Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 119161..119705 Replicon chromosome
Accession NZ_CP090568
Organism Xanthomonas citri pv. malvacearum strain CFBP 2036

Toxin (Protein)


Gene name relE Uniprot ID A0A7X9UUA0
Locus tag LPY96_RS01225 Protein ID WP_033479617.1
Coordinates 119406..119705 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A828YMS8
Locus tag LPY96_RS01220 Protein ID WP_005912560.1
Coordinates 119161..119418 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPY96_RS01205 (LPY96_01200) 114299..115762 - 1464 WP_269339625.1 ribonuclease H-like domain-containing protein -
LPY96_RS01210 (LPY96_01205) 115759..118254 - 2496 WP_165690593.1 DEAD/DEAH box helicase -
LPY96_RS01215 (LPY96_01210) 118432..119094 + 663 WP_005912558.1 hemolysin III family protein -
LPY96_RS01220 (LPY96_01215) 119161..119418 + 258 WP_005912560.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LPY96_RS01225 (LPY96_01220) 119406..119705 + 300 WP_033479617.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LPY96_RS01235 (LPY96_01230) 119885..120784 - 900 WP_269339626.1 SDR family NAD(P)-dependent oxidoreductase -
LPY96_RS01240 (LPY96_01235) 120843..121580 - 738 WP_005912566.1 SDR family oxidoreductase -
LPY96_RS01245 (LPY96_01240) 121706..122617 + 912 WP_005912568.1 LysR family transcriptional regulator -
LPY96_RS01250 (LPY96_01245) 122816..123049 + 234 WP_223304337.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11246.00 Da        Isoelectric Point: 9.7235

>T231222 WP_033479617.1 NZ_CP090568:119406-119705 [Xanthomonas citri pv. malvacearum]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VVVHVMRSERALRGNRLSR

Download         Length: 300 bp

>T231222 NZ_CP126140:3601764-3602021 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGAATGCCTCCGGCGTCAGCGTCCGCCACATCAACAGCAAAACCCACATGACCACCTATTACTCACAAATCCCCAGCCT
GCATCTTAAGGGCGACTGGCTGGAAGAAGCGGGATTTAAGACCGGGCGCGGCGTCACCGTGAAGATTTCACAGGGGTGTA
TTGTGCTGATGGCGGACAGTAACGAGGAGCAGAAGCTGCGCGAGCAGCTTTATCAGGCTAAACAGGTGGTTAAGGGAATT
AAGGACGTGCTGGTTTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9646.15 Da        Isoelectric Point: 8.6223

>AT231222 WP_005912560.1 NZ_CP090568:119161-119418 [Xanthomonas citri pv. malvacearum]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVAEGRTLSHEQAQQRM
ARWLK

Download         Length: 258 bp

>AT231222 NZ_CP126140:c3601939-3601607 [Salmonella enterica subsp. enterica serovar Enteritidis]
TCCGCCATCAGCACAATACACCCCTGTGAAATCTTCACGGTGACGCCGCGCCCGGTCTTAAATCCCGCTTCTTCCAGCCA
GTCGCCCTTAAGATGCAGGCTGGGGATTTGTGAGTAATAGGTGGTCATGTGGGTTTTGCTGTTGATGTGGCGGACGCTGA
CGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTATCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTG
AGCGAGTATGGGCGCGACATCCTGGCACTGAGCCCCCCTCTCCCCGGCCAGCTCCGGGCGGTGATGAGCAACCGGCTGCC
GGGGCCGTATTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7X9UUA0

Antitoxin

Source ID Structure
AlphaFold DB A0A828YMS8

References