Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 2107424..2107926 Replicon chromosome
Accession NZ_CP090569
Organism Candidatus Endoriftia persephone isolate Tica-EPR-9o50.N

Toxin (Protein)


Gene name relE Uniprot ID A0A9J6ZU58
Locus tag L0Y14_RS09465 Protein ID WP_039960868.1
Coordinates 2107672..2107926 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag L0Y14_RS09460 Protein ID WP_081417794.1
Coordinates 2107424..2107675 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L0Y14_RS09435 (L0Y14_09425) 2103006..2103431 - 426 WP_081417759.1 DUF2784 domain-containing protein -
L0Y14_RS09440 (L0Y14_09430) 2103951..2104676 + 726 WP_006475861.1 IS110 family transposase -
L0Y14_RS09445 (L0Y14_09435) 2104717..2105319 - 603 WP_006475862.1 carbonate dehydratase -
L0Y14_RS09450 (L0Y14_09440) 2105436..2105834 - 399 WP_039960438.1 phosphate-starvation-inducible PsiE family protein -
L0Y14_RS09455 (L0Y14_09445) 2105979..2106710 - 732 WP_005965199.1 carbonic anhydrase family protein -
L0Y14_RS09460 (L0Y14_09450) 2107424..2107675 + 252 WP_081417794.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
L0Y14_RS09465 (L0Y14_09455) 2107672..2107926 + 255 WP_039960868.1 Txe/YoeB family addiction module toxin Toxin
L0Y14_RS09470 (L0Y14_09460) 2108031..2108417 - 387 WP_138921959.1 hypothetical protein -
L0Y14_RS09475 (L0Y14_09465) 2108634..2108888 - 255 WP_240991757.1 hypothetical protein -
L0Y14_RS09480 (L0Y14_09470) 2109165..2110673 - 1509 WP_240991758.1 hypothetical protein -
L0Y14_RS09485 (L0Y14_09475) 2111780..2112676 - 897 WP_083825220.1 patatin-like phospholipase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2107424..2159079 51655
- inside Integron - - 2098332..2115008 16676


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10186.70 Da        Isoelectric Point: 9.6240

>T231230 WP_039960868.1 NZ_CP090569:2107672-2107926 [Candidatus Endoriftia persephone]
MNLIFADHAWDDYLYWQKVDKKMIKRINSLIKDIQRSPFEGIGKPEPLKHALSGYWSRRINDEHRIIYKVDSESVHIAQL
RYHY

Download         Length: 255 bp

>T231230 NZ_CP126142:16355-16636 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGACCTATGAACTGGCTTTTGACCGCAGAGCACTGAAGGAATGGCAGAAACTCGGCCACACCATCCGTGAACAATTCAA
AAAGAAGCTGGCAGAACGGCTGGAAAATCCACGCGTACCCGCAGCCCGGTTACATGGTCATGCTGATCGCTATAAAATCA
AACTTCGTGCATCTGGCTACAGACTTGTATATCAAGTCATTGATGAGAAAGTCGTTTTACTCGTTATTGCTGTTGGAAGA
AGGGAAAGCAGCGAAGTTTATCAGATTGCAGATATGCGCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9459.76 Da        Isoelectric Point: 5.1665

>AT231230 WP_081417794.1 NZ_CP090569:2107424-2107675 [Candidatus Endoriftia persephone]
MKALSYTAARSNLAKTMESICDDHEPVVITRKNERSVVMLSLEDYESLEETAYLLRSPKNMKRLIESISQIENGNGKPRE
LSE

Download         Length: 252 bp

>AT231230 NZ_CP126142:16114-16365 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGAGCTATCAAATTCTGACAACCACAGCGGCCAGTATTACTGACCTGAAAAAAAATCCTATGGGAACCGTAGCTGAAGG
TGAAGGGGACGCTGTTGCGATCCTGAACCGAAACGAACCGGCGTTCTATTGCGTTCCACCAAAACTTTACGCCTACTATC
GGGAACTCGCTGAAGATGCTGAGTTAAACGCTGTTGCTGATGAGCGCATGAAAAACCCGGAAATTGTGAAGGTTAACCTG
GATGACCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References