Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 3167379..3168103 Replicon chromosome
Accession NZ_CP090588
Organism Pectobacterium aroidearum strain AK042

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag L0Y25_RS14485 Protein ID WP_256553521.1
Coordinates 3167379..3167699 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag L0Y25_RS14490 Protein ID WP_249653329.1
Coordinates 3167768..3168103 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y25_RS14455 (L0Y25_14440) 3162680..3164095 + 1416 WP_181848683.1 diguanylate cyclase -
L0Y25_RS14460 (L0Y25_14445) 3164367..3164585 + 219 WP_015840821.1 KTSC domain-containing protein -
L0Y25_RS14465 (L0Y25_14450) 3164806..3165162 + 357 WP_182100027.1 hypothetical protein -
L0Y25_RS14470 (L0Y25_14455) 3165700..3166104 - 405 WP_256553519.1 tRNA(fMet)-specific endonuclease VapC -
L0Y25_RS14475 (L0Y25_14460) 3166104..3166334 - 231 WP_012765080.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
L0Y25_RS14480 (L0Y25_14465) 3166428..3167261 - 834 WP_256553520.1 DUF4942 domain-containing protein -
L0Y25_RS14485 (L0Y25_14470) 3167379..3167699 - 321 WP_256553521.1 TA system toxin CbtA family protein Toxin
L0Y25_RS14490 (L0Y25_14475) 3167768..3168103 - 336 WP_249653329.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
L0Y25_RS14495 (L0Y25_14480) 3168143..3168616 - 474 WP_249653330.1 DNA repair protein RadC -
L0Y25_RS14500 (L0Y25_14485) 3168739..3169089 - 351 WP_256553522.1 hypothetical protein -
L0Y25_RS14505 (L0Y25_14490) 3169147..3169980 - 834 WP_256553523.1 hypothetical protein -
L0Y25_RS14510 (L0Y25_14495) 3170127..3170285 - 159 WP_155242703.1 hypothetical protein -
L0Y25_RS14515 (L0Y25_14500) 3170469..3171356 - 888 WP_256553524.1 50S ribosome-binding GTPase -
L0Y25_RS14520 (L0Y25_14505) 3171451..3172119 - 669 WP_256553525.1 hypothetical protein -
L0Y25_RS14525 (L0Y25_14510) 3172493..3173080 + 588 WP_256553526.1 inovirus-type Gp2 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12077.81 Da        Isoelectric Point: 4.7768

>T231281 WP_256553521.1 NZ_CP090588:c3167699-3167379 [Pectobacterium aroidearum]
MQTSPAIPPREDNPCPSPIAVWQQLLTYLLEKHYGLTLNDTPFCEENVIQEHIDAGITLVNAVNFLVEKYELVRIDRNGF
NWQEQSPFLTAVDILRARRATGLLKA

Download         Length: 321 bp

>T231281 NZ_CP126323:614465-614956 [Salmonella enterica subsp. enterica]
ATGATCTCCACCCCTGAGCCGCTTCATGCCGGACATATTCTTACTCCGTTTTGCTGCGGTGTGGATTCTATAGATAACTG
GCTGAAACAGCGGGCGATGAAAAATCAGACCACTGGCGCGTCCCGTACCTTTGTGTGTTGTGGCAGCGATTCGAACGTAC
TGGCCTATTACTCGCTGGCGTCCAGCGCGGTCACGACGAATACCTCCCCCGGTCGCTTTCGTCGCAATATGCCTGACCCG
ATTCCGGTTGTGGTATTGGGGCGTCTGGCGGTGGATAAATCGCTTCATGGGCAGGGCGTCGCTCGGGCGCTGGTACGCGA
CGCAGGGCTGCGGGTTATTCAGGTGGCGGAGACTATCGGCATTCGTGGGATGCTGGTTCACGCCCTGTCGGATGAAGCGC
GGGAATTTTATCAGCGGGTGGGGTTTGTACCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGGGGGATTTGGTG
GAGAGTGTTTAA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12529.41 Da        Isoelectric Point: 7.1655

>AT231281 WP_249653329.1 NZ_CP090588:c3168103-3167768 [Pectobacterium aroidearum]
MPSSDTPEWGLKCAITRRFGARLVQEGHRLHYLADRASIVGTFSKTEAQSLERCFPELIKLLEQKLRMGELNPRQQKCVT
LHCNEWICEADTLGSVGYVYIVIYPSSAAAE

Download         Length: 336 bp

>AT231281 NZ_CP126323:614175-614468 [Salmonella enterica subsp. enterica]
ATGCCAGCCGCAAACAGTATGGCGATGAAACGCGAAACCCTGAACCTGCGTATCAAACCCGCCGAGCGCGATCTTATTGA
TCGAGCGGCGAAAGCCAGAGGGAAAAACCGCACTGACTTTGTGCTGGAAGCTGCCCGTGCTGCCGCCGAGGAAGCGCTGA
TCGAACAACGCATCATTATGGCCGATCCAGAGGCTTATCAGGAGTTTCTCGTTCGTTTGGATCAAACACCTTCACCTAAT
GCCGCACTGCGTAAAACCATGCAGACCCCTGCGCCGTGGGAGCAGGAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References