Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | tacAT/DUF1778(antitoxin) |
| Location | 4424063..4424844 | Replicon | chromosome |
| Accession | NZ_CP090539 | ||
| Organism | Salmonella enterica strain 2016062-SE | ||
Toxin (Protein)
| Gene name | TacT2 | Uniprot ID | E8X9W8 |
| Locus tag | L0F59_RS21720 | Protein ID | WP_000626099.1 |
| Coordinates | 4424063..4424554 (-) | Length | 164 a.a. |
Antitoxin (Protein)
| Gene name | TacA2 | Uniprot ID | B5R979 |
| Locus tag | L0F59_RS21725 | Protein ID | WP_001110452.1 |
| Coordinates | 4424551..4424844 (-) | Length | 98 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| L0F59_RS21685 (4420058) | 4420058..4420633 | + | 576 | WP_001188509.1 | transcriptional regulator | - |
| L0F59_RS21695 (4420904) | 4420904..4420981 | - | 78 | Protein_4250 | helix-turn-helix domain-containing protein | - |
| L0F59_RS21700 (4421072) | 4421072..4421404 | - | 333 | WP_001165471.1 | MerR family transcriptional regulator | - |
| L0F59_RS21705 (4421476) | 4421476..4421853 | + | 378 | WP_000916345.1 | EthD family reductase | - |
| L0F59_RS21710 (4422886) | 4422886..4422960 | + | 75 | Protein_4253 | porin family protein | - |
| L0F59_RS21715 (4423063) | 4423063..4423815 | + | 753 | WP_000842434.1 | non-specific acid phosphatase | - |
| L0F59_RS21720 (4424063) | 4424063..4424554 | - | 492 | WP_000626099.1 | GNAT family N-acetyltransferase | Toxin |
| L0F59_RS21725 (4424551) | 4424551..4424844 | - | 294 | WP_001110452.1 | DUF1778 domain-containing protein | Antitoxin |
| L0F59_RS21730 (4425161) | 4425161..4425382 | + | 222 | WP_001576552.1 | hypothetical protein | - |
| L0F59_RS21735 (4425647) | 4425647..4426522 | + | 876 | WP_000921674.1 | AraC family transcriptional regulator | - |
| L0F59_RS21740 (4426519) | 4426519..4426806 | + | 288 | WP_001269916.1 | transcriptional regulator RtsB | - |
| L0F59_RS21745 (4426829) | 4426829..4427044 | + | 216 | WP_001595136.1 | hypothetical protein | - |
| L0F59_RS21750 (4427052) | 4427052..4427321 | + | 270 | WP_010989096.1 | hypothetical protein | - |
| L0F59_RS21755 (4427615) | 4427615..4428520 | - | 906 | WP_001268200.1 | YjiK family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 164 a.a. Molecular weight: 17646.39 Da Isoelectric Point: 6.8437
>T231114 WP_000626099.1 NZ_CP090539:c4424554-4424063 [Salmonella enterica]
MISTPEPLHAGHILTPFCCGVDSIDNWLEQRAMKNQTTGASRTFVCCGSDSNVLAYYSLASSAVTTNTSPGRFRRNMPDP
IPVVVLGRLAVDKSLHGQGVARALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYQRVGFVPSPMDPMMLMVTLGDLV
ESV
MISTPEPLHAGHILTPFCCGVDSIDNWLEQRAMKNQTTGASRTFVCCGSDSNVLAYYSLASSAVTTNTSPGRFRRNMPDP
IPVVVLGRLAVDKSLHGQGVARALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYQRVGFVPSPMDPMMLMVTLGDLV
