Detailed information of TA system TA231271

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 4118107..4118767
• Replicon: chromosome
• Accession: NZ_CP090587
• Organism: Pectobacterium aroidearum strain AK049

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: L0Y26_RS18595
• Protein ID: WP_043881709.1
• Coordinates: 4118107..4118481 (-)
• Length: 125 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: C6D8Y5
• Locus tag: L0Y26_RS18600
• Protein ID: WP_012773340.1
• Coordinates: 4118501..4118767 (-)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L0Y26_RS18570 (L0Y26_18540)	4113484..4114383	-	900	WP_012773347.1	site-specific tyrosine recombinase XerD	-
L0Y26_RS18575 (L0Y26_18545)	4114695..4116023	+	1329	WP_181845156.1	MFS transporter	-
L0Y26_RS18580 (L0Y26_18550)	4116186..4116704	+	519	WP_012773344.1	flavodoxin FldB	-
L0Y26_RS18585 (L0Y26_18555)	4116733..4117056	+	324	WP_180777498.1	hypothetical protein	-
L0Y26_RS18590 (L0Y26_18560)	4117102..4118037	-	936	WP_256553822.1	23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF	-
L0Y26_RS18595 (L0Y26_18565)	4118107..4118481	-	375	WP_043881709.1	protein YgfX	Toxin
L0Y26_RS18600 (L0Y26_18570)	4118501..4118767	-	267	WP_012773340.1	FAD assembly factor SdhE	Antitoxin
L0Y26_RS18605 (L0Y26_18575)	4119003..4120004	+	1002	WP_256553823.1	tRNA-modifying protein YgfZ	-
L0Y26_RS18610 (L0Y26_18580)	4120059..4120706	-	648	WP_012773338.1	hemolysin III family protein	-
L0Y26_RS18615 (L0Y26_18585)	4121119..4121727	+	609	WP_181829659.1	HD domain-containing protein	-
L0Y26_RS18620 (L0Y26_18590)	4121771..4122775	+	1005	WP_181847023.1	LacI family DNA-binding transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (2-119)

Antitoxin

• Flavinator of succinate dehydrogenase (8-79)

Sequences

Toxin

Protein

• Length: 125 a.a.
• Molecular weight: 14673.34 Da
• Isoelectric Point: 10.6585

>T231271 WP_043881709.1 NZ_CP090587:c4118481-4118107 [Pectobacterium aroidearum]
MQLLSLIVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQEWQIVKRPWLLKN
GVLLSLQAVNGKDRQQLWLASDSMGDDEWRHLRQLLLQQKNWAR

Nucleotide

• Length: 375 bp

>T231271 NZ_CP126307:c1657513-1657148 [Bosea vestrisii]
GTGATCCTGCTCGATGCCTCGGTCTGGATCGACCATCTGCGGCGCGGCGAGCCCCGCCTTATCGGGATGTTGTCGGAGGG
GGATATCCTGATCCATCCCTTCGTGACCGCCGAGGTGGCGCTCGGTTCGATCGCACGGCGTAGTACCGTGATAGCTGTAC
TTGATGCACTTCCCCAGGCGCCGGTCGCGACACATGGCGAAGTCATGCGCCTGATAGCGCACGAGCATCTGCATGGGCTC
GGCATTGGTTATGTCGATGCCCATCTCCTGGCGTCAGCACGCCTTGCCGACGCTGGCCTCTGGAGCAGAGATCGCCGATT
GCTCGCTGCAGCGGAGCGGCTGGGCGTCGCAGCCGAGGCAACCTGA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10465.94 Da
• Isoelectric Point: 6.2223

>AT231271 WP_012773340.1 NZ_CP090587:c4118767-4118501 [Pectobacterium aroidearum]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLSDSDKRTFVRLLQSDDPDLFNWLMNHGEPKDGELKRMISLIQTRN
KDRGPVAM

Nucleotide

• Length: 267 bp

>AT231271 NZ_CP126307:c1657707-1657510 [Bosea vestrisii]
ATGCGGACGACCGTAACGCTCGATGATGAGCTTATCGAGAAGGCCCAGTTCTATACAGGCATCACCGAACGCTCGGTGCT
GCTGCGGGAAGCGCTGACCGCGTTGATCCAGCGAGAAGCCGCGCGAAGGGCGATCAAGCTGGGTGGCTCCGACCCCGATG
CGACTGCGGCACCGCGCAGGCGTCAGCCTGCGGCGTGA

Structures

Antitoxin

• AlphaFold DB: A0A7W2E501