Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | shpAB/BrnT-BrnA |
| Location | 4200697..4201273 | Replicon | chromosome |
| Accession | NZ_CP090539 | ||
| Organism | Salmonella enterica strain 2016062-SE | ||
Toxin (Protein)
| Gene name | shpA | Uniprot ID | M7RG88 |
| Locus tag | L0F59_RS20655 | Protein ID | WP_001131963.1 |
| Coordinates | 4200986..4201273 (-) | Length | 96 a.a. |
Antitoxin (Protein)
| Gene name | shpB | Uniprot ID | B5R9R5 |
| Locus tag | L0F59_RS20650 | Protein ID | WP_000063142.1 |
| Coordinates | 4200697..4200999 (-) | Length | 101 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| L0F59_RS20635 (4197207) | 4197207..4199357 | + | 2151 | WP_000379927.1 | pyruvate/proton symporter BtsT | - |
| L0F59_RS20640 (4199452) | 4199452..4199655 | + | 204 | WP_000460616.1 | YbdD/YjiX family protein | - |
| L0F59_RS20645 (4199666) | 4199666..4200622 | + | 957 | WP_000187839.1 | GTPase | - |
| L0F59_RS20650 (4200697) | 4200697..4200999 | - | 303 | WP_000063142.1 | BrnA antitoxin family protein | Antitoxin |
| L0F59_RS20655 (4200986) | 4200986..4201273 | - | 288 | WP_001131963.1 | BrnT family toxin | Toxin |
| L0F59_RS20660 (4201542) | 4201542..4202456 | - | 915 | WP_000290512.1 | restriction endonuclease | - |
| L0F59_RS20665 (4202654) | 4202654..4206163 | + | 3510 | WP_001043484.1 | type I restriction-modification system endonuclease | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 11294.80 Da Isoelectric Point: 9.5894
>T231112 WP_001131963.1 NZ_CP090539:c4201273-4200986 [Salmonella enterica]
MPMEFEWDANKAKSNLRKHGVRFEDAVLVFDDPRHLSRQERYENGEYRWQTLGLVHGIVVILVAHSVRFESGFEVIRIIS
ARKADRKERNRYEHG
MPMEFEWDANKAKSNLRKHGVRFEDAVLVFDDPRHLSRQERYENGEYRWQTLGLVHGIVVILVAHSVRFESGFEVIRIIS
ARKADRKERNRYEHG
Download Length: 288 bp
>T231112 NZ_CP125996:c4007546-4007286 [Gordonia sp. L191]
ATGTCTATCAGTGCGAGTGAGGCGCGGAAGTTGCTGTTTCCGCTGATCGAGCAGGTCAACGACGATCGGAGTGCGATCGA
AATCGTGTCTCGGAAGGGCAATGCGGTGCTGATGTCGGCCGACGAGTACGCGGCGTGGCAGGAGACGGCTTACCTGTTCA
GGTCGCCGGCCAACGCCCGCCGACTGTTGGAGTCCTACACACGTGTCTCCGTGGGGCAGACCGAGGTGCATGACCTCGAC
CGGACCGACGGGGACGGCTGA
ATGTCTATCAGTGCGAGTGAGGCGCGGAAGTTGCTGTTTCCGCTGATCGAGCAGGTCAACGACGATCGGAGTGCGATCGA
AATCGTGTCTCGGAAGGGCAATGCGGTGCTGATGTCGGCCGACGAGTACGCGGCGTGGCAGGAGACGGCTTACCTGTTCA
GGTCGCCGGCCAACGCCCGCCGACTGTTGGAGTCCTACACACGTGTCTCCGTGGGGCAGACCGAGGTGCATGACCTCGAC
CGGACCGACGGGGACGGCTGA
Antitoxin
Download Length: 101 a.a. Molecular weight: 11373.96 Da Isoelectric Point: 10.1293
>AT231112 WP_000063142.1 NZ_CP090539:c4200999-4200697 [Salmonella enterica]
MSMVKHKRGNASALSAQHEAELKALAKKSDDEIDYSDIPASEDGQWSEAVRGKFFRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLREQNKK
MSMVKHKRGNASALSAQHEAELKALAKKSDDEIDYSDIPASEDGQWSEAVRGKFFRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLREQNKK
Download Length: 303 bp
>AT231112 NZ_CP125996:c4007285-4007031 [Gordonia sp. L191]
GTGCGTCTGGTCTGGGACCAATCGGCATGGGAAGACTATGTGCACTGGCAAACCGCTGACCGGCGACTACTGAAGCGGAT
CAACACCCTGCTCGACGCGTGCCTGCGCGATGCATTCACCGGCATCGGAAAACCCGAACCGCTCAAGTATGGAGTCCCGG
GCGCCTGGTCGCGGCGCATCTCCGACGAACACCGGCTCGTCTACCTCGTCGATGGCGATGACTTGATCATTCTGCAGGCT
CGGTACCACTACTGA
GTGCGTCTGGTCTGGGACCAATCGGCATGGGAAGACTATGTGCACTGGCAAACCGCTGACCGGCGACTACTGAAGCGGAT
CAACACCCTGCTCGACGCGTGCCTGCGCGATGCATTCACCGGCATCGGAAAACCCGAACCGCTCAAGTATGGAGTCCCGG
GCGCCTGGTCGCGGCGCATCTCCGACGAACACCGGCTCGTCTACCTCGTCGATGGCGATGACTTGATCATTCTGCAGGCT
CGGTACCACTACTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|