ESV
Download Length: 492 bp
>T231114 NZ_CP125998:25119-25682 [Myroides odoratimimus]
ATGATTCATAGTGTACGATACAAAGCTGTTCTTGATACCAATGTAATATTTCCTATCGTGATTAGAGATTTATTATTTTG
GTTTGCTCATTATGATTTATATACCCCAAAATGGAGTAAAATCATTTTTGATGAATGGAAATCTGTAATGATTCGAAAGG
GAGTTGAATCTTCCCAAGCAGAGAAGCGGATAAACGTTGCAAATTTGGCATTTCCCGATGCTTTAGTACTAAATTATGAA
GGTTTAATTGATAATTTAAATTTACCTGATAAAGATGATAGACATGTATTAGCTGCTGCTATTAAAGTCAATGCCAATAT
TATTGTAACTAATAACTTAAAGGATTTTCCAGATGATTATTTAGACTCTTTTGGATTGAAGGCAGTTTGTGCGGATGATT
TTCTTACAGATATCATTGATTTAAATCCAAAAATAGCCCTCCAAGCTTTTAAAGATTTGGTATTAAATCGCAAAAACCCG
GCAATGGATGAATTTCAAGTATTAGAAAGTTTTAGAAAAAATGGATTAAATCAAACAGCAGATTATTTACATGCTTTATT
GTAA
ATGATTCATAGTGTACGATACAAAGCTGTTCTTGATACCAATGTAATATTTCCTATCGTGATTAGAGATTTATTATTTTG
GTTTGCTCATTATGATTTATATACCCCAAAATGGAGTAAAATCATTTTTGATGAATGGAAATCTGTAATGATTCGAAAGG
GAGTTGAATCTTCCCAAGCAGAGAAGCGGATAAACGTTGCAAATTTGGCATTTCCCGATGCTTTAGTACTAAATTATGAA
GGTTTAATTGATAATTTAAATTTACCTGATAAAGATGATAGACATGTATTAGCTGCTGCTATTAAAGTCAATGCCAATAT
TATTGTAACTAATAACTTAAAGGATTTTCCAGATGATTATTTAGACTCTTTTGGATTGAAGGCAGTTTGTGCGGATGATT
TTCTTACAGATATCATTGATTTAAATCCAAAAATAGCCCTCCAAGCTTTTAAAGATTTGGTATTAAATCGCAAAAACCCG
GCAATGGATGAATTTCAAGTATTAGAAAGTTTTAGAAAAAATGGATTAAATCAAACAGCAGATTATTTACATGCTTTATT
GTAA
Antitoxin
Download Length: 98 a.a. Molecular weight: 10977.61 Da Isoelectric Point: 8.6141
>AT231114 WP_001110452.1 NZ_CP090539:c4424844-4424551 [Salmonella enterica]
MPAANSMAMKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPEAYQEFLVRLDQTPSPN
AALRKTMQTPAPWEQEK
MPAANSMAMKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPEAYQEFLVRLDQTPSPN
AALRKTMQTPAPWEQEK
Download Length: 294 bp
>AT231114 NZ_CP125998:24674-25129 [Myroides odoratimimus]
ATGGAAACATTAGACTATATAAAAAGACCCACTAAGAAAGAACAACGAGTGGCTATTGAATCTTATTCAGCACTTTCTTC
AATTTTATCACAATTGAAGAATGATGATACAGAAATAGAAATCGAAGAAACAAATGACAGAATTAAAATACCTTTTAAAG
CTTTAAAGCTTTTAAGTGAAATTTTGAAGTCAATGAGTGAAGGAAATCCAATATCTATTGTACCTATTGCAACGGAAGTC
ACTACTCAAAAAGCAGCTGAAATATTGGGTTGTTCAAGACCTCATTTAGTTAAACTTTTAGAGCAAGGCGAAATTGATTT
TACAATGGTTGGAAGACATCGTCGTATTTTATTTGAAGATGTAATCAAATATAAAAACGAAATGAAGCAAAAACAGAAAA
AGCATATCATTGATATTATGAACTTTGATGATGAAATAGGTTTATATGATTCATAG
ATGGAAACATTAGACTATATAAAAAGACCCACTAAGAAAGAACAACGAGTGGCTATTGAATCTTATTCAGCACTTTCTTC
AATTTTATCACAATTGAAGAATGATGATACAGAAATAGAAATCGAAGAAACAAATGACAGAATTAAAATACCTTTTAAAG
CTTTAAAGCTTTTAAGTGAAATTTTGAAGTCAATGAGTGAAGGAAATCCAATATCTATTGTACCTATTGCAACGGAAGTC
ACTACTCAAAAAGCAGCTGAAATATTGGGTTGTTCAAGACCTCATTTAGTTAAACTTTTAGAGCAAGGCGAAATTGATTT
TACAATGGTTGGAAGACATCGTCGTATTTTATTTGAAGATGTAATCAAATATAAAAACGAAATGAAGCAAAAACAGAAAA
AGCATATCATTGATATTATGAACTTTGATGATGAAATAGGTTTATATGATTCATAG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|