Detailed information of TA system TA231267

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ykfI-yfjZ/CbtA-CbeA
• Location: 3167213..3167937
• Replicon: chromosome
• Accession: NZ_CP090587
• Organism: Pectobacterium aroidearum strain AK049

Toxin (Protein)

• Gene name: ykfI
• Uniprot ID: -
• Locus tag: L0Y26_RS14485
• Protein ID: WP_256553521.1
• Coordinates: 3167213..3167533 (-)
• Length: 107 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: L0Y26_RS14490
• Protein ID: WP_249653329.1
• Coordinates: 3167602..3167937 (-)
• Length: 112 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
L0Y26_RS14455 (L0Y26_14435)	3162514..3163929	+	1416	WP_181848683.1	diguanylate cyclase	-
L0Y26_RS14460 (L0Y26_14440)	3164201..3164419	+	219	WP_015840821.1	KTSC domain-containing protein	-
L0Y26_RS14465 (L0Y26_14445)	3164640..3164996	+	357	WP_182100027.1	hypothetical protein	-
L0Y26_RS14470 (L0Y26_14450)	3165534..3165938	-	405	WP_256553519.1	tRNA(fMet)-specific endonuclease VapC	-
L0Y26_RS14475 (L0Y26_14455)	3165938..3166168	-	231	WP_012765080.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	-
L0Y26_RS14480 (L0Y26_14460)	3166262..3167095	-	834	WP_256553520.1	DUF4942 domain-containing protein	-
L0Y26_RS14485 (L0Y26_14465)	3167213..3167533	-	321	WP_256553521.1	TA system toxin CbtA family protein	Toxin
L0Y26_RS14490 (L0Y26_14470)	3167602..3167937	-	336	WP_249653329.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
L0Y26_RS14495 (L0Y26_14475)	3167977..3168450	-	474	WP_249653330.1	DNA repair protein RadC	-
L0Y26_RS14500 (L0Y26_14480)	3168573..3168923	-	351	WP_256553522.1	hypothetical protein	-
L0Y26_RS14505 (L0Y26_14485)	3168981..3169814	-	834	WP_256553523.1	hypothetical protein	-
L0Y26_RS14510 (L0Y26_14490)	3169961..3170119	-	159	WP_155242703.1	hypothetical protein	-
L0Y26_RS14515 (L0Y26_14495)	3170303..3171190	-	888	WP_256553524.1	50S ribosome-binding GTPase	-
L0Y26_RS14520 (L0Y26_14500)	3171285..3171953	-	669	WP_256553525.1	hypothetical protein	-
L0Y26_RS14525 (L0Y26_14505)	3172327..3172914	+	588	WP_256553526.1	inovirus-type Gp2 protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-105)

Antitoxin

• Antitoxin CbeA (7-106)

Sequences

Toxin

Protein

• Length: 107 a.a.
• Molecular weight: 12077.81 Da
• Isoelectric Point: 4.7768

>T231267 WP_256553521.1 NZ_CP090587:c3167533-3167213 [Pectobacterium aroidearum]
MQTSPAIPPREDNPCPSPIAVWQQLLTYLLEKHYGLTLNDTPFCEENVIQEHIDAGITLVNAVNFLVEKYELVRIDRNGF
NWQEQSPFLTAVDILRARRATGLLKA

Nucleotide

• Length: 321 bp

>T231267 NZ_CP126279:c85828-85568 [Curtobacterium sp. MCBD17_035]
GTGAGGTACGTCTGGGACGACGCTGCCTGGGCCGACTACGAGTGGTGGCAACAGCAGGACCGGAAGATCGTCAAGCGGAT
CAACGGGCTGCTCCGTGACATCGCGCGCAACGGCAACGAGGGCATCGGCAAACCGGAGCCGCTCAAGCACGGGTTCCGTG
GGTACTGGTCCCGGCGCATCACGGACGAGCACCGTCTCGCGTACCGCGTCACGGATGACAGCGTCCTCATCGCGCAGTGC
CGGTACCACCACGACGAGTGA

Antitoxin

Protein

• Length: 112 a.a.
• Molecular weight: 12529.41 Da
• Isoelectric Point: 7.1655

>AT231267 WP_249653329.1 NZ_CP090587:c3167937-3167602 [Pectobacterium aroidearum]
MPSSDTPEWGLKCAITRRFGARLVQEGHRLHYLADRASIVGTFSKTEAQSLERCFPELIKLLEQKLRMGELNPRQQKCVT
LHCNEWICEADTLGSVGYVYIVIYPSSAAAE

Nucleotide

• Length: 336 bp

>AT231267 NZ_CP126279:c86076-85825 [Curtobacterium sp. MCBD17_035]
ATGCGCATCCTCAGCTACTCGGAGACGCGTTCCCACTTCGCCGAGACCCTCAACGCCGTCACGGACGACCGCGAGGAGGT
CGTGGTCACGCGCGCGGGCCACGAATCGGTCGTGCTCGTGTCCCTCGACGACTACGAGTCCCTGAAGGAGACCGCCTACC
TGCTGAGGAACCCCGCGAACGCCCGGCGGCTGCTCGCCTCGATCGAGCGCCTGGAGCGCGGGGAGGGCACGGAGCGGGAC
CTGGACGAGTGA