Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/YafQ-RelB |
| Location | 221694..222231 | Replicon | chromosome |
| Accession | NZ_CP090561 | ||
| Organism | Xanthomonas citri pv. malvacearum strain CFBP 2530 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A0A7X9YU06 |
| Locus tag | LGM68_RS00985 | Protein ID | WP_017158383.1 |
| Coordinates | 221694..221975 (-) | Length | 94 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A7X9UWY6 |
| Locus tag | LGM68_RS00990 | Protein ID | WP_017158384.1 |
| Coordinates | 221962..222231 (-) | Length | 90 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LGM68_RS00955 (LGM68_00950) | 217500..219074 | - | 1575 | WP_269356283.1 | type IV secretion system DNA-binding domain-containing protein | - |
| LGM68_RS00960 (LGM68_00955) | 219078..219251 | - | 174 | Protein_188 | hypothetical protein | - |
| LGM68_RS00965 (LGM68_00960) | 219251..219646 | - | 396 | WP_269356285.1 | conjugal transfer protein TraA | - |
| LGM68_RS00970 (LGM68_00965) | 220005..220451 | + | 447 | WP_017160486.1 | hypothetical protein | - |
| LGM68_RS00975 (LGM68_00970) | 220460..221155 | + | 696 | WP_269356287.1 | StbB family protein | - |
| LGM68_RS00980 (LGM68_00975) | 221203..221556 | + | 354 | WP_269356288.1 | hypothetical protein | - |
| LGM68_RS00985 (LGM68_00980) | 221694..221975 | - | 282 | WP_017158383.1 | type II toxin-antitoxin system YafQ family toxin | Toxin |
| LGM68_RS00990 (LGM68_00985) | 221962..222231 | - | 270 | WP_017158384.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| LGM68_RS00995 (LGM68_00990) | 222697..222933 | - | 237 | Protein_195 | resolvase | - |
| LGM68_RS01000 (LGM68_00995) | 223501..224733 | - | 1233 | Protein_196 | DUF4236 domain-containing protein | - |
| LGM68_RS01005 (LGM68_01000) | 224984..225415 | - | 432 | WP_017170141.1 | recombinase family protein | - |
| LGM68_RS01010 (LGM68_01005) | 225685..225853 | - | 169 | Protein_198 | KfrA protein | - |
| LGM68_RS01015 (LGM68_01010) | 225967..226248 | - | 282 | WP_269339658.1 | CopG family transcriptional regulator | - |
| LGM68_RS01020 (LGM68_01015) | 226272..226922 | - | 651 | WP_223304348.1 | AAA family ATPase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 201281..224987 | 23706 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 94 a.a. Molecular weight: 10679.06 Da Isoelectric Point: 8.9188
>T231208 WP_017158383.1 NZ_CP090561:c221975-221694 [Xanthomonas citri pv. malvacearum]
MRTIDRSSAFKRDYKREAKGQHRATLDDAIKPVLVALATDQPPDARYRDHDLSGDWAGYRECHIKPDLLLIYRKSDPDTL
