Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 226933..227470 Replicon chromosome
Accession NZ_CP090568
Organism Xanthomonas citri pv. malvacearum strain CFBP 2036

Toxin (Protein)


Gene name relE Uniprot ID A0A7X9YU06
Locus tag LPY96_RS01710 Protein ID WP_017158383.1
Coordinates 226933..227214 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7X9UWY6
Locus tag LPY96_RS01715 Protein ID WP_017158384.1
Coordinates 227201..227470 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPY96_RS01680 (LPY96_01675) 222739..224313 - 1575 WP_269339654.1 type IV secretion system DNA-binding domain-containing protein -
LPY96_RS01685 (LPY96_01680) 224317..224490 - 174 Protein_194 hypothetical protein -
LPY96_RS01690 (LPY96_01685) 224490..224885 - 396 WP_269339655.1 conjugal transfer protein TraA -
LPY96_RS01695 (LPY96_01690) 225244..225690 + 447 WP_017160486.1 hypothetical protein -
LPY96_RS01700 (LPY96_01695) 225699..226394 + 696 WP_269339656.1 StbB family protein -
LPY96_RS01705 (LPY96_01700) 226442..226795 + 354 WP_269339657.1 hypothetical protein -
LPY96_RS01710 (LPY96_01705) 226933..227214 - 282 WP_017158383.1 type II toxin-antitoxin system YafQ family toxin Toxin
LPY96_RS01715 (LPY96_01710) 227201..227470 - 270 WP_017158384.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LPY96_RS01720 (LPY96_01715) 227579..228541 - 963 WP_007968792.1 recombinase family protein -
LPY96_RS01725 (LPY96_01720) 228811..228979 - 169 Protein_202 KfrA protein -
LPY96_RS01730 (LPY96_01725) 229093..229374 - 282 WP_269339658.1 CopG family transcriptional regulator -
LPY96_RS01735 (LPY96_01730) 229398..230048 - 651 WP_223304348.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-93)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(7-86)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10679.06 Da        Isoelectric Point: 8.9188

>T231224 WP_017158383.1 NZ_CP090568:c227214-226933 [Xanthomonas citri pv. malvacearum]
MRTIDRSSAFKRDYKREAKGQHRATLDDAIKPVLVALATDQPPDARYRDHDLSGDWAGYRECHIKPDLLLIYRKSDPDTL
RLARLGSHSELFG

Download         Length: 282 bp

>T231224 NZ_CP126140:c4031100-4030792 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGCAATACATGGTTTATCGCAATAAAGGAAACAGCAAGGCTTATCCTTATTTACTTGATGTGCAAAGCGATATTATTGA
TGAACTGCATACTCGCATGGTTATCCCATTGTTTCCTGTGAGCAGATTGGTAAATAACCCAGTTAAGCGCCTCACGCCCA
CTCTGAATGTGGAAGGTAATGACTATCTGGTGATGACTCACGAAATGGCGAGTATCAGGCTTTCGCAGATTGGTGATGAG
GTGATGGACGTTCGTTCCCACAGGCAAACCATCAAAAATGCTCTCGATTTTATCTTTGACGGGTTCTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9719.10 Da        Isoelectric Point: 5.6976

>AT231224 WP_017158384.1 NZ_CP090568:c227470-227201 [Xanthomonas citri pv. malvacearum]
MSTTADTYVRARIDTATKERAASALEAMGLSISDAIRLLMLRIADEHRLPFDVKVPNTTTKKAIAELESGKGKKFANVDD
LMADLHADD

Download         Length: 270 bp

>AT231224 NZ_CP126140:c4031342-4031103 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGCCGGGTATGAGTGTACGACATAAAAAAACAGTCAGTGTCACGCTGGAACCTGCATTGCTTCAGCAAGCCCGTGATGC
AGGTATTAATCTGTCAGCGGTGCTTACCGCCGCGCTGAAAGAGGAAATCAGTGCCACAGGCGTTGAACGCTGGAAAGCAG
AAAATAGAGCGGGTTTGCAGGAGCTCAATCGTATTACTGATGAGCACGGCCTTTTATCGGACGATTACAGGACGTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7X9YU06

Antitoxin

Source ID Structure
AlphaFold DB A0A7X9UWY6

References