Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 3199850..3200403 Replicon chromosome
Accession NZ_CP090587
Organism Pectobacterium aroidearum strain AK049

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag L0Y26_RS14675 Protein ID WP_039508990.1
Coordinates 3199850..3200164 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag L0Y26_RS14680 Protein ID WP_039551174.1
Coordinates 3200167..3200403 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y26_RS14630 (L0Y26_14610) 3194898..3195122 + 225 WP_015840869.1 DUF2594 family protein -
L0Y26_RS14635 (L0Y26_14615) 3195215..3195502 - 288 WP_015840870.1 hypothetical protein -
L0Y26_RS14645 (L0Y26_14625) 3196406..3197818 + 1413 WP_181847877.1 D-serine/D-alanine/glycine transporter -
L0Y26_RS14650 (L0Y26_14630) 3197990..3198256 - 267 WP_015840872.1 anti-adapter protein IraP -
L0Y26_RS14655 (L0Y26_14635) 3198652..3198921 - 270 Protein_2871 LysR family transcriptional regulator -
L0Y26_RS14665 (L0Y26_14645) 3199551..3199715 + 165 Protein_2872 Arm DNA-binding domain-containing protein -
L0Y26_RS14670 (L0Y26_14650) 3199715..3199816 + 102 Protein_2873 mobilization protein mobC -
L0Y26_RS14675 (L0Y26_14655) 3199850..3200164 - 315 WP_039508990.1 CcdB family protein Toxin
L0Y26_RS14680 (L0Y26_14660) 3200167..3200403 - 237 WP_039551174.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
L0Y26_RS14685 (L0Y26_14665) 3200731..3201675 - 945 WP_256553541.1 zincin-like metallopeptidase domain-containing protein -
L0Y26_RS14690 (L0Y26_14670) 3202145..3204100 + 1956 WP_256553542.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3177177..3212274 35097


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11521.45 Da        Isoelectric Point: 7.9859

>T231268 WP_039508990.1 NZ_CP090587:c3200164-3199850 [Pectobacterium aroidearum]
MQFTVYGNTGKSVVYPLLLDVTSDIIGQLNRRIVIPLLPIEKYPAGRRPDRLVPVVRLTDGKEYAVMTHELASIPVQALG
AVFCDASQYRSQVKAAIDFLIDGF

Download         Length: 315 bp

>T231268 NZ_CP126279:c86076-85825 [Curtobacterium sp. MCBD17_035]
ATGCGCATCCTCAGCTACTCGGAGACGCGTTCCCACTTCGCCGAGACCCTCAACGCCGTCACGGACGACCGCGAGGAGGT
CGTGGTCACGCGCGCGGGCCACGAATCGGTCGTGCTCGTGTCCCTCGACGACTACGAGTCCCTGAAGGAGACCGCCTACC
TGCTGAGGAACCCCGCGAACGCCCGGCGGCTGCTCGCCTCGATCGAGCGCCTGGAGCGCGGGGAGGGCACGGAGCGGGAC
CTGGACGAGTGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8976.05 Da        Isoelectric Point: 6.4610

>AT231268 WP_039551174.1 NZ_CP090587:c3200403-3200167 [Pectobacterium aroidearum]
MTAKQRNTQSVTMTVERALLVRAREAGINLSATLTTALDAELRYHEAKKWQEENKEALAALNRFHDEQGCFSDEYRTF

Download         Length: 237 bp

>AT231268 NZ_CP126279:c85828-85568 [Curtobacterium sp. MCBD17_035]
GTGAGGTACGTCTGGGACGACGCTGCCTGGGCCGACTACGAGTGGTGGCAACAGCAGGACCGGAAGATCGTCAAGCGGAT
CAACGGGCTGCTCCGTGACATCGCGCGCAACGGCAACGAGGGCATCGGCAAACCGGAGCCGCTCAAGCACGGGTTCCGTG
GGTACTGGTCCCGGCGCATCACGGACGAGCACCGTCTCGCGTACCGCGTCACGGATGACAGCGTCCTCATCGCGCAGTGC
CGGTACCACCACGACGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References