Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | ccdAB/CcdA(antitoxin) |
Location | 3914839..3915365 | Replicon | chromosome |
Accession | NZ_CP090588 | ||
Organism | Pectobacterium aroidearum strain AK042 |
Toxin (Protein)
Gene name | ccdB | Uniprot ID | - |
Locus tag | L0Y25_RS17750 | Protein ID | WP_256553763.1 |
Coordinates | 3915060..3915365 (+) | Length | 102 a.a. |
Antitoxin (Protein)
Gene name | ccdA | Uniprot ID | E0SK21 |
Locus tag | L0Y25_RS17745 | Protein ID | WP_012773205.1 |
Coordinates | 3914839..3915057 (+) | Length | 73 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
L0Y25_RS17725 (L0Y25_17700) | 3910972..3911166 | - | 195 | WP_012773549.1 | YlcI/YnfO family protein | - |
L0Y25_RS17730 (L0Y25_17705) | 3911352..3911693 | + | 342 | WP_256553761.1 | hypothetical protein | - |
L0Y25_RS17735 (L0Y25_17710) | 3911822..3913132 | + | 1311 | WP_180776519.1 | IS4 family transposase | - |
L0Y25_RS17740 (L0Y25_17715) | 3914037..3914780 | + | 744 | WP_256553762.1 | MobC family replication-relaxation protein | - |
L0Y25_RS17745 (L0Y25_17720) | 3914839..3915057 | + | 219 | WP_012773205.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin |
L0Y25_RS17750 (L0Y25_17725) | 3915060..3915365 | + | 306 | WP_256553763.1 | type II toxin-antitoxin system toxin CcdB | Toxin |
L0Y25_RS17755 (L0Y25_17730) | 3916065..3918521 | + | 2457 | WP_112092901.1 | N-6 DNA methylase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Integrative and Conjugative Element | - | - | 3909429..3925622 | 16193 | |
- | flank | IS/Tn | - | - | 3911822..3913132 | 1310 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 102 a.a. Molecular weight: 11785.63 Da Isoelectric Point: 4.8564
>T231284 WP_256553763.1 NZ_CP090588:3915060-3915365 [Pectobacterium aroidearum]
MQFIVYQYKRASHYKMFVDVQSDIVETPKRRMVIPLIETHHLSEKVNKTLFPQIHIEGEDYRLMTTELSSVPVEVIGEAI
VDLGDYADEIKDAINLMFWGI
MQFIVYQYKRASHYKMFVDVQSDIVETPKRRMVIPLIETHHLSEKVNKTLFPQIHIEGEDYRLMTTELSSVPVEVIGEAI
VDLGDYADEIKDAINLMFWGI
Download Length: 306 bp
>T231284 NZ_CP126323:807210-807497 [Salmonella enterica subsp. enterica]
ATGCCGATGGAGTTTGAATGGGATGCGAACAAGGCTAAAAGCAACCTGAGGAAGCACGGTGTCCGCTTTGAGGATGCGGT
ACTGGTGTTTGACGATCCCCGACACCTGTCACGTCAGGAGCGTTATGAGAATGGAGAATATCGTTGGCAGACCCTCGGCC
TTGTTCATGGCATTGTGGTCATTCTGGTTGCTCATAGCGTTCGGTTCGAAAGTGGTTTTGAAGTTATCCGTATCATCAGC
GCTCGCAAGGCAGACAGAAAAGAGAGGAATCGTTATGAGCATGGTTAA
ATGCCGATGGAGTTTGAATGGGATGCGAACAAGGCTAAAAGCAACCTGAGGAAGCACGGTGTCCGCTTTGAGGATGCGGT
ACTGGTGTTTGACGATCCCCGACACCTGTCACGTCAGGAGCGTTATGAGAATGGAGAATATCGTTGGCAGACCCTCGGCC
TTGTTCATGGCATTGTGGTCATTCTGGTTGCTCATAGCGTTCGGTTCGAAAGTGGTTTTGAAGTTATCCGTATCATCAGC
GCTCGCAAGGCAGACAGAAAAGAGAGGAATCGTTATGAGCATGGTTAA
Antitoxin
Download Length: 73 a.a. Molecular weight: 8201.16 Da Isoelectric Point: 7.2038
>AT231284 WP_012773205.1 NZ_CP090588:3914839-3915057 [Pectobacterium aroidearum]
MKHRVSVTVDKDNYQVLSAAGVNISGLVNDAIGKEARRIKAEEWKKENREGMEEVARFIAQHGSFADENRNW
MKHRVSVTVDKDNYQVLSAAGVNISGLVNDAIGKEARRIKAEEWKKENREGMEEVARFIAQHGSFADENRNW
Download Length: 219 bp
>AT231284 NZ_CP126323:807484-807786 [Salmonella enterica subsp. enterica]
ATGAGCATGGTTAAACATAAACGCGGCAATGCATCCGCGCTGAGTGCTCAGCATGAGGCTGAACTGAAGGCGCTGGCGAA
AAAATCAGATGATGAGATTGATTACAGCGACATTCCCGCTTCGGAGGATGGGCAGTGGTCTGAAGCAGTGCGTGGTAAGT
TTTTTCGCCCGTTAAAAACTCAGGCCTCGGTGCGTATTGACGCCGATGTGATGGAGTGGCTGAAACGGCCAGGAAAAGGC
TACCAGACGCGGCTCAATGCCATTCTGCGCGAGGCGATGCTGCGCGAGCAAAATAAGAAATAG
ATGAGCATGGTTAAACATAAACGCGGCAATGCATCCGCGCTGAGTGCTCAGCATGAGGCTGAACTGAAGGCGCTGGCGAA
AAAATCAGATGATGAGATTGATTACAGCGACATTCCCGCTTCGGAGGATGGGCAGTGGTCTGAAGCAGTGCGTGGTAAGT
TTTTTCGCCCGTTAAAAACTCAGGCCTCGGTGCGTATTGACGCCGATGTGATGGAGTGGCTGAAACGGCCAGGAAAAGGC
TACCAGACGCGGCTCAATGCCATTCTGCGCGAGGCGATGCTGCGCGAGCAAAATAAGAAATAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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