231177

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 1965396..1965958 Replicon chromosome
Accession NZ_CP090547
Organism Xylella fastidiosa subsp. sandyi strain OC8

Toxin (Protein)


Gene name parE Uniprot ID A0A060H8A8
Locus tag LZ756_RS09485 Protein ID WP_024748859.1
Coordinates 1965662..1965958 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A060H455
Locus tag LZ756_RS09480 Protein ID WP_020852177.1
Coordinates 1965396..1965674 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZ756_RS09430 (LZ756_09430) 1960408..1960572 + 165 WP_230577906.1 DUF4158 domain-containing protein -
LZ756_RS09435 (LZ756_09435) 1960515..1960655 + 141 WP_230577898.1 DUF4158 domain-containing protein -
LZ756_RS09440 (LZ756_09440) 1960836..1961156 - 321 WP_024748857.1 TrfB-related DNA-binding protein -
LZ756_RS09445 (LZ756_09445) 1961224..1961559 - 336 WP_020852173.1 hypothetical protein -
LZ756_RS09450 (LZ756_09450) 1961618..1961743 - 126 WP_230577899.1 hypothetical protein -
LZ756_RS09455 (LZ756_09455) 1963333..1963764 - 432 WP_024748858.1 hypothetical protein -
LZ756_RS09460 (LZ756_09460) 1963766..1964323 - 558 WP_020852174.1 recombinase family protein -
LZ756_RS09465 (LZ756_09465) 1964341..1964508 - 168 WP_196230068.1 hypothetical protein -
LZ756_RS09470 (LZ756_09470) 1964513..1964887 - 375 WP_020852175.1 DUF5615 family PIN-like protein -
LZ756_RS09475 (LZ756_09475) 1964884..1965114 - 231 WP_004091411.1 DUF433 domain-containing protein -
LZ756_RS09480 (LZ756_09480) 1965396..1965674 + 279 WP_020852177.1 CopG family ribbon-helix-helix protein Antitoxin
LZ756_RS09485 (LZ756_09485) 1965662..1965958 + 297 WP_024748859.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LZ756_RS09490 (LZ756_09490) 1965987..1966250 + 264 WP_080702509.1 hypothetical protein -
LZ756_RS09495 (LZ756_09495) 1966174..1966620 + 447 WP_234759316.1 baseplate J/gp47 family protein -
LZ756_RS09500 (LZ756_09500) 1966622..1966978 + 357 WP_020852180.1 hypothetical protein -
LZ756_RS09505 (LZ756_09505) 1967055..1967282 + 228 WP_020852181.1 hypothetical protein -
LZ756_RS09510 (LZ756_09510) 1967520..1967660 + 141 WP_234759318.1 hypothetical protein -
LZ756_RS09515 (LZ756_09515) 1967717..1967854 + 138 WP_155244237.1 hypothetical protein -
LZ756_RS09520 (LZ756_09520) 1967962..1968222 + 261 WP_024748860.1 hypothetical protein -
LZ756_RS09525 (LZ756_09525) 1969371..1969526 + 156 WP_234759319.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11243.98 Da        Isoelectric Point: 10.4229

>T231177 WP_024748859.1 NZ_CP090547:1965662-1965958 [Xylella fastidiosa subsp. sandyi]
MPRVIFVPEAIRNIQRLRKFLHPKNGDAAKRAGEIVMRGTRMLGAQPRIGRPVDALPDEYREWLIDFGDSGYVAHYRIDG
DTVTILAVRHQKEVGYTR

Download         Length: 297 bp

>T231177 NZ_CP126105:c1241916-1241170 [Bacillus velezensis]
ATGCTTTTGTTTTTTCAGATCATGGTGTGGACGATGGCGGCCGCACTCATTTTATATGTGTACGCATCCTGGCGGTATGA
GGCAAAGGTGAAAGAAAAAATGTTTGCCATCCGTAAAACGTGGTATTTACTATTTGTACTGGGCTCCATGGTCTATTGGA
CATATGATCCTGAATCGCTCTTTGCCGCATGGAGACAATATTTGATTGTTGCCGTCTGCTTTGCCCTTATTGATGCGTTT
ATCTTTTTGAGCGCGTATATCAAAAAGCTCGCCGGCAATGAATTAGAGACGGATACGCGGGAAATTTTAGAAGAAAATAA
CGAAATGCTTCACTCCTATCTTGAAAAACTGAAAACCTATCAATATCTGTTGAAAAATGAACCGATCCATGTATATTATG
GAAGTACAGAAGCTTATGCGGAAGGCATCAGCAGACTGCTGGCCGCTTATGCCGAAAAAATGAATGTCACGGCTTCCTTG
TGCGACTATTCCGCACAATCGGATAAGGACCGCTTGACGGAGCATATGCCTGATGCGGCAGACGTTCAGTCCCGTCTTAA
CCGTAAAGACGTCTACTATGATCAAAAAGGCAGGCTTGTGCTTATTCCGTTTACAGTCCAGAACCGCCATTACGTGATCA
AACTCACGTCGGAAAACCTGTTGACGGAATTCGATTATTTGCTTTTCACATCGCTAACGAGCATTTATGATTTAATGCTG
CCAATAGAAGAGGAAGGTGACGGTTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10737.08 Da        Isoelectric Point: 5.6126

>AT231177 WP_020852177.1 NZ_CP090547:1965396-1965674 [Xylella fastidiosa subsp. sandyi]
MGMATSIKLDDELKGRVQHLADVRRRTAHWIMREAIAQYVEREEKREAFRQDTLKAWEEFQATGLHVTAEEVEKWLSSWG
TENELQAPVCHG

Download         Length: 279 bp

>AT231177 NZ_CP126105:c1241169-1240999 [Bacillus velezensis]
ATGGAGCAGGCATTTCAAAACGGGCAGCCGGAACAAAGAGCGAAACCGTTCAAAATGTTTAAAAAACGTTCAATGACAAG
TATCGCAAGTTACCAGGTCAGCCCTCATACCGCCAGAATTTTCAAAGAAAACGAGCGGCTGATTGACAAGTATAAACAAA
AAAAAGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A060H8A8

Antitoxin

Source ID Structure
AlphaFold DB A0A060H455

References