Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4877844..4878379 Replicon chromosome
Accession NZ_CP090588
Organism Pectobacterium aroidearum strain AK042

Toxin (Protein)


Gene name relE Uniprot ID A0A7V8Q6Q4
Locus tag L0Y25_RS22150 Protein ID WP_039284929.1
Coordinates 4878092..4878379 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q6DB37
Locus tag L0Y25_RS22145 Protein ID WP_010281712.1
Coordinates 4877844..4878095 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y25_RS22120 (L0Y25_22095) 4873140..4874273 + 1134 WP_256554020.1 alkylhydroperoxidase domain protein -
L0Y25_RS22125 (L0Y25_22100) 4874316..4874939 - 624 WP_256554021.1 LysE family translocator -
L0Y25_RS22130 (L0Y25_22105) 4875120..4875824 + 705 WP_256554022.1 SMI1/KNR4 family protein -
L0Y25_RS22135 (L0Y25_22110) 4875894..4876649 + 756 WP_256554023.1 thiol:disulfide interchange protein DsbG -
L0Y25_RS22140 (L0Y25_22115) 4876684..4877589 - 906 WP_256554024.1 siderophore-interacting protein -
L0Y25_RS22145 (L0Y25_22120) 4877844..4878095 + 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
L0Y25_RS22150 (L0Y25_22125) 4878092..4878379 + 288 WP_039284929.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L0Y25_RS22155 (L0Y25_22130) 4878487..4879839 - 1353 WP_256554025.1 glutathione-disulfide reductase -
L0Y25_RS22160 (L0Y25_22135) 4879968..4880810 - 843 WP_256554026.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
L0Y25_RS22165 (L0Y25_22140) 4881029..4881757 + 729 WP_256554027.1 DUF1266 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11088.18 Da        Isoelectric Point: 10.3527

>T231290 WP_039284929.1 NZ_CP090588:4878092-4878379 [Pectobacterium aroidearum]
MSYSVKFREDALKEWLKLDKTIQQQFAKKLKKCCENPHIPSAKLRGMKDCYKIKLRASGFRLVYEVIDDILIIAVVAVGK
RERSGVYHLASERMR

Download         Length: 288 bp

>T231290 NZ_CP126323:c3987532-3987119 [Salmonella enterica subsp. enterica]
GTGGTCCTGTGGCAATCTGATTTACGCGTCTCATGGCGCGCTCAGTGGATCTCATTGCTCATTCATGGGCTGGTTGCCGC
GGTGATTTTATTGATGCCCTGGCCGCTGAGTTATACCCCGTTATGGATGATACTACTGTCGCTGGTCGTGTTTGACTGTG
TACGTAGCCAGCGCAGGATTAATACCTGCCAGGGAGAGATCAAGCTACTCATGGACGGGCGCTTACGCTGGCAGGGGCAG
GACTGGACGCTCTTGCGTCCGCCCTGGTTACTGAAGAGCGGGATGGTGTTGCGTTTACGCGCAGAGTCTGGACGTCATCA
GCATTTATGGCTGGCGGCGGATAGCATGGAAGAAGCGGAATGGCGTGAGTTGCGTCGGATACTGTTACAGCAGCCGATAT
CAGGCCAACACTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9117.47 Da        Isoelectric Point: 4.0637

>AT231290 WP_010281712.1 NZ_CP090588:4877844-4878095 [Pectobacterium aroidearum]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Download         Length: 252 bp

>AT231290 NZ_CP126323:c3987779-3987513 [Salmonella enterica subsp. enterica]
ATGGATATTCACAATAAAGCACGTATTCACTGGGCATGTCGTCGCGGTATGCGCGAACTTGATATTTCCATCATGCCGTT
TTTTGAACATGAGTACGATAGTTTAAGTGATGAAGAAAAGCGTATTTTTGTCCGTTTGTTGCAGAGTGACGACCCGGATT
TATTTAACTGGTTAATGAATCACGGTAAACCGGCTGACGCTGAACTGGAACAGATGGTCCGACTCATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7V8Q6Q4

Antitoxin

Source ID Structure
AlphaFold DB A0A0M2EZP0

References