Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 4359048..4359826 Replicon chromosome
Accession NZ_CP090587
Organism Pectobacterium aroidearum strain AK049

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag L0Y26_RS19770 Protein ID WP_256553870.1
Coordinates 4359048..4359536 (-) Length 163 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag L0Y26_RS19775 Protein ID WP_256553871.1
Coordinates 4359533..4359826 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y26_RS19730 (L0Y26_19700) 4354349..4354540 - 192 WP_116165064.1 YlcI/YnfO family protein -
L0Y26_RS19735 (L0Y26_19705) 4354726..4355067 + 342 WP_256553865.1 hypothetical protein -
L0Y26_RS19740 (L0Y26_19710) 4355521..4355871 - 351 WP_256553866.1 hypothetical protein -
L0Y26_RS19745 (L0Y26_19715) 4355969..4356712 + 744 WP_256553867.1 MobC family replication-relaxation protein -
L0Y26_RS19750 (L0Y26_19720) 4356771..4356989 + 219 WP_015855076.1 type II toxin-antitoxin system antitoxin CcdA -
L0Y26_RS19755 (L0Y26_19725) 4356992..4357159 + 168 Protein_3864 CcdB family protein -
L0Y26_RS19760 (L0Y26_19730) 4357466..4358458 + 993 WP_256553868.1 GAF domain-containing protein -
L0Y26_RS19765 (L0Y26_19735) 4358587..4358811 + 225 WP_256553869.1 hypothetical protein -
L0Y26_RS19770 (L0Y26_19740) 4359048..4359536 - 489 WP_256553870.1 GNAT family N-acetyltransferase Toxin
L0Y26_RS19775 (L0Y26_19745) 4359533..4359826 - 294 WP_256553871.1 DUF1778 domain-containing protein Antitoxin
L0Y26_RS19780 (L0Y26_19750) 4360167..4360409 - 243 WP_226294582.1 helix-turn-helix transcriptional regulator -
L0Y26_RS19785 (L0Y26_19755) 4360530..4360790 + 261 WP_181847074.1 helix-turn-helix transcriptional regulator -
L0Y26_RS19790 (L0Y26_19760) 4361170..4362033 + 864 WP_181847075.1 hypothetical protein -
L0Y26_RS19795 (L0Y26_19765) 4362017..4362439 + 423 WP_181847076.1 hypothetical protein -
L0Y26_RS19800 (L0Y26_19770) 4362821..4363081 + 261 WP_094433671.1 helix-turn-helix transcriptional regulator -
L0Y26_RS19805 (L0Y26_19775) 4363160..4364062 - 903 WP_181847077.1 LysR family transcriptional regulator -
L0Y26_RS19810 (L0Y26_19780) 4364191..4364454 + 264 WP_012773200.1 DUF2798 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 4271943..4360084 88141


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(82-143)

Antitoxin

Vibrio phage ICP1, Orf50

(5-95)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 17411.22 Da        Isoelectric Point: 7.8046

>T231272 WP_256553870.1 NZ_CP090587:c4359536-4359048 [Pectobacterium aroidearum]
MISAPEPVHAEHVLSSFCCGVESMDNWLKQRAIKNQVSGASRTFVSCGDSKVLAYYSLASSAVATNAAPGRFRRNMPDPI
PVVVLGRLAVDKSLHGQGVGRALVRDAGLRVIQVADTIGIRGILVHALSDEAREFYLRVGFEPSPIDPMMLMMTLGDLMG
SV

Download         Length: 489 bp

>T231272 NZ_CP126307:3165031-3165315 [Bosea vestrisii]
ATGAAGCTCGTCTGGACCGCAAGAGCAAAGGCTGACCTTCGCGCTATCGCTCTCTATGTCGCCGACTTCAGTCCAACGGC
AGCGCTCGCCCTCGTCCGCCGACTCCGCTCAGCCGCCGCCCAGTTGGTCGACTACCCGCATAGTGGCCGAGCCGGACGGG
TAGAAGAGACGCGTGAACTCGTGGTAGCCGGCACCAGCTACATCCTCCCCTATCGCGTCCGAGATGGACGCGTCGAAATC
CTCGCTGTCCTGCACGCCTCGCGGCAATGGCCGGACCAGCTCTGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10969.65 Da        Isoelectric Point: 10.4623

>AT231272 WP_256553871.1 NZ_CP090587:c4359826-4359533 [Pectobacterium aroidearum]
MPVRNSVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPDAYQEFLARLDQAPAPN
AALRKTMQTLAPWEQKK

Download         Length: 294 bp

>AT231272 NZ_CP126307:3164783-3165034 [Bosea vestrisii]
ATGACGGCAGCTTTCACAATCCGCCTCGACGACGAGACCCTCGCCAAGCTCGATGCGTTGGCAATTGACACTGACCGGTC
GCGCAACTGGCTCGCCGCCAAGGCGATCGAGAACTATATCGAACTCAATGCTTGGCAGATCGCGCGGATCAGGGAAGGCA
TCTCCCAAGCCGATCGCGGTGAATTCGCCACGGAGGCAGAGCTCGATGCCATCGAGACGGAACTGCAGGCGCGCATCGAT
TCGACCAGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References