Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | tacAT/DUF1778(antitoxin) |
| Location | 4438323..4439104 | Replicon | chromosome |
| Accession | NZ_CP090535 | ||
| Organism | Salmonella enterica strain 2016089-SE | ||
Toxin (Protein)
| Gene name | TacT2 | Uniprot ID | E8X9W8 |
| Locus tag | L0F58_RS21750 | Protein ID | WP_000626099.1 |
| Coordinates | 4438323..4438814 (-) | Length | 164 a.a. |
Antitoxin (Protein)
| Gene name | TacA2 | Uniprot ID | B5R979 |
| Locus tag | L0F58_RS21755 | Protein ID | WP_001110452.1 |
| Coordinates | 4438811..4439104 (-) | Length | 98 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| L0F58_RS21710 (4433509) | 4433509..4433751 | - | 243 | WP_197603740.1 | hypothetical protein | - |
| L0F58_RS21715 (4433748) | 4433748..4434104 | - | 357 | WP_033567083.1 | hypothetical protein | - |
| L0F58_RS21720 (4434101) | 4434101..4434973 | - | 873 | WP_033567082.1 | ParA family protein | - |
| L0F58_RS21725 (4435164) | 4435164..4435241 | - | 78 | Protein_4254 | helix-turn-helix domain-containing protein | - |
| L0F58_RS21730 (4435332) | 4435332..4435664 | - | 333 | WP_001165471.1 | MerR family transcriptional regulator | - |
| L0F58_RS21735 (4435736) | 4435736..4436113 | + | 378 | WP_000916345.1 | EthD family reductase | - |
| L0F58_RS21740 (4437146) | 4437146..4437220 | + | 75 | Protein_4257 | porin family protein | - |
| L0F58_RS21745 (4437323) | 4437323..4438075 | + | 753 | WP_000842434.1 | non-specific acid phosphatase | - |
| L0F58_RS21750 (4438323) | 4438323..4438814 | - | 492 | WP_000626099.1 | GNAT family N-acetyltransferase | Toxin |
| L0F58_RS21755 (4438811) | 4438811..4439104 | - | 294 | WP_001110452.1 | DUF1778 domain-containing protein | Antitoxin |
| L0F58_RS21760 (4439421) | 4439421..4439642 | + | 222 | WP_001576552.1 | hypothetical protein | - |
| L0F58_RS21765 (4439907) | 4439907..4440782 | + | 876 | WP_000921674.1 | AraC family transcriptional regulator | - |
| L0F58_RS21770 (4440779) | 4440779..4441066 | + | 288 | WP_001269916.1 | transcriptional regulator RtsB | - |
| L0F58_RS21775 (4441089) | 4441089..4441304 | + | 216 | WP_001595136.1 | hypothetical protein | - |
| L0F58_RS21780 (4441312) | 4441312..4441581 | + | 270 | WP_010989096.1 | hypothetical protein | - |
| L0F58_RS21785 (4441875) | 4441875..4442780 | - | 906 | WP_001268200.1 | YjiK family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 164 a.a. Molecular weight: 17646.39 Da Isoelectric Point: 6.8437
>T231088 WP_000626099.1 NZ_CP090535:c4438814-4438323 [Salmonella enterica]
MISTPEPLHAGHILTPFCCGVDSIDNWLEQRAMKNQTTGASRTFVCCGSDSNVLAYYSLASSAVTTNTSPGRFRRNMPDP
IPVVVLGRLAVDKSLHGQGVARALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYQRVGFVPSPMDPMMLMVTLGDLV
ESV
MISTPEPLHAGHILTPFCCGVDSIDNWLEQRAMKNQTTGASRTFVCCGSDSNVLAYYSLASSAVTTNTSPGRFRRNMPDP
IPVVVLGRLAVDKSLHGQGVARALVRDAGLRVIQVAETIGIRGMLVHALSDEAREFYQRVGFVPSPMDPMMLMVTLGDLV
ESV
Download Length: 492 bp
>T231088 NZ_CP125957:c2207375-2207088 [Pseudomonas sp. G2-4]
ATCTCATCAAAACAAACGCAGACGTTCACTGCTTGGCATTCATCGATCCGTGATCTGCGAGCAAAAATCGCTATCGCCCG
CCGCATTGATCGCGCTGCAGCAGGTAACCTGAGCGATGTAAAACCTGTCGGTGATGGTATTTCAGAATTGCGTGTGGATG
TAGGCGCTGGCTACCGGGTCTATTTCACCCTGCGCGGTGGAGTGGTCATCGTGCTATTGGCTGGTGGTGACAAGTCTTCA
CAGAGTGCTGATATCCGGCGAGCGAAGAAATTGGCAAAGGAGATTTGA
ATCTCATCAAAACAAACGCAGACGTTCACTGCTTGGCATTCATCGATCCGTGATCTGCGAGCAAAAATCGCTATCGCCCG
CCGCATTGATCGCGCTGCAGCAGGTAACCTGAGCGATGTAAAACCTGTCGGTGATGGTATTTCAGAATTGCGTGTGGATG
TAGGCGCTGGCTACCGGGTCTATTTCACCCTGCGCGGTGGAGTGGTCATCGTGCTATTGGCTGGTGGTGACAAGTCTTCA
CAGAGTGCTGATATCCGGCGAGCGAAGAAATTGGCAAAGGAGATTTGA
Antitoxin
Download Length: 98 a.a. Molecular weight: 10977.61 Da Isoelectric Point: 8.6141
>AT231088 WP_001110452.1 NZ_CP090535:c4439104-4438811 [Salmonella enterica]
MPAANSMAMKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPEAYQEFLVRLDQTPSPN
AALRKTMQTPAPWEQEK
MPAANSMAMKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIEQRIIMADPEAYQEFLVRLDQTPSPN
AALRKTMQTPAPWEQEK
Download Length: 294 bp
>AT231088 NZ_CP125957:c2207085-2206777 [Pseudomonas sp. G2-4]
ATGAGCCAACACCTGACGACATTTGACATGGCGGCACTACTCGATAGCGATGAAGCGATCAGTGAATACCTTTCTCAGGT
GTTGGCTGATGGTGATAGCGAGGAGTTTCTCCGAGCGATCGGCTATGTAGCCAAGGCCCGAGGCATGGCGCAGATCGCTA
AAGACTCTGGCATGGGACGAGAAAGCTTGTACAAGGCGTTCGCACCCGGATCAAAACCGAGATTCGATACCGTACTCAAG
GTCATTCATGCGCTAGGTATTGATCTTCATGCGCAGCCTGGGCATGCAGCTAATCATTCACCGGTCTGA
ATGAGCCAACACCTGACGACATTTGACATGGCGGCACTACTCGATAGCGATGAAGCGATCAGTGAATACCTTTCTCAGGT
GTTGGCTGATGGTGATAGCGAGGAGTTTCTCCGAGCGATCGGCTATGTAGCCAAGGCCCGAGGCATGGCGCAGATCGCTA
AAGACTCTGGCATGGGACGAGAAAGCTTGTACAAGGCGTTCGCACCCGGATCAAAACCGAGATTCGATACCGTACTCAAG
GTCATTCATGCGCTAGGTATTGATCTTCATGCGCAGCCTGGGCATGCAGCTAATCATTCACCGGTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|