Detailed information of TA system TA231168

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-dinJ/YafQ-RelB
• Location: 461703..462234
• Replicon: chromosome
• Accession: NZ_CP090547
• Organism: Xylella fastidiosa subsp. sandyi strain OC8

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A060GYI0
• Locus tag: LZ756_RS01910
• Protein ID: WP_020853121.1
• Coordinates: 461953..462234 (+)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: dinJ
• Uniprot ID: A0A060H1U9
• Locus tag: LZ756_RS01905
• Protein ID: WP_020853122.1
• Coordinates: 461703..461966 (+)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LZ756_RS01880 (LZ756_01880)	456929..458107	-	1179	WP_020850953.1	phage tail sheath family protein	-
LZ756_RS01885 (LZ756_01885)	458172..459764	-	1593	WP_024748652.1	tail fiber domain-containing protein	-
LZ756_RS01890 (LZ756_01890)	459772..460329	-	558	WP_020852723.1	phage tail protein I	-
LZ756_RS01895 (LZ756_01895)	460322..461215	-	894	WP_020850956.1	baseplate J/gp47 family protein	-
LZ756_RS01900 (LZ756_01900)	461215..461538	-	324	WP_228304176.1	GPW/gp25 family protein	-
LZ756_RS01905 (LZ756_01905)	461703..461966	+	264	WP_020853122.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
LZ756_RS01910 (LZ756_01910)	461953..462234	+	282	WP_020853121.1	type II toxin-antitoxin system YafQ family toxin	Toxin
LZ756_RS01915 (LZ756_01915)	462271..462858	-	588	WP_024748577.1	phage baseplate assembly protein V	-
LZ756_RS01920 (LZ756_01920)	462855..463397	-	543	WP_020852726.1	hypothetical protein	-
LZ756_RS01925 (LZ756_01925)	463373..463894	-	522	WP_020852727.1	hypothetical protein	-
LZ756_RS01930 (LZ756_01930)	463891..464214	-	324	WP_234759353.1	hypothetical protein	-
LZ756_RS01935 (LZ756_01935)	464214..464474	-	261	WP_020850964.1	hypothetical protein	-
LZ756_RS01940 (LZ756_01940)	464492..466366	-	1875	WP_020850965.1	phage major capsid protein	-
LZ756_RS01945 (LZ756_01945)	466363..466995	-	633	WP_020850966.1	phage portal protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	434411..471107	36696

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-91)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (4-70)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10892.32 Da
• Isoelectric Point: 7.2205

>T231168 WP_020853121.1 NZ_CP090547:461953-462234 [Xylella fastidiosa subsp. sandyi]
MRRISQTGQFKRDYKREAKGQHRATLDEELIHVVEALACDHPLEPRHHDHALTGDWKDHRDCHIKPDLVLIYRKPDNETL
QLVRIGSHSELGL

Nucleotide

• Length: 282 bp

>T231168 NZ_CP126100:521224-521574 [Bacillus halotolerans]
TTGATTGTGAAACGCGGCGATGTTTATTTTGCTGATTTATCTCCTGTTGTTGGCTCAGAGCAAGGCGGGGTGCGCCCGGT
TTTAGTGATCCAAAATGACATCGGAAATCGCTTCAGCCCAACTGCTATTGTTGCAGCCATAACAGCCCAAATACAGAAAG
CGAAATTACCAACCCACGTCGAAATTGATGCAAAACGCTACGGTTTTGAAAGAGATTCCGTTATTTTGCTGGAGCAAATT
CGGACGATTGACAAGCAAAGGTTAACGGATAAGATTACTCATCTGGATGATGAAATGATGGATAAGGTTGATGAAGCCTT
ACAGATCAGTTTGGCACTCATTGATTTTTAG

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9422.90 Da
• Isoelectric Point: 6.7245

>AT231168 WP_020853122.1 NZ_CP090547:461703-461966 [Xylella fastidiosa subsp. sandyi]
MSANAVVRARVDAHIKEEASTVLATMGLSVSDAFRMMLTRIAREKALPFEPLVPNATTIAAMREARAGHLKSFNSIEGLM
ADLHAED

Nucleotide

• Length: 264 bp

>AT231168 NZ_CP126100:520938-521219 [Bacillus halotolerans]
TTGTCTGAATCCAGCGCAAGAACCGAAATGAAAATCAGCTTGCCCGAAAACCTAGTAGCTGAATTGGATGGTGTAGCGAT
GCGGGAGAAACGAAGCAGAAACGAACTGATATCACAAGCAGTGAGAGCCTATGTCAGCGAACGAACAACTCGTCACAACC
GTGATTTGATGAGACGCGGCTATATGGAAATGGCGAAAATCAACCTGAACATTTCTTCCGAGGCTCACTTTGCGGAGTGC
GAGGCTGAAACGACAGTTGAGCGCTTAGTCAGCGGAGGATAA

Structures

Toxin

• AlphaFold DB: A0A060GYI0

Antitoxin

• AlphaFold DB: A0A060H1U9