Detailed information of TA system TA231284

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ccdAB/CcdA(antitoxin)
• Location: 3914839..3915365
• Replicon: chromosome
• Accession: NZ_CP090588
• Organism: Pectobacterium aroidearum strain AK042

Toxin (Protein)

• Gene name: ccdB
• Uniprot ID: -
• Locus tag: L0Y25_RS17750
• Protein ID: WP_256553763.1
• Coordinates: 3915060..3915365 (+)
• Length: 102 a.a.

Antitoxin (Protein)

• Gene name: ccdA
• Uniprot ID: E0SK21
• Locus tag: L0Y25_RS17745
• Protein ID: WP_012773205.1
• Coordinates: 3914839..3915057 (+)
• Length: 73 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	3909429..3925622	16193
	-	flank	IS/Tn	-	-	3911822..3913132	1310

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin CcdB (2-100)

Antitoxin

• Post-segregation antitoxin CcdA (2-72)

Sequences

Toxin

Protein

• Length: 102 a.a.
• Molecular weight: 11785.63 Da
• Isoelectric Point: 4.8564

>T231284 WP_256553763.1 NZ_CP090588:3915060-3915365 [Pectobacterium aroidearum]
MQFIVYQYKRASHYKMFVDVQSDIVETPKRRMVIPLIETHHLSEKVNKTLFPQIHIEGEDYRLMTTELSSVPVEVIGEAI
VDLGDYADEIKDAINLMFWGI

Nucleotide

• Length: 306 bp

>T231284 NZ_CP126323:807210-807497 [Salmonella enterica subsp. enterica]
ATGCCGATGGAGTTTGAATGGGATGCGAACAAGGCTAAAAGCAACCTGAGGAAGCACGGTGTCCGCTTTGAGGATGCGGT
ACTGGTGTTTGACGATCCCCGACACCTGTCACGTCAGGAGCGTTATGAGAATGGAGAATATCGTTGGCAGACCCTCGGCC
TTGTTCATGGCATTGTGGTCATTCTGGTTGCTCATAGCGTTCGGTTCGAAAGTGGTTTTGAAGTTATCCGTATCATCAGC
GCTCGCAAGGCAGACAGAAAAGAGAGGAATCGTTATGAGCATGGTTAA

Antitoxin

Protein

• Length: 73 a.a.
• Molecular weight: 8201.16 Da
• Isoelectric Point: 7.2038

>AT231284 WP_012773205.1 NZ_CP090588:3914839-3915057 [Pectobacterium aroidearum]
MKHRVSVTVDKDNYQVLSAAGVNISGLVNDAIGKEARRIKAEEWKKENREGMEEVARFIAQHGSFADENRNW

Nucleotide

• Length: 219 bp

>AT231284 NZ_CP126323:807484-807786 [Salmonella enterica subsp. enterica]
ATGAGCATGGTTAAACATAAACGCGGCAATGCATCCGCGCTGAGTGCTCAGCATGAGGCTGAACTGAAGGCGCTGGCGAA
AAAATCAGATGATGAGATTGATTACAGCGACATTCCCGCTTCGGAGGATGGGCAGTGGTCTGAAGCAGTGCGTGGTAAGT
TTTTTCGCCCGTTAAAAACTCAGGCCTCGGTGCGTATTGACGCCGATGTGATGGAGTGGCTGAAACGGCCAGGAAAAGGC
TACCAGACGCGGCTCAATGCCATTCTGCGCGAGGCGATGCTGCGCGAGCAAAATAAGAAATAG

Structures

Antitoxin

• AlphaFold DB: E0SK21