Detailed information of TA system TA231275

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): stbDE/ParE-DnaT
• Location: 4581401..4581932
• Replicon: chromosome
• Accession: NZ_CP090587
• Organism: Pectobacterium aroidearum strain AK049

Toxin (Protein)

• Gene name: stbE
• Uniprot ID: -
• Locus tag: L0Y26_RS20760
• Protein ID: WP_181845773.1
• Coordinates: 4581401..4581688 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: stbD
• Uniprot ID: -
• Locus tag: L0Y26_RS20765
• Protein ID: WP_180778477.1
• Coordinates: 4581678..4581932 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L0Y26_RS20740 (L0Y26_20710)	4576863..4578254	+	1392	WP_256553944.1	outer membrane channel protein TolC	-
L0Y26_RS20745 (L0Y26_20715)	4578521..4579195	+	675	WP_012773030.1	DUF1190 family protein	-
L0Y26_RS20750 (L0Y26_20720)	4579207..4580367	+	1161	WP_180778474.1	glutathionylspermidine synthase family protein	-
L0Y26_RS20755 (L0Y26_20725)	4580437..4581222	-	786	WP_256553945.1	4,5-DOPA dioxygenase extradiol	-
L0Y26_RS20760 (L0Y26_20730)	4581401..4581688	-	288	WP_181845773.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
L0Y26_RS20765 (L0Y26_20735)	4581678..4581932	-	255	WP_180778477.1	plasmid stabilization protein	Antitoxin
L0Y26_RS20770 (L0Y26_20740)	4582390..4583583	+	1194	WP_181848129.1	IS4 family transposase	-
L0Y26_RS20780 (L0Y26_20750)	4584034..4584921	-	888	WP_194431461.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	4582390..4583583	1193

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-87)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11072.06 Da
• Isoelectric Point: 10.7694

>T231275 WP_181845773.1 NZ_CP090587:c4581688-4581401 [Pectobacterium aroidearum]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMIMGVGK
REGSQVYFDTKGRSA

Nucleotide

• Length: 288 bp

>T231275 NZ_CP126307:c4689271-4688846 [Bosea vestrisii]
GTGAGAATCCTGCTCGACACTAACGTCATTTCCGAACCGCAGAAACCGCAGCCATCTGCGGCAGTCGAGCGTTTCATTCG
GGACACGCCGGAAGAAGGCCTCTTCCTCAGCATCATCACGATAGCGGAACTCTACCGCAGCGTAGCGTTTATGACGGAAG
GTCGCCGACGCATCCGCTTGAGCGAATGGGTCACGGCCGAGCTTCCGGAGCGTTTCGGCGACCGGCTCCTGCCCATCACA
ACATCAATTGCCGCGCTCTGGGGCGACGTGATGGCGCAATCTCGTCGCGACGGGCTGAACATGTCCATCATGGACGGCTT
TCTCGCTGCAACAGCAGCGGCGCACGGCTTGGCCATCGCCACGCGCAACGTGCGCCATTTTACAGGCCTTGGCCTGACCG
TGATTGATCCTTGGGGCGAGAGCTAG

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9240.44 Da
• Isoelectric Point: 3.7947

>AT231275 WP_180778477.1 NZ_CP090587:c4581932-4581678 [Pectobacterium aroidearum]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAMFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Nucleotide

• Length: 255 bp

>AT231275 NZ_CP126307:c4689531-4689268 [Bosea vestrisii]
ATGACATCGGCATCGAAGACGAGCTGGAGCGTCGCCAACGCGAAGGCGCGCTTCTCCGAACTCATCGACAAGGCGAAATC
CGAAGGCCCACAGACTGTGACGCGCAATGGCAAGCCGACGGTGATGCTGGTGTCGGTGGAAGAGTGGGAGAAGAGGACGG
CGCCGAAAGGAACCTTGCTCGAATTTCTCCAGAATTCGCCACTTCGTGGGGCTGACCTCGATCTCAGGCGCCTCGCCGAC
CAGCCGCGTGACATCGAGCTGTGA