RLARLGSHSELFG
MRTIDRSSAFKRDYKREAKGQHRATLDDAIKPVLVALATDQPPDARYRDHDLSGDWAGYRECHIKPDLLLIYRKSDPDTL
RLARLGSHSELFG
Download Length: 282 bp
>T231208 NZ_CP126138:c4377696-4377205 [Salmonella enterica subsp. enterica serovar Kottbus]
ATGATCTCCACCCCTGAGCCGCTTCATGCCGGACATATTCTTACTCCGTTTTGCTGCGGTGTGGATTCTATAGATAACTG
GCTGGAACAGCGGGCGATGAAAAATCAGACCACTGGCGCGTCCCGTACCTTTGTGTGTTGTGGCAGCGATTCGAACGTAC
TGGCCTATTACTCGCTGGCGTCCAGCGCGGTCACGACGAATACCTCCCCCGGTCGCTTTCGTCGCAATATGCCTGACCCG
ATTCCGGTTGTGGTATTGGGGCGTCTGGCGGTGGATAAATCGCTTCATGGGCAGGGCGTCGCTCGGGCGCTGGTACGCGA
CGCAGGGCTGCGGGTTATTCAGGTGGCGGAGACTATCGGCATTCGTGGGATGCTGGTTCACGCCCTGTCGGATGAAGCGC
GGGAATTTTATCAGCGGGTGGGGTTTGTACCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGGGGGATTTGGTG
GAGAGTGTTTAA
ATGATCTCCACCCCTGAGCCGCTTCATGCCGGACATATTCTTACTCCGTTTTGCTGCGGTGTGGATTCTATAGATAACTG
GCTGGAACAGCGGGCGATGAAAAATCAGACCACTGGCGCGTCCCGTACCTTTGTGTGTTGTGGCAGCGATTCGAACGTAC
TGGCCTATTACTCGCTGGCGTCCAGCGCGGTCACGACGAATACCTCCCCCGGTCGCTTTCGTCGCAATATGCCTGACCCG
ATTCCGGTTGTGGTATTGGGGCGTCTGGCGGTGGATAAATCGCTTCATGGGCAGGGCGTCGCTCGGGCGCTGGTACGCGA
CGCAGGGCTGCGGGTTATTCAGGTGGCGGAGACTATCGGCATTCGTGGGATGCTGGTTCACGCCCTGTCGGATGAAGCGC
GGGAATTTTATCAGCGGGTGGGGTTTGTACCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGGGGGATTTGGTG
GAGAGTGTTTAA
Antitoxin
Download Length: 90 a.a. Molecular weight: 9719.10 Da Isoelectric Point: 5.6976
>AT231208 WP_017158384.1 NZ_CP090561:c222231-221962 [Xanthomonas citri pv. malvacearum]
MSTTADTYVRARIDTATKERAASALEAMGLSISDAIRLLMLRIADEHRLPFDVKVPNTTTKKAIAELESGKGKKFANVDD
LMADLHADD
MSTTADTYVRARIDTATKERAASALEAMGLSISDAIRLLMLRIADEHRLPFDVKVPNTTTKKAIAELESGKGKKFANVDD
LMADLHADD
Download Length: 270 bp
>AT231208 NZ_CP126138:c4377986-4377693 [Salmonella enterica subsp. enterica serovar Kottbus]
ATGCCAGCCGCAAACAGTATGGCGATGAAACGCGAAACCCTGAACCTGCGTATCAAACCCGCCGAGCGCGATCTTATCGA
TCGAGCGGCGAAAGCCAGAGGGAAAAACCGCACAGACTTTGTGCTGGAAGCTGCCCGCGCTGCCGCAGAGGAAGCGCTTA
TCGAACAACGCATCATTATGGCCGATCCAGAGGCTTATCAGGAGTTTCTCGTTCGTTTGGATCAAACACCTTCACCTAAT
GCCGCACTGCGTAAAACCATGCAGACCCCTGCGCCGTGGGAGCAGGAAAAATGA
ATGCCAGCCGCAAACAGTATGGCGATGAAACGCGAAACCCTGAACCTGCGTATCAAACCCGCCGAGCGCGATCTTATCGA
TCGAGCGGCGAAAGCCAGAGGGAAAAACCGCACAGACTTTGTGCTGGAAGCTGCCCGCGCTGCCGCAGAGGAAGCGCTTA
TCGAACAACGCATCATTATGGCCGATCCAGAGGCTTATCAGGAGTTTCTCGTTCGTTTGGATCAAACACCTTCACCTAAT
GCCGCACTGCGTAAAACCATGCAGACCCCTGCGCCGTGGGAGCAGGAAAAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A7X9YU06 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A7X9UWY6 |