Detailed information of TA system TA231223

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mazEF/PemK-MazE
• Location: 219185..219678
• Replicon: chromosome
• Accession: NZ_CP090568
• Organism: Xanthomonas citri pv. malvacearum strain CFBP 2036

Toxin (Protein)

• Gene name: mazF
• Uniprot ID: -
• Locus tag: LPY96_RS01670
• Protein ID: WP_003491151.1
• Coordinates: 219352..219678 (+)
• Length: 109 a.a.

Antitoxin (Protein)

• Gene name: mazE
• Uniprot ID: -
• Locus tag: LPY96_RS01665
• Protein ID: WP_017157755.1
• Coordinates: 219185..219355 (+)
• Length: 57 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LPY96_RS01640 (LPY96_01635)	214852..216072	+	1221	WP_269339651.1	TrbI/VirB10 family protein	-
LPY96_RS01645 (LPY96_01640)	216083..217105	+	1023	WP_269339652.1	P-type DNA transfer ATPase VirB11	-
LPY96_RS01650 (LPY96_01645)	217116..217985	+	870	WP_078566255.1	lytic transglycosylase domain-containing protein	-
LPY96_RS01655 (LPY96_01650)	218111..218530	+	420	WP_078566256.1	hypothetical protein	-
LPY96_RS01660 (LPY96_01655)	218607..218993	+	387	WP_003491149.1	hypothetical protein	-
LPY96_RS01665 (LPY96_01660)	219185..219355	+	171	WP_017157755.1	antitoxin MazE family protein	Antitoxin
LPY96_RS01670 (LPY96_01665)	219352..219678	+	327	WP_003491151.1	type II toxin-antitoxin system PemK/MazF family toxin	Toxin
LPY96_RS01675 (LPY96_01670)	219747..222725	-	2979	WP_269339653.1	MobF family relaxase	-
LPY96_RS01680 (LPY96_01675)	222739..224313	-	1575	WP_269339654.1	type IV secretion system DNA-binding domain-containing protein	-
LPY96_RS01685 (LPY96_01680)	224317..224490	-	174	Protein_194	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	207042..225690	18648

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (2-105)

Antitoxin

• Antitoxin MazE-like (2-54)

Sequences

Toxin

Protein

• Length: 109 a.a.
• Molecular weight: 11690.73 Da
• Isoelectric Point: 9.2550

>T231223 WP_003491151.1 NZ_CP090568:219352-219678 [Xanthomonas citri pv. malvacearum]
MMRGDFVTIAMQGDFGKPRPALVIQADQFDAHTTVTVLPVTSTLVAAPLLRITIHPSTDNGLQKPSQVMVDKAMTVKRDK
VGRAFGRVDADALVEIERCLAVFLGIAK

Nucleotide

• Length: 327 bp

>T231223 NZ_CP126140:c3987106-3986819 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGCCGATGGAGTTTGAATGGGATGCGAACAAGGCTAAAAGCAACCTGAGGAAGCACGGTGTCCGCTTTGAGGATGCGGT
ACTGGTGTTTGACGATCCCCGACACCTGTCACGTCAGGAGCGTTATGAGAATGGAGAATATCGTTGGCAGACCCTCGGCC
TTGTTCATGGCATTGTGGTCATTCTGGTTGCTCATAGCGTTCGGTTCGAAAGTGGTTTTGAAGTTATCCGTATCATCAGC
GCTCGCAAGGCAGACAGAAAAGAGAGGAATCGTTATGAGCATGGTTAA

Antitoxin

Protein

• Length: 57 a.a.
• Molecular weight: 6518.34 Da
• Isoelectric Point: 4.1476

>AT231223 WP_017157755.1 NZ_CP090568:219185-219355 [Xanthomonas citri pv. malvacearum]
MAGLRPVQIWVPDTRRPDFAEECRRQCRLAAQADMADTDMQRFMDEALADMDGWTE

Nucleotide

• Length: 171 bp

>AT231223 NZ_CP126140:c3986832-3986530 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGAGCATGGTTAAACATAAACGCGGCAATGCATCCGCGCTGAGTGCTCAGCATGAGGCTGAACTGAAGGCGCTGGCGAA
AAAATCAGATGATGAGATTGATTACAGCGACATTCCCGCTTCGGAGGATGGGCAGTGGTCTGAAGCAGTGCGTGGTAAGT
TTTTTCGCCCGTTAAAAACTCAGGCCTCGGTGCGTATTGACGCCGATGTGATGGAGTGGCTGAAACGGCCAGGAAAAGGC
TACCAGACGCGGCTCAATGCCATTCTGCGCGAGGCGATGCTGCGCGAGCAAAATAAGAAATAG