Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 4359214..4359992 Replicon chromosome
Accession NZ_CP090588
Organism Pectobacterium aroidearum strain AK042

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag L0Y25_RS19770 Protein ID WP_256553870.1
Coordinates 4359214..4359702 (-) Length 163 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag L0Y25_RS19775 Protein ID WP_256553871.1
Coordinates 4359699..4359992 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y25_RS19730 (L0Y25_19705) 4354515..4354706 - 192 WP_116165064.1 YlcI/YnfO family protein -
L0Y25_RS19735 (L0Y25_19710) 4354892..4355233 + 342 WP_256553865.1 hypothetical protein -
L0Y25_RS19740 (L0Y25_19715) 4355687..4356037 - 351 WP_256553866.1 hypothetical protein -
L0Y25_RS19745 (L0Y25_19720) 4356135..4356878 + 744 WP_256553867.1 MobC family replication-relaxation protein -
L0Y25_RS19750 (L0Y25_19725) 4356937..4357155 + 219 WP_015855076.1 type II toxin-antitoxin system antitoxin CcdA -
L0Y25_RS19755 (L0Y25_19730) 4357158..4357325 + 168 Protein_3864 CcdB family protein -
L0Y25_RS19760 (L0Y25_19735) 4357632..4358624 + 993 WP_256553868.1 GAF domain-containing protein -
L0Y25_RS19765 (L0Y25_19740) 4358753..4358977 + 225 WP_256553869.1 hypothetical protein -
L0Y25_RS19770 (L0Y25_19745) 4359214..4359702 - 489 WP_256553870.1 GNAT family N-acetyltransferase Toxin
L0Y25_RS19775 (L0Y25_19750) 4359699..4359992 - 294 WP_256553871.1 DUF1778 domain-containing protein Antitoxin
L0Y25_RS19780 (L0Y25_19755) 4360333..4360575 - 243 WP_226294582.1 helix-turn-helix transcriptional regulator -
L0Y25_RS19785 (L0Y25_19760) 4360696..4360956 + 261 WP_181847074.1 helix-turn-helix transcriptional regulator -
L0Y25_RS19790 (L0Y25_19765) 4361336..4362199 + 864 WP_181847075.1 hypothetical protein -
L0Y25_RS19795 (L0Y25_19770) 4362183..4362605 + 423 WP_181847076.1 hypothetical protein -
L0Y25_RS19800 (L0Y25_19775) 4362987..4363247 + 261 WP_094433671.1 helix-turn-helix transcriptional regulator -
L0Y25_RS19805 (L0Y25_19780) 4363326..4364228 - 903 WP_181847077.1 LysR family transcriptional regulator -
L0Y25_RS19810 (L0Y25_19785) 4364357..4364620 + 264 WP_012773200.1 DUF2798 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 4272109..4360250 88141


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(82-143)

Antitoxin

Vibrio phage ICP1, Orf50

(5-95)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 17411.22 Da        Isoelectric Point: 7.8046

>T231286 WP_256553870.1 NZ_CP090588:c4359702-4359214 [Pectobacterium aroidearum]
MISAPEPVHAEHVLSSFCCGVESMDNWLKQRAIKNQVSGASRTFVSCGDSKVLAYYSLASSAVATNAAPGRFRRNMPDPI
PVVVLGRLAVDKSLHGQGVGRALVRDAGLRVIQVADTIGIRGILVHALSDEAREFYLRVGFEPSPIDPMMLMMTLGDLMG
SV

Download         Length: 489 bp

>T231286 NZ_CP126323:3379304-3379522 [Salmonella enterica subsp. enterica]
ATGTCTGATAAACCATTAACTAAAACTGATTATTTGATGCGTTTACGGCGCTGTCAGACAATTGACACTCTGGAGCGCGT
CATTGAGAAAAATAAATATGAATTGTCCGACAATGAGCTGGCTGTATTTTACTCAGCTGCGGATCACCGTCTTGCAGAAT
TGACGATGAACAAACTCTACGACAAGATCCCCTCTTCAGTATGGAAATTCATTCGTTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10969.65 Da        Isoelectric Point: 10.4623

>AT231286 WP_256553871.1 NZ_CP090588:c4359992-4359699 [Pectobacterium aroidearum]
MPVRNSVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPDAYQEFLARLDQAPAPN
AALRKTMQTLAPWEQKK

Download         Length: 294 bp

>AT231286 NZ_CP126323:3378902-3379276 [Salmonella enterica subsp. enterica]
ATGGACGAATACTCACCCAAAAGACATGATATAGCACAGCTTAAATTTCTTTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAACCATGGCTGGGTTAATGACCCGACCTCAGCAGTCAACCTGCAGCTCAATGAGCTGATAGAGC
ATATTGCAACTTTCGCGCTTAATTATAAAATTAAGTACAATGAAGACAATAAATTGATTGCGCAGATAGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTATGGTATTAATACGCAGGATTTGCAAAAATGGCGTAAATCGGGCAACCGCCT
GTTCCGTTGTTTCGTCAACGCCACCAAGGCCAATCCTGTTAGTTTGTCTTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References