Detailed information of TA system TA231209

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): EcnAB/-
• Location: 483235..483596
• Replicon: chromosome
• Accession: NZ_CP090561
• Organism: Xanthomonas citri pv. malvacearum strain CFBP 2530

Toxin (Protein)

• Gene name: EcnB
• Uniprot ID: M4UGA1
• Locus tag: LGM68_RS02050
• Protein ID: WP_005914328.1
• Coordinates: 483462..483596 (+)
• Length: 45 a.a.

Antitoxin (Protein)

• Gene name: EcnA
• Uniprot ID: -
• Locus tag: LGM68_RS02045
• Protein ID: WP_269356411.1
• Coordinates: 483235..483387 (+)
• Length: 51 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LGM68_RS02015 (LGM68_02010)	478291..478974	-	684	WP_269356406.1	dTMP kinase	-
LGM68_RS02020 (LGM68_02015)	479456..479998	-	543	WP_003486615.1	GTPase	-
LGM68_RS02025 (LGM68_02020)	479995..480912	-	918	WP_033481739.1	hypothetical protein	-
LGM68_RS02030 (LGM68_02025)	481009..481368	-	360	WP_003486613.1	hypothetical protein	-
LGM68_RS02035 (LGM68_02030)	481432..481884	-	453	WP_003486611.1	roadblock/LC7 domain-containing protein	-
LGM68_RS02040 (LGM68_02035)	482205..483128	+	924	WP_269339738.1	arginase	-
LGM68_RS02045 (LGM68_02040)	483235..483387	+	153	WP_269356411.1	entericidin A/B family lipoprotein	Antitoxin
LGM68_RS02050 (LGM68_02045)	483462..483596	+	135	WP_005914328.1	entericidin A/B family lipoprotein	Toxin
LGM68_RS02055 (LGM68_02050)	483823..484032	+	210	WP_003486601.1	CsbD family protein	-
LGM68_RS02060 (LGM68_02055)	484214..485503	+	1290	WP_269356413.1	tryptophan--tRNA ligase	-
LGM68_RS02065 (LGM68_02060)	485632..486576	+	945	WP_005914330.1	MBL fold metallo-hydrolase	-
LGM68_RS02070 (LGM68_02065)	486768..488459	+	1692	WP_269356415.1	M28 family metallopeptidase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Entericidin A/B (23-42)

Antitoxin

• Entericidin A/B (23-41)

Sequences

Toxin

Protein

• Length: 45 a.a.
• Molecular weight: 4459.32 Da
• Isoelectric Point: 9.3487

>T231209 WP_005914328.1 NZ_CP090561:483462-483596 [Xanthomonas citri pv. malvacearum]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Nucleotide

• Length: 135 bp

>T231209 NZ_CP126138:c4698055-4697744 [Salmonella enterica subsp. enterica serovar Kottbus]
ATGCAATTTATAGAAACGGAACTCTTTACTGAAGATGTTAAAAAACTGCTCGATGATGATGAATACCATAAGCTTCAGGT
TTTTATGGCTCAGCATCCAGATTGTGGTGATGTCATTCAGGAAACGGGCGGCCTGAGAAAAATGCGCTGGGGAGCGCGAG
GCAAAGGAAAGCGTAGTGGCGTGCGAATTATCTATTTTCACCGTAGTCAACGGTATGAGATTCGCTTGCTTCTGATTTAT
CAAAAAGGCATTAAAGATGATCTCACGCCGCAGGAAAAAGCGGTGCTTCGTATGCTGAATGAGAGGTGGTAG

Antitoxin

Protein

• Length: 51 a.a.
• Molecular weight: 5166.12 Da
• Isoelectric Point: 8.7942

>AT231209 WP_269356411.1 NZ_CP090561:483235-483387 [Xanthomonas citri pv. malvacearum]
MKRLLTLMVLGLFSVGVMTGCNTVAGAGKDMQGAGNKVEKTSEKCSDGKC

Nucleotide

• Length: 153 bp

>AT231209 NZ_CP126138:c4697743-4697453 [Salmonella enterica subsp. enterica serovar Kottbus]
ATGGATAAAGTGTTATTTGAGCGATTAACTCAAAGTATGTCTCAAATGAATGAAATCATTGAAGGGACCCGTGAACCTTC
TCGTACCTTTCATATTGATGCAATGAAGATTAAAGAAATACGGCAGGCATCTGGGTTGTCGCAATCTAAGTTTGCAGAGC
TGATTTCGGTCAACGTGGATACGCTGCGCAACTGGGAGCAAGGAAGACGTTCACCGACAGGGCCAGCCAAAGCGTTACTT
CGCGCCATTGCCAACGACCCGAGAAACGTTATACAAGCATTGCGTTATTGA

Structures

Toxin

• AlphaFold DB: A0A3G2W7U6