Detailed information of TA system TA231289

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): stbDE/ParE-DnaT
• Location: 4581568..4582099
• Replicon: chromosome
• Accession: NZ_CP090588
• Organism: Pectobacterium aroidearum strain AK042

Toxin (Protein)

• Gene name: stbE
• Uniprot ID: -
• Locus tag: L0Y25_RS20760
• Protein ID: WP_181845773.1
• Coordinates: 4581568..4581855 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: stbD
• Uniprot ID: -
• Locus tag: L0Y25_RS20765
• Protein ID: WP_180778477.1
• Coordinates: 4581845..4582099 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L0Y25_RS20740 (L0Y25_20715)	4577030..4578421	+	1392	WP_256553944.1	outer membrane channel protein TolC	-
L0Y25_RS20745 (L0Y25_20720)	4578688..4579362	+	675	WP_012773030.1	DUF1190 family protein	-
L0Y25_RS20750 (L0Y25_20725)	4579374..4580534	+	1161	WP_180778474.1	glutathionylspermidine synthase family protein	-
L0Y25_RS20755 (L0Y25_20730)	4580604..4581389	-	786	WP_256553945.1	4,5-DOPA dioxygenase extradiol	-
L0Y25_RS20760 (L0Y25_20735)	4581568..4581855	-	288	WP_181845773.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
L0Y25_RS20765 (L0Y25_20740)	4581845..4582099	-	255	WP_180778477.1	plasmid stabilization protein	Antitoxin
L0Y25_RS20770 (L0Y25_20745)	4582557..4583750	+	1194	WP_181848129.1	IS4 family transposase	-
L0Y25_RS20780 (L0Y25_20755)	4584201..4585088	-	888	WP_194431461.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	4582557..4583750	1193

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-87)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11072.06 Da
• Isoelectric Point: 10.7694

>T231289 WP_181845773.1 NZ_CP090588:c4581855-4581568 [Pectobacterium aroidearum]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMIMGVGK
REGSQVYFDTKGRSA

Nucleotide

• Length: 288 bp

>T231289 NZ_CP126323:c3976611-3976213 [Salmonella enterica subsp. enterica]
ATGCTGAAATTCATGCTTGATACCAATACCTGTATTTTCACCATCAAAAATAAGCCCGAACACATCAGAGAACGCTTCAA
CCTCAATACATCCCGAATGTGTATCAGCTCCATCACCTTAATGGAGCTGATTTACGGTGCTGAAAAAAGCCTGGCGCCGG
AGCGTAATCTTGCCGTCGTGGAGGGATTTATCTCCCGCCTTGAGGTTCTGGATTACGATACACAGGCAGCGATACATACC
GGTCAAATCCGTGCCGAATTGGCCCGCAAGGGAACACCTGTCGGGCCTTATGACCAGATGATTGCTGGCCATGCCGGTAG
CCGCGGACTGGTCGTCGTCACAAACAATCTCCGCGAATTTGAACGCATTCCGGGTATCCGAATCGAAGACTGGTGCTAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9240.44 Da
• Isoelectric Point: 3.7947

>AT231289 WP_180778477.1 NZ_CP090588:c4582099-4581845 [Pectobacterium aroidearum]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAMFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Nucleotide

• Length: 255 bp

>AT231289 NZ_CP126323:c3976856-3976611 [Salmonella enterica subsp. enterica]
ATCCAGAAAGGAGGCAGTTATGCACACAACACTTTTTTTAGTAACCGGACCCAGGCAGTCAGATTGCCTAAATCGATATC
CTTTCCGGAGGATGTGAAACATGTCGAAATCATTGCGGTTGGTAGAAGCAGAATCATTACTCCAGTCGGAGAATCCTGGG
ACAGCTGGTTCGATGGCGAAGGCGCCAGTACTGATTTTATGAGTACCAGAGAACAACCCGCAGTACAGGAACGGGAAGGA
TTTTGA