Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 117638..118182 Replicon chromosome
Accession NZ_CP090561
Organism Xanthomonas citri pv. malvacearum strain CFBP 2530

Toxin (Protein)


Gene name relE Uniprot ID A0A7X9UUA0
Locus tag LGM68_RS00515 Protein ID WP_033479617.1
Coordinates 117883..118182 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A828YMS8
Locus tag LGM68_RS00510 Protein ID WP_005912560.1
Coordinates 117638..117895 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LGM68_RS00495 (LGM68_00490) 112776..114239 - 1464 WP_005921792.1 ribonuclease H-like domain-containing protein -
LGM68_RS00500 (LGM68_00495) 114236..116731 - 2496 WP_165690593.1 DEAD/DEAH box helicase -
LGM68_RS00505 (LGM68_00500) 116909..117571 + 663 WP_005912558.1 hemolysin III family protein -
LGM68_RS00510 (LGM68_00505) 117638..117895 + 258 WP_005912560.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LGM68_RS00515 (LGM68_00510) 117883..118182 + 300 WP_033479617.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LGM68_RS00525 (LGM68_00520) 118362..119262 - 901 Protein_101 SDR family NAD(P)-dependent oxidoreductase -
LGM68_RS00530 (LGM68_00525) 119321..120058 - 738 WP_005912566.1 SDR family oxidoreductase -
LGM68_RS00535 (LGM68_00530) 120184..121095 + 912 WP_005912568.1 LysR family transcriptional regulator -
LGM68_RS00540 (LGM68_00535) 121294..121527 + 234 WP_223304337.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11246.00 Da        Isoelectric Point: 9.7235

>T231206 WP_033479617.1 NZ_CP090561:117883-118182 [Xanthomonas citri pv. malvacearum]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VVVHVMRSERALRGNRLSR

Download         Length: 300 bp

>T231206 NZ_CP126138:4175854-4177179 [Salmonella enterica subsp. enterica serovar Kottbus]
ATGAGCCGGAAACAGCAACGTCTGGTAATTTGGATGAACGGCATCAAAGTCGGGTACTGGGAAAAAAGCAAAGGGGTAGA
CAGCTTAGAATACCTTCCTGAATGGGTTGCTGACGAACAGGGAAGGCCGCTGTCATTGTCCCTTCCTTTTACTCCCGGGA
ACCAGGTCTGGCGTGGAAATGTGGTACGTGACTATTTTGATAATTTACTGCCGGACAGCGAAGGCATACGCAGACGTCTG
GCAATGCGTTACAAGGCCGATAGCCTTGAGCCTTTTGATCTGCTGACGGAGCTGGGAAAAGACTGCGTGGGCGCGATACA
GCTGCTTCATGACGGAGATGAACCCACTGATTTATATTCCGTGAAGTATCACCCGCTTACTGAATCAGAAATTGCGGCAA
CTTTGCGTAATACCACGGAGACATTGCTACCGGGCAGGCCAGAAGATAACGACGACTTACGTTTATCTATTGCCGGTGCT
CAGGAGAAAACAGCCCTACTGTGGCATGAAGATCGGTGGTGTATGCCGGAGGGTAATACACCAACGACGCATATATTCAA
GCTACCGCTCGGACTTGTGGGGAACATGAAAGCCGACATGAGCTCGTCGGTTGAAAATGAATGGCTCTGCTCGGTACTTC
TCGGCCAGTACGGGCTCCCCGTGGCAAGAACGCAGATTGCTCACTTTGAAGATCAGAAAGCGCTGGTGGTAGAACGTTTT
GACCGAAAATGGTCAGGAGACGGACAATGGATCATTCGTTTACCCCAGGAGGATATGTGTCAGGCCCTGGGCGTTTCGCC
ATTACGAAAATATCAGGCGGACGGCGGGCCAGGTATATCGGAAATTATGGAGGTTCTGAGTAATTCAGACCGTGCTGAGC
GTGACAAAGCGCAGTTTTTTATGACGCAGATAATTTTCTGGATGATGGCCGCAACAGATGGCCACGCTAAAAATTTCAGT
ATTTCTATTGGGCCACAGGGACGTTATCACCTTACACCAAACTATGATGTGTTGTCGGCATGGCCGGTGATCGGTCATGG
GAACAATCAGATATCCTGGCAGAAGTGCAAACTGGCGATGGCCGTACGTGGCAGTAGCAACTATTACCAGATATATCGAA
TACAACGACGCCACTGGATCAGGCATGGTGAGATAACCGGCCTGAGTAAACAGCAGACAGAGGCGATGATAGAGGAAATC
ATCGCCAGAACCCCGGGTGTCATTGAACGTGTTAGCGGGCTTCTTCCGGACCAGTTCCCCCAGCAGCTTGCGGAAAGTAT
TTTTGATGGAATGAGGCAGCAATGCAGGCGCCTGGCTGAGAAATGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9646.15 Da        Isoelectric Point: 8.6223

>AT231206 WP_005912560.1 NZ_CP090561:117638-117895 [Xanthomonas citri pv. malvacearum]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVAEGRTLSHEQAQQRM
ARWLK

Download         Length: 258 bp

>AT231206 NZ_CP126138:4175556-4175849 [Salmonella enterica subsp. enterica serovar Kottbus]
ATCAATAATGATTACCCGTTAAACACGCTCAACCAGCTGCGTCCCTTGCTCATTGGTTTTCGCAAGGCGAATGGCCTGAC
GCAAAAAGACCTGTCCGAAAGGTTAGGCGTCACTCAACAGACATACTCACGTCTGGAAGCCAACCCTGCCAGTGCGAGCA
TTGAACGGCTATTCAAGGTGTTTTCCATCCTGGGCGTAAAAATCAGCTTCTCCTCGGCAACCACCTCTTCAGAGAGGAAG
CAGACGGAAGAAATGCTTAAATCAAACTCACCTGCACGACAGGAGGATTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7X9UUA0

Antitoxin

Source ID Structure
AlphaFold DB A0A828YMS8

References