Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 116326..116870 Replicon chromosome
Accession NZ_CP090564
Organism Xanthomonas citri pv. malvacearum strain CFBP 2012

Toxin (Protein)


Gene name relE Uniprot ID A0A7X9UUA0
Locus tag LPY95_RS00505 Protein ID WP_033479617.1
Coordinates 116571..116870 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A828YMS8
Locus tag LPY95_RS00500 Protein ID WP_005912560.1
Coordinates 116326..116583 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPY95_RS00485 (LPY95_00485) 111464..112927 - 1464 WP_005921792.1 ribonuclease H-like domain-containing protein -
LPY95_RS00490 (LPY95_00490) 112924..115419 - 2496 WP_165690593.1 DEAD/DEAH box helicase -
LPY95_RS00495 (LPY95_00495) 115597..116259 + 663 WP_005912558.1 hemolysin III family protein -
LPY95_RS00500 (LPY95_00500) 116326..116583 + 258 WP_005912560.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LPY95_RS00505 (LPY95_00505) 116571..116870 + 300 WP_033479617.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LPY95_RS00515 (LPY95_00515) 117050..117950 - 901 Protein_99 SDR family NAD(P)-dependent oxidoreductase -
LPY95_RS00520 (LPY95_00520) 118009..118746 - 738 WP_005912566.1 SDR family oxidoreductase -
LPY95_RS00525 (LPY95_00525) 118872..119783 + 912 WP_005912568.1 LysR family transcriptional regulator -
LPY95_RS00530 (LPY95_00530) 119982..120215 + 234 WP_223304337.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11246.00 Da        Isoelectric Point: 9.7235

>T231214 WP_033479617.1 NZ_CP090564:116571-116870 [Xanthomonas citri pv. malvacearum]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VVVHVMRSERALRGNRLSR

Download         Length: 300 bp

>T231214 NZ_CP126140:310515-310883 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGACCCTACAACTTATCTCAGCGGAAGAGATAATTCAGTTTCACGACAGGCTTCTCCGCGTTACGCCTGGTGTAACAGG
CATGCCTGATCCTGGCCGCGCGGAAGCGCTAATGTACCGGGTACTCAATCAAATCGAATATGAAGGGGTGACCGACGTGT
GGCTGCTGGCGGCAATGCATTTGCTCGCTATATCCCGTGGGCATATCTTCAATGATGGTAACAAACGTACCGCCTTATTT
ATTACGCTGCTGTTTTTAAAGCGTAACGGGATCTCACTCGCTGCGAATCCGGATTTTGTCGATATGACAGTCGATGCGGC
GGCAGGGCGGCTTACGCTGGAGCAAATTGTCGTTCGCTTACGCGCCTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9646.15 Da        Isoelectric Point: 8.6223

>AT231214 WP_005912560.1 NZ_CP090564:116326-116583 [Xanthomonas citri pv. malvacearum]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVAEGRTLSHEQAQQRM
ARWLK

Download         Length: 258 bp

>AT231214 NZ_CP126140:310297-310518 [Salmonella enterica subsp. enterica serovar Enteritidis]
ATGCGTACGGTTAACTATAGCGAAGCGCGGCAAAATCTGGCCGAAGTCCTGGAAAGCGCGGTGACGGCGGGCCCTGTCAC
CATCACGCGTCGTGGGCATAAGTCCGCAGTGATCATCAGCGCCGAGGAGTTTGAGCGTTATCAGACGGCGCGAATGGATG
ATGAGTTTGCTGCCATTATGGCGGTTCATGGCAATGAGCTCAGGGAGCTGGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7X9UUA0

Antitoxin

Source ID Structure
AlphaFold DB A0A828YMS8

References