275.1 hypothetical protein -
L0Y28_RS16845 (L0Y28_16820) 3773542..3773784 - 243 WP_205947008.1 helix-turn-helix transcriptional regulator -
L0Y28_RS16850 (L0Y28_16825) 3773888..3774142 + 255 WP_039285388.1 helix-turn-helix transcriptional regulator -
L0Y28_RS16855 (L0Y28_16830) 3774228..3774476 + 249 WP_256542276.1 helix-turn-helix transcriptional regulator -
L0Y28_RS16860 (L0Y28_16835) 3774491..3774709 + 219 WP_256542277.1 type II toxin-antitoxin system antitoxin CcdA -
L0Y28_RS16865 (L0Y28_16840) 3774757..3775016 + 260 Protein_3296 type II toxin-antitoxin system toxin CcdB -
L0Y28_RS16870 (L0Y28_16845) 3775397..3777586 - 2190 WP_256542278.1 AAA family ATPase -
L0Y28_RS16875 (L0Y28_16850) 3777744..3778232 - 489 WP_256542279.1 GNAT family N-acetyltransferase Toxin
L0Y28_RS16880 (L0Y28_16855) 3778229..3778522 - 294 WP_205947014.1 DUF1778 domain-containing protein Antitoxin
L0Y28_RS16885 (L0Y28_16860) 3778731..3779687 - 957 WP_256542280.1 AraC family transcriptional regulator -
L0Y28_RS16890 (L0Y28_16865) 3779803..3780990 + 1188 WP_256542281.1 MFS transporter -
L0Y28_RS16895 (L0Y28_16870) 3781117..3781539 - 423 WP_012773533.1 MarR family transcriptional regulator -
L0Y28_RS16900 (L0Y28_16875) 3781700..3782719 + 1020 WP_256542282.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(76-143)

Antitoxin

Vibrio phage ICP1, Orf50

(14-88)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 17421.24 Da        Isoelectric Point: 7.8046

>T231298 WP_256542279.1 NZ_CP090589:c3778232-3777744 [Pectobacterium aroidearum]
MISAPEPLHAEHVLSSFCCGVESMDNWLKQRAMKNQVTGASRTFVSCDGSKVLAYYSLASSAVATNAAPGRFRRNMPDPI
PVVVLGRLAVDKSLHGQGVGRALVRDVGLRVIQVADTIGIRGMLVHALSDEAREFYLRVGFEPSPIDPMLLMVTLGDLVG
SV

Download         Length: 489 bp

>T231298 NZ_CP126325:c1028852-1028325 [Salmonella enterica subsp. enterica]
ATGATGTTTACAGACTGGCATGAGGCCGCGATAGGGAAAACCCACAATCGAATGAATTTTGATTGTGGGGATGCCGATCT
GAACCAATTCCTACAACGCCATGCACTACAAAATCATGAGAAAGGGACAACGAAAACCTATGTTGCGCTTGATAATTCGG
ATGTTACACGTATCCACGGCTTTTACTCAGTCAGTCCTGCATCACTGATATATGCACAGGTTCCCGGCGCAATCAGCAAA
GGATTAGGGAGATATGATGTGCCAGTGTTTCGTCTGGGTCGTTTAGCCGTAGACAAATCTATGCAGGGGCAAGGGCTGGG
AGCACAACTTTTGTTATCTGCCGGAAAGCGTTGCATACAGGCGGCTTTGCAGGTCGGCGGCGTAGCCCTGCTTATTGATG
CCAAAAATAAACAGGTCTGCGACTGGTACAAAGGATTTGGCGCAGTACCATTAAACGATCAACCCCTTTCCTTGTTGCTG
TCGTTTAAAACGCTTTATGCTGCTTTATCTGCATCTGGTAGGTTATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10892.43 Da        Isoelectric Point: 10.1968

>AT231298 WP_205947014.1 NZ_CP090589:c3778522-3778229 [Pectobacterium aroidearum]
MPATNSVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIDQRIIMADPDAYQEFLTRLDQAPSPN
AALRKTMQTSAPWEQKK

Download         Length: 294 bp

>AT231298 NZ_CP126325:c1029139-1028849 [Salmonella enterica subsp. enterica]
ATGAAAACCATGCCTCAGATAGCTATAGAATCTAACGAAAGACTGTCGTTACGTGTATCGACGGATGCCAAAAAGTTGAT
AGTCCGCGCTGCGGCAATCCAGCAAACCAACCTGACGGATTTTGTGGTCAGTAACGTACTACCTGTCGCACAGAAGATTG
TTGATGCCGCCGAACGGGTATATCTGACGGAGCGTGATACTCAAATGATCATGGAAATTTTAGATAACCCGCCAGCGCCG
AATGAAAAGCTTCTTGCCGCTGCTTTCGCCCTGCCGGACATGAAGAